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KNSTRN and MPHOSPH6
Number of citations of the paper that reports this interaction (PubMedID
15231747
)
47
Data Source:
HPRD
(two hybrid)
KNSTRN
MPHOSPH6
Description
kinetochore localized astrin (SPAG5) binding protein
M-phase phosphoprotein 6
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Kinetochore
Spindle Pole
Ruffle
Nucleus
Chromosome
Cytoplasm
Microtubule Organizing Center
Cytoskeleton
Microtubule
Plasma Membrane
Centriolar Satellite
Microtubule Plus-end
Mitotic Spindle
Nuclear Exosome (RNase Complex)
Exosome (RNase Complex)
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Molecular Function
Protein Binding
Protein Homodimerization Activity
Microtubule Plus-end Binding
RNA Binding
Protein Binding
Biological Process
Mitotic Sister Chromatid Segregation
Microtubule Cytoskeleton Organization
Spindle Organization
Chromosome Segregation
Cell Migration
Cell Division
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Cellular Response To Epidermal Growth Factor Stimulus
Maturation Of 5.8S RRNA
RRNA Processing
Pathways
Major pathway of rRNA processing in the nucleolus and cytosol
Nuclear RNA decay
Drugs
Diseases
GWAS
Heschl's gyrus morphology (
25130324
)
Malaria (
31844061
)
Leukocyte telomere length (
31171785
32109421
)
Lung adenocarcinoma (
28604730
)
Nevus count or cutaneous melanoma (
32341527
)
Obesity-related traits (
23251661
)
Parkinson's disease motor subtype (tremor dominant vs postural instability/gait difficulty) (
33987465
)
Seasonality and depression (
30217971
)
Interacting Genes
17 interacting genes:
ABI2
BEX2
CHMP1B
CLU
HSPB1
IFT20
MAPK6
MAPRE1
MAPRE3
MECOM
MPHOSPH6
NUPR1
OIP5
PALS2
PPL
WASHC3
ZDHHC17
28 interacting genes:
AATF
APLP1
ARHGAP18
CRYAA
DNM2
DYNLRB1
EIF3G
ERG28
EXOSC10
EXOSC3
EXOSC5
FTL
GDF9
HSPB1
KNSTRN
LRIF1
MTREX
NUPR1
PARN
RBM48
RPS20
SMARCA4
SNX9
THOP1
TLE1
TP53
UNC119
ZHX1
Entrez ID
90417
10200
HPRD ID
12669
16111
Ensembl ID
ENSG00000128944
ENSG00000135698
Uniprot IDs
Q9Y448
H3BNT4
Q99547
PDB IDs
6D6Q
6D6R
6H25
Enriched GO Terms of Interacting Partners
?
Mitotic Spindle Astral Microtubule End
Regulation Of Organelle Organization
Regulation Of Supramolecular Fiber Organization
Intracellular Protein Localization
Cellular Component Assembly
Regulation Of Cytoskeleton Organization
Protein Localization To Microtubule
Microtubule Plus-end Binding
Regulation Of Cellular Component Organization
Protein Serine/threonine Kinase Binding
Microtubule Plus-end
Cytoskeleton
Spindle Midzone
Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Protein Transport
Regulation Of Actin Nucleation
Regulation Of Microtubule Cytoskeleton Organization
Positive Regulation Of Supramolecular Fiber Organization
Perinuclear Endoplasmic Reticulum Lumen
Establishment Of Protein Localization
Regulation Of Intrinsic Apoptotic Signaling Pathway
Regulation Of Neuronal Signal Transduction
Negative Regulation Of Protein Kinase C Signaling
Identical Protein Binding
Positive Regulation Of Dendritic Spine Development
Regulation Of Dendritic Spine Morphogenesis
Cell Division
Protein Localization To Astral Microtubule
Perforant Pathway To Dendrate Granule Cell Synapse
Regulation Of Autophagosome Assembly
Protein Localization To Cytoskeleton
Regulation Of Dendritic Spine Development
Positive Regulation Of Cellular Component Biogenesis
Cornified Envelope
Cytoplasmic Microtubule
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Neurofibrillary Tangle Assembly
Protein-containing Complex Organization
Septin Cytoskeleton
Actin Polymerization Or Depolymerization
Zonula Adherens Assembly
Protein Localization To Mitotic Spindle
Regulation Of Microtubule Polymerization
Protein Localization To Spindle Microtubule
Postsynaptic Golgi Apparatus
Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission
Regulation Of Vacuole Organization
Regulation Of Organelle Assembly
Opsin Transport
Intraciliary Transport Particle
Poly(A)-dependent SnoRNA 3'-end Processing
Sno(s)RNA Metabolic Process
Exosome (RNase Complex)
Nuclear Exosome (RNase Complex)
3'-5'-RNA Exonuclease Activity
Nucleolar Exosome (RNase Complex)
Cytoplasmic Exosome (RNase Complex)
RNA Exonuclease Activity
SnRNA Metabolic Process
MRNA Metabolic Process
RNA 3'-end Processing
RNA Catabolic Process
RNA Binding
Nuclear-transcribed MRNA Catabolic Process
SnRNA Catabolic Process
Nuclear RNA Surveillance
CUT Catabolic Process
RNA Surveillance
Regulation Of Female Gonad Development
Regulation Of Telomere Maintenance Via Telomerase
RRNA Metabolic Process
Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
TRNA Surveillance
TRAMP-dependent TRNA Surveillance Pathway
Nuclear Polyadenylation-dependent RRNA Catabolic Process
MRNA Catabolic Process
U4 SnRNA 3'-end Processing
Identical Protein Binding
Regulation Of Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of Macromolecule Biosynthetic Process
Nucleolus
RRNA 3'-end Processing
Euchromatin
TRNA Decay
Nuclear MRNA Surveillance
Nucleoplasm
Negative Regulation Of Biosynthetic Process
Regulation Of Telomerase RNA Localization To Cajal Body
MDM2/MDM4 Family Protein Binding
DNA Deamination
Negative Regulation Of Metabolic Process
Nucleobase-containing Compound Catabolic Process
Response To Heat
Regulation Of DNA Biosynthetic Process
RRNA Processing
Negative Regulation Of Gene Expression
Maturation Of 5.8S RRNA
Regulation Of Cell Growth
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Fibroblast Apoptotic Process
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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