KNSTRN and CHMP1B

Number of citations of the paper that reports this interaction (PMID 16730941)
46

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KNSTRN	CHMP1B
Gene Name		kinetochore-localized astrin/SPAG5 binding protein	charged multivesicular body protein 1B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Nucleus Cytoplasm Microtubule Cytoskeleton Microtubule Plus-end Mitotic Spindle	Cytosol Late Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Protein Binding Protein Domain Specific Binding
	Biological Process	Mitotic Sister Chromatid Segregation Spindle Organization Chromosome Segregation Cell Division Regulation Of Attachment Of Spindle Microtubules To Kinetochore	Cytokinesis Cell Separation After Cytokinesis Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Establishment Of Protein Localization Regulation Of Mitotic Spindle Assembly
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CHMP1B CLU MAPK6 MPHOSPH6 MPP6 NUPR1 ZDHHC17	16 interactors: CHMP1A CHMP4B CHMP5 CNOT10 KNSTRN RAB11A RASSF7 SNRNP200 SPAST SSRP1 STAMBP SUCLG1 USP54 USP8 VPS4A VPS4B
Entrez ID		90417	57132
HPRD ID		12669	12106
Ensembl ID		ENSG00000128944	ENSG00000255112
Uniprot IDs		Q9Y448	Q7LBR1
PDB IDs			3EAB
Enriched GO Terms of Interacting Partners?		Maturation Of 5.8S RRNA Positive Regulation Of Tau-protein Kinase Activity Microglial Cell Proliferation Regulation Of Neuronal Signal Transduction Positive Regulation Of Neurofibrillary Tangle Assembly RRNA Processing RRNA Metabolic Process Central Nervous System Myelin Maintenance Intrinsic Apoptotic Signaling Pathway Ribosome Biogenesis Regulation Of Tau-protein Kinase Activity Negative Regulation Of Protein Homooligomerization Positive Regulation Of Inclusion Body Assembly Regulation Of Beta-amyloid Clearance Positive Regulation Of Beta-amyloid Formation Regulation Of Mitotic Spindle Assembly Protein Complex Assembly Negative Regulation Of Protein Oligomerization Negative Regulation Of Beta-amyloid Formation Regulation Of Spindle Assembly Regulation Of Female Gonad Development Ribonucleoprotein Complex Biogenesis Regulation Of Protein Complex Assembly Chaperone-mediated Protein Complex Assembly Microglial Cell Activation Regulation Of Mitotic Spindle Organization Negative Regulation Of Amyloid Precursor Protein Catabolic Process Apoptotic Signaling Pathway Glial Cell Proliferation Response To Misfolded Protein Regulation Of Beta-amyloid Formation Regulation Of Inclusion Body Assembly Reverse Cholesterol Transport Regulation Of Amyloid Precursor Protein Catabolic Process Cell Separation After Cytokinesis Central Nervous System Myelination Lipoprotein Transport Protein Transport Magnesium Ion Transport Establishment Of Protein Localization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage NcRNA Metabolic Process Mitotic Metaphase Plate Congression Regulation Of Protein Oligomerization Protein Palmitoylation Macrophage Activation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Release Of Cytochrome C From Mitochondria Metaphase Plate Congression Myelin Maintenance	Cell Separation After Cytokinesis Mitotic Metaphase Plate Congression Cell Division Mitotic Sister Chromatid Segregation Metaphase Plate Congression Sister Chromatid Segregation Establishment Of Chromosome Localization Mitotic Cell Cycle Process Mitotic Cell Cycle Regulation Of Mitotic Spindle Assembly Regulation Of Spindle Assembly Cytokinesis Chromosome Segregation Regulation Of Mitotic Spindle Organization Cell Cycle Process Regulation Of Microtubule Cytoskeleton Organization Mitotic Nuclear Division Regulation Of Microtubule-based Process Cell Cycle Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Budding Via Host ESCRT Complex Nucleus Organization Regulation Of Centrosome Duplication Viral Budding Regulation Of Centrosome Cycle Establishment Of Organelle Localization Chromosome Organization Organelle Localization Endosomal Transport Virion Assembly Regulation Of Cell Cycle Process Regulation Of Cell Division Regulation Of Cytoskeleton Organization Endosome Organization Regulation Of Mitotic Nuclear Division Mitotic Cytokinesis Regulation Of Mitotic Cell Cycle Organelle Organization Viral Life Cycle Positive Regulation Of Viral Release From Host Cell Cellular Macromolecule Catabolic Process Positive Regulation Of Viral Process Regulation Of Organelle Organization Vacuolar Transport Regulation Of Cell Cycle Membrane Budding Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion
Tagcloud ?		aneuploidy carcinomas chromatid cohesion concentrated correlate cutaneous discovery disrupt encodes encoding enhance hotspot kinetochore mutagenesis mutations notably occur precursors recurrent report scc sccs ser24phe signature squamous tumorigenesis tumors ultraviolet	aux1 auxin disorganized endosomal escrt gradients internalized lip5 lumenal meristems mislocalized multivesicular mvb mvbs pin1 pin2 pinformed1 protein1a resistant1 rudimentary seedling seedlings skd1 sorted stomata symmetry thaliana vacuolar
Tagcloud (Difference) ?		aneuploidy carcinomas chromatid cohesion concentrated correlate cutaneous discovery disrupt encodes encoding enhance hotspot kinetochore mutagenesis mutations notably occur precursors recurrent report scc sccs ser24phe signature squamous tumorigenesis tumors ultraviolet	aux1 auxin disorganized endosomal escrt gradients internalized lip5 lumenal meristems mislocalized multivesicular mvb mvbs pin1 pin2 pinformed1 protein1a resistant1 rudimentary seedling seedlings skd1 sorted stomata symmetry thaliana vacuolar
Tagcloud (Intersection) ?