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LHX4 and ZNF76
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
LHX4
ZNF76
Description
LIM homeobox 4
zinc finger protein 76
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleus
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Protein Binding
Zinc Ion Binding
Methyl-CpG Binding
Sequence-specific DNA Binding
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Protein Binding
Zinc Ion Binding
Sequence-specific DNA Binding
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Placenta Development
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Apoptotic Process
Motor Neuron Axon Guidance
Animal Organ Morphogenesis
Medial Motor Column Neuron Differentiation
Neuron Differentiation
Negative Regulation Of Apoptotic Process
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase III
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Regulation of expression of SLITs and ROBOs
Drugs
Diseases
Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS
Refractive error (
32231278
)
Height (
18391951
25282103
31562340
)
Plateletcrit (
32888494
)
Refractive error (
32231278
)
Interacting Genes
54 interacting genes:
ADAMTSL4
ARL2
AXIN1
BANP
BOD1L2
CDK3
CENPS-CORT
CHCHD2
CORO1B
DCAF10
DHRS1
DNAJB13
ERO1A
FDX2
GOLGA2
HNF1B
HOXC5
IFT172
IKZF1
INO80B
KLHL38
KRT38
KRT40
LDB2
LONRF1
MAPRE3
MRS2
MYOZ1
NFIC
NFIX
NRF1
ORC6
PARP11
POU1F1
QRICH1
SCAND1
SH2D1A
SNRNP25
SNRPA
SSX1
TCAP
TCF4
TP53BP2
TRAPPC6A
TRMT11
TSEN54
TSTD2
TXNDC5
UBQLN1
USP2
WASHC3
ZBTB2
ZNF354C
ZNF76
93 interacting genes:
ACAT2
ALOXE3
ANKRD37
ANTKMT
ATP5PO
BLZF1
BOLA2
BOLA2B
C10orf55
C22orf15
C3orf36
CCDC33
CEACAM6
CEP76
CSN3
DDIT4L
DISC1
ENKD1
EP300
EXOSC1
FAM228A
FAM90A1
FCRL4
FNDC8
FSD2
GIMAP6
GRAPL
HDAC1
HOMEZ
HUNK
IKZF3
KCTD9
KLF15
KPNA3
KRT40
KRT75
L3MBTL3
LAP3
LETM1
LHX3
LHX4
LHX6
LIN37
LIN54
LMO1
MAGEA6
MBD3L1
MBD5
MED19
MFAP1
MORN3
MRPL12
MTFR1L
MTUS2
MYL10
NEDD9
NRIP2
PIAS1
PMPCA
POGZ
PRKAR1B
RAB3IP
RALY
REL
RNF214
RPRD1A
RPS21
SCNM1
SLAIN1
SMAD1
SNAI2
SPANXN3
SPATA8
SPMIP10
STMN3
TASOR2
TBC1D22B
TBP
TEKT5
TGS1
TNNI1
USP54
USP6
USP7
VXN
WDR83
YPEL3
ZC2HC1C
ZC4H2
ZMYM6
ZNF420
ZNF526
ZNF623
Entrez ID
89884
7629
HPRD ID
03686
01929
Ensembl ID
ENSG00000121454
ENSG00000065029
Uniprot IDs
A0A0S2Z5S4
Q969G2
P36508
PDB IDs
5HOD
Enriched GO Terms of Interacting Partners
?
Protein Binding
Medial Motor Column Neuron Differentiation
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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