ZNF76 and GIMAP6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF76	GIMAP6
Description		zinc finger protein 76	GTPase, IMAP family member 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Nucleotide Binding GTPase Activity GTP Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase III Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Height ( 18391951 25282103 31562340) Plateletcrit ( 32888494) Refractive error ( 32231278)	Fibrinogen levels ( 28107422) HDL cholesterol levels ( 32203549) Multiple sclerosis ( 31604244)
Interacting Genes		93 interacting genes: ACAT2 ALOXE3 ANKRD37 ANTKMT ATP5PO BLZF1 BOLA2 BOLA2B C10orf55 C22orf15 C3orf36 CCDC33 CEACAM6 CEP76 CSN3 DDIT4L DISC1 ENKD1 EP300 EXOSC1 FAM228A FAM90A1 FCRL4 FNDC8 FSD2 GIMAP6 GRAPL HDAC1 HOMEZ HUNK IKZF3 KCTD9 KLF15 KPNA3 KRT40 KRT75 L3MBTL3 LAP3 LETM1 LHX3 LHX4 LHX6 LIN37 LIN54 LMO1 MAGEA6 MBD3L1 MBD5 MED19 MFAP1 MORN3 MRPL12 MTFR1L MTUS2 MYL10 NEDD9 NRIP2 PIAS1 PMPCA POGZ PRKAR1B RAB3IP RALY REL RNF214 RPRD1A RPS21 SCNM1 SLAIN1 SMAD1 SNAI2 SPANXN3 SPATA8 SPMIP10 STMN3 TASOR2 TBC1D22B TBP TEKT5 TGS1 TNNI1 USP54 USP6 USP7 VXN WDR83 YPEL3 ZC2HC1C ZC4H2 ZMYM6 ZNF420 ZNF526 ZNF623	4 interacting genes: APP DDIT3 GABARAPL2 ZNF76
Entrez ID		7629	474344
HPRD ID		01929	13576
Ensembl ID		ENSG00000065029	ENSG00000133561
Uniprot IDs		P36508	B4DH95 Q6P9H5
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Medial Motor Column Neuron Differentiation	Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress Acetylcholine Receptor Activator Activity Negative Regulation Of Canonical Wnt Signaling Pathway Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Negative Regulation Of Wnt Signaling Pathway Regulation Of Response To Calcium Ion Positive Regulation Of Neuron Apoptotic Process Regulation Of Type II Interferon Production Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Positive Regulation Of Apoptotic Signaling Pathway Growth Cone Filopodium Regulation Of Response To Endoplasmic Reticulum Stress Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Intrinsic Apoptotic Signaling Pathway In Response To Nitrosative Stress Negative Regulation Of Determination Of Dorsal Identity CHOP-C/EBP Complex CHOP-ATF4 Complex CHOP-ATF3 Complex Diaphragm Contraction Vascular Associated Smooth Muscle Cell Migration Regulation Of Intrinsic Apoptotic Signaling Pathway Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Developmental Maturation Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Involuntary Skeletal Muscle Contraction Cellular Response To Nitrosative Stress Response To Starvation Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon GDF15-GFRAL Signaling Pathway Regulation Of Canonical Wnt Signaling Pathway Regulation Of Spontaneous Synaptic Transmission
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