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LHX4 and FDX1L
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
LHX4
FDX1L
Gene Name
LIM homeobox 4
ferredoxin 1-like
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Mitochondrial Matrix
Molecular Function
Zinc Ion Binding
Sequence-specific DNA Binding
Electron Carrier Activity
Metal Ion Binding
2 Iron, 2 Sulfur Cluster Binding
Biological Process
Placenta Development
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Motor Neuron Axon Guidance
Organ Morphogenesis
Medial Motor Column Neuron Differentiation
Negative Regulation Of Apoptotic Process
C21-steroid Hormone Biosynthetic Process
Xenobiotic Metabolic Process
Steroid Metabolic Process
Sterol Metabolic Process
Small Molecule Metabolic Process
Oxidation-reduction Process
Pathways
Defective CYP2R1 causes Rickets vitamin D-dependent 1B (VDDR1B)
Metabolism of lipids and lipoproteins
Pregnenolone biosynthesis
Mitochondrial iron-sulfur cluster biogenesis
Metabolic disorders of biological oxidation enzymes
Phase 1 - Functionalization of compounds
Defective CYP27B1 causes Rickets vitamin D-dependent 1A (VDDR1A)
Defective CYP26C1 causes Focal facial dermal dysplasia 4 (FFDD4)
Electron transport from NADPH to Ferredoxin
Defective CYP2U1 causes Spastic paraplegia 56, autosomal recessive (SPG56)
Cytochrome P450 - arranged by substrate type
Endogenous sterols
Biological oxidations
Defective FMO3 causes Trimethylaminuria (TMAU)
Defective TBXAS1 causes Ghosal hematodiaphyseal dysplasia (GHDD)
Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)
Defective CYP27A1 causes Cerebrotendinous xanthomatosis (CTX)
Defective CYP11B1 causes Adrenal hyperplasia 4 (AH4)
Defective CYP26B1 causes Radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA)
Defective CYP1B1 causes Glaucoma
Metabolism of steroid hormones and vitamin D
Defective CYP17A1 causes Adrenal hyperplasia 5 (AH5)
Defective CYP7B1 causes Spastic paraplegia 5A, autosomal recessive (SPG5A) and Congenital bile acid synthesis defect 3 (CBAS3)
Defective CYP19A1 causes Aromatase excess syndrome (AEXS)
Defective CYP4F22 causes Ichthyosis, congenital, autosomal recessive 5 (ARCI5)
Defective CYP24A1 causes Hypercalcemia, infantile (HCAI)
Defective MAOA causes Brunner syndrome (BRUNS)
Defective CYP11B2 causes Corticosterone methyloxidase 1 deficiency (CMO-1 deficiency)
Defective CYP21A2 causes Adrenal hyperplasia 3 (AH3)
Drugs
Diseases
GWAS
Protein-Protein Interactions
12 interactors:
CHCHD2
FDX1L
IFT172
ISL1
LDB2
LONRF1
ORC6
SH2D1A
SNRNP25
SSX1
TXNDC5
USP2
2 interactors:
APP
LHX4
Entrez ID
89884
112812
HPRD ID
03686
14465
Ensembl ID
ENSG00000267673
Uniprot IDs
Q969G2
Q6P4F2
Q8N8B8
PDB IDs
2Y5C
Enriched GO Terms of Interacting Partners
?
Spinal Cord Motor Neuron Differentiation
Ventral Spinal Cord Development
Cell Differentiation In Spinal Cord
Synaptic Growth At Neuromuscular Junction
Medial Motor Column Neuron Differentiation
Collateral Sprouting In Absence Of Injury
Axon Guidance
Collateral Sprouting
Axon Midline Choice Point Recognition
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Axonogenesis
Axon Choice Point Recognition
Axon Development
Somatic Motor Neuron Differentiation
Cell Morphogenesis Involved In Neuron Differentiation
Chemotaxis
Neuron Remodeling
Neuron Projection Morphogenesis
Cell Morphogenesis Involved In Differentiation
Neuron Projection Development
Cell Projection Morphogenesis
Cell Part Morphogenesis
Cellular Copper Ion Homeostasis
Neuron Development
Central Nervous System Development
Copper Ion Homeostasis
Suckling Behavior
Cell Morphogenesis
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Neuron Differentiation
Cell Projection Organization
Neuron Maturation
MRNA Polyadenylation
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Mating Behavior
Motor Neuron Axon Guidance
Locomotion
Endoplasmic Reticulum Calcium Ion Homeostasis
Neuron Recognition
RNA Polyadenylation
Reproductive Process
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Ionotropic Glutamate Receptor Signaling Pathway
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Spinal Cord Motor Neuron Differentiation
Regulation Of Cell Cycle G2/M Phase Transition
Movement Of Cell Or Subcellular Component
Axon Cargo Transport
Mating
Neuromuscular Junction Development
Generation Of Neurons
Positive Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle Phase Transition
Tagcloud
?
add
besides
clinician
concern
congenital
correct
costly
deviation
disturb
emphasis
genetics
ghr
ghrhr
height
hesx1
hypothalamus
igfr
know
lhx3
manifestation
normality
nutrition
ones
origins
pituitary
pou1f1
prop1
psychosocial
stature
Tagcloud (Difference)
?
add
besides
clinician
concern
congenital
correct
costly
deviation
disturb
emphasis
genetics
ghr
ghrhr
height
hesx1
hypothalamus
igfr
know
lhx3
manifestation
normality
nutrition
ones
origins
pituitary
pou1f1
prop1
psychosocial
stature
Tagcloud (Intersection)
?