LHX4 and BOD1L2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LHX4	BOD1L2
Description		LIM homeobox 4	biorientation of chromosomes in cell division 1 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Chromosome, Centromeric Region Kinetochore Chromosome Cytoplasm Centrosome Cytoskeleton
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Methyl-CpG Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Placenta Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Apoptotic Process Motor Neuron Axon Guidance Animal Organ Morphogenesis Medial Motor Column Neuron Differentiation Neuron Differentiation Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II	Cell Division
Pathways		Regulation of expression of SLITs and ROBOs
Drugs
Diseases		Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS		Refractive error ( 32231278)	Diverticular disease ( 30177863)
Interacting Genes		54 interacting genes: ADAMTSL4 ARL2 AXIN1 BANP BOD1L2 CDK3 CENPS-CORT CHCHD2 CORO1B DCAF10 DHRS1 DNAJB13 ERO1A FDX2 GOLGA2 HNF1B HOXC5 IFT172 IKZF1 INO80B KLHL38 KRT38 KRT40 LDB2 LONRF1 MAPRE3 MRS2 MYOZ1 NFIC NFIX NRF1 ORC6 PARP11 POU1F1 QRICH1 SCAND1 SH2D1A SNRNP25 SNRPA SSX1 TCAP TCF4 TP53BP2 TRAPPC6A TRMT11 TSEN54 TSTD2 TXNDC5 UBQLN1 USP2 WASHC3 ZBTB2 ZNF354C ZNF76	5 interacting genes: CRX LHX4 MEOX2 PRKAR1B TRAF2
Entrez ID		89884	284257
HPRD ID		03686
Ensembl ID		ENSG00000121454	ENSG00000228075
Uniprot IDs		A0A0S2Z5S4 Q969G2	Q8IYS8
PDB IDs		5HOD
Enriched GO Terms of Interacting Partners?			DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding TORC2 Complex Disassembly TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Medial Motor Column Neuron Differentiation Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Leucine Zipper Domain Binding Chromatin Segment Specification Somite Development Somite Specification CAMP-dependent Protein Kinase Complex CAMP-dependent Protein Kinase Regulator Activity Regulation Of Synaptic Vesicle Cycle Positive Regulation Of Fear Response Protein Kinase A Catalytic Subunit Binding CAMP-dependent Protein Kinase Inhibitor Activity Sphingolipid Binding Thioesterase Binding TORC2 Signaling CD40 Receptor Complex Cellular Response To Nitric Oxide CD40 Signaling Pathway Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of JUN Kinase Activity IRE1-TRAF2-ASK1 Complex Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway CD27 Signaling Pathway Mitogen-activated Protein Kinase Kinase Kinase Binding Tumor Necrosis Factor Binding Tumor Necrosis Factor Receptor Superfamily Binding Interleukin-17-mediated Signaling Pathway Tumor Necrosis Factor Receptor Superfamily Complex Cellular Response To Reactive Nitrogen Species CAMP Binding Response To Nitric Oxide Programmed Necrotic Cell Death Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Sequence-specific DNA Binding Positive Regulation Of Long-term Synaptic Potentiation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?