TGOLN2

Description		trans-golgi network protein 2
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GO Annotations	Cellular Component	Nucleoplasm Endosome Endoplasmic Reticulum Lumen Golgi Apparatus Trans-Golgi Network Plasma Membrane Membrane Transport Vesicle Trans-Golgi Network Transport Vesicle Clathrin-coated Endocytic Vesicle Membrane
	Molecular Function	Protein Binding
	Biological Process
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Golgi Associated Vesicle Biogenesis Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549)
Interacting Genes		11 interacting genes: AP1M1 AP1M2 AP2M1 AP3M1 AP4M1 CRYAA ITGB1 KRTAP10-9 PPP1R9A PPP1R9B PRKD2
Entrez ID		10618
HPRD ID		04343
Ensembl ID		ENSG00000152291
Uniprot IDs		A0A5F9UY30 O43493
PDB IDs		6YAF
Enriched GO Terms of Interacting Partners?		Clathrin Adaptor Complex Clathrin Adaptor Activity Receptor Internalization Postsynaptic Neurotransmitter Receptor Internalization Cytoplasmic Vesicle Intracellular Protein Transport Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Actin Filament Organization Filopodium AP-1 Adaptor Complex Vesicle-mediated Transport Trans-Golgi Network Membrane Regulation Of Protein Localization To Plasma Membrane Melanosome Assembly Lysosomal Membrane Dendritic Spine Platelet Dense Granule Organization Regulation Of Protein Localization To Cell Periphery Plasma Membrane Bounded Cell Projection Synapse Regulation Of Protein Localization To Membrane Receptor-mediated Endocytosis Establishment Of Localization In Cell Cytoplasmic Vesicle Membrane Protein Targeting To Lysosome Supramolecular Fiber Organization Cellular Component Assembly Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Clathrin-coated Vesicle Membrane Regulation Of Cellular Localization Melanosome Organization Pigment Granule Organization Protein Targeting Protein Transport Intracellular Protein Localization Protein Targeting To Vacuole Intracellular Transport Myoblast Fate Specification Integrin Alpha7-beta1 Complex Protein Localization To Lysosome Cortical Actin Cytoskeleton Positive Regulation Of Protein Localization To Actin Cortical Patch Dendritic Spine Neck Cytoplasmic Side Of Dendritic Spine Plasma Membrane Establishment Of Protein Localization Establishment Of Protein Localization To Vacuole Positive Regulation Of Protein Localization To Plasma Membrane Secretory Granule Organization Golgi Apparatus Vesicle Organization
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