TGOLN2 and PPP1R9B

Number of citations of the paper that reports this interaction (PubMedID 10514494)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		TGOLN2	PPP1R9B
Description		trans-golgi network protein 2	protein phosphatase 1 regulatory subunit 9B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endosome Endoplasmic Reticulum Lumen Golgi Apparatus Trans-Golgi Network Plasma Membrane Membrane Transport Vesicle Trans-Golgi Network Transport Vesicle Clathrin-coated Endocytic Vesicle Membrane	Protein Phosphatase Type 1 Complex Nucleus Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Adherens Junction Postsynaptic Density Actin Cytoskeleton Membrane Lamellipodium Filopodium Dendrite Growth Cone Cortical Actin Cytoskeleton Ruffle Membrane Dendritic Spine Membrane Cell Projection Neuronal Cell Body Dendritic Spine Dendritic Spine Neck Dendritic Spine Head Synapse Anchoring Junction Spine Apparatus Extrinsic Component Of Postsynaptic Membrane Glutamatergic Synapse Plasma Membrane Bounded Cell Projection Cytoplasmic Side Of Dendritic Spine Plasma Membrane
	Molecular Function	Protein Binding	Actin Binding Protein Kinase Activity Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 1 Binding Kinase Binding D2 Dopamine Receptor Binding Transmembrane Transporter Binding Protein-containing Complex Binding Actin Filament Binding
	Biological Process		Regulation Of Cell Growth By Extracellular Stimulus Response To Amphetamine Developmental Process Involved In Reproduction Actin Filament Organization Regulation Of Exit From Mitosis Nervous System Development Learning RNA Splicing Response To Xenobiotic Stimulus Dendrite Development Cell Migration Calcium-mediated Signaling Hippocampus Development Cerebral Cortex Development Actin Filament Depolymerization Cell Differentiation Negative Regulation Of Cell Growth Neuron Projection Development Response To Estradiol Response To Prostaglandin E Response To Nicotine Response To Immobilization Stress Regulation Of Cell Population Proliferation Response To Amino Acid Filopodium Assembly Response To Steroid Hormone Regulation Of Cell Cycle Male Mating Behavior Reproductive System Development Cellular Response To Morphine Cellular Response To Epidermal Growth Factor Stimulus Cellular Response To Estradiol Stimulus Cellular Response To Xenobiotic Stimulus Regulation Of Postsynapse Assembly Cellular Response To Peptide Positive Regulation Of Protein Localization To Plasma Membrane Protein Localization To Actin Cytoskeleton Positive Regulation Of Protein Localization Positive Regulation Of Protein Localization To Actin Cortical Patch Response To Kainic Acid Response To L-phenylalanine Derivative Protein Localization To Cell Periphery Regulation Of Opioid Receptor Signaling Pathway
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Golgi Associated Vesicle Biogenesis Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549)	Platelet distribution width ( 32888494) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		11 interacting genes: AP1M1 AP1M2 AP2M1 AP3M1 AP4M1 CRYAA ITGB1 KRTAP10-9 PPP1R9A PPP1R9B PRKD2	29 interacting genes: ACTA1 ACTN2 ADRA1A ADRA1B ADRA2A ADRA2B ADRA2C CCKAR CCKBR CDKN2A CHRM3 DCX DRD2 ITGB8 LRRC7 MAPK1 MECOM PPP1CA PPP1R2 PPP1R9A PRKACA RB1 RBL1 RBL2 RGS2 RPS6KB1 SHANK3 TGOLN2 TIAM1
Entrez ID		10618	84687
HPRD ID		04343	04506
Ensembl ID		ENSG00000152291	ENSG00000108819
Uniprot IDs		A0A5F9UY30 O43493	Q96SB3
PDB IDs		6YAF
Enriched GO Terms of Interacting Partners?		Clathrin Adaptor Complex Clathrin Adaptor Activity Receptor Internalization Postsynaptic Neurotransmitter Receptor Internalization Cytoplasmic Vesicle Intracellular Protein Transport Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Actin Filament Organization Filopodium AP-1 Adaptor Complex Vesicle-mediated Transport Trans-Golgi Network Membrane Regulation Of Protein Localization To Plasma Membrane Melanosome Assembly Lysosomal Membrane Dendritic Spine Platelet Dense Granule Organization Regulation Of Protein Localization To Cell Periphery Plasma Membrane Bounded Cell Projection Synapse Regulation Of Protein Localization To Membrane Receptor-mediated Endocytosis Establishment Of Localization In Cell Cytoplasmic Vesicle Membrane Protein Targeting To Lysosome Supramolecular Fiber Organization Cellular Component Assembly Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Clathrin-coated Vesicle Membrane Regulation Of Cellular Localization Melanosome Organization Pigment Granule Organization Protein Targeting Protein Transport Intracellular Protein Localization Protein Targeting To Vacuole Intracellular Transport Myoblast Fate Specification Integrin Alpha7-beta1 Complex Protein Localization To Lysosome Cortical Actin Cytoskeleton Positive Regulation Of Protein Localization To Actin Cortical Patch Dendritic Spine Neck Cytoplasmic Side Of Dendritic Spine Plasma Membrane Establishment Of Protein Localization Establishment Of Protein Localization To Vacuole Positive Regulation Of Protein Localization To Plasma Membrane Secretory Granule Organization Golgi Apparatus Vesicle Organization	Adrenergic Receptor Activity Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adrenergic Receptor Signaling Pathway Regulation Of Muscle Contraction Regulation Of Smooth Muscle Contraction Negative Regulation Of Catecholamine Secretion Alpha2-adrenergic Receptor Activity Regulation Of Muscle System Process Intracellular Signaling Cassette Regulation Of Blood Circulation G Protein-coupled Receptor Activity Signal Transduction Regulation Of System Process Regulation Of Cell Communication Regulation Of Signaling Regulation Of Lipid Kinase Activity Intracellular Signal Transduction Negative Regulation Of Epinephrine Secretion Regulation Of Vasoconstriction Negative Regulation Of Norepinephrine Secretion Epinephrine Binding Regulation Of Amine Transport System Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Catecholamine Secretion Regulation Of Biological Quality Regulation Of MAPK Cascade Regulation Of Signal Transduction Regulation Of Norepinephrine Secretion Modulation Of Chemical Synaptic Transmission Positive Regulation Of Muscle Contraction Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Developmental Process Phospholipase C-activating Adrenergic Receptor Signaling Pathway Cholecystokinin Receptor Activity Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Hormone Secretion Dendritic Spine Positive Regulation Of Signal Transduction Regulation Of Tube Size Blood Vessel Diameter Maintenance Regulation Of Intracellular Signal Transduction Alpha1-adrenergic Receptor Activity Cholecystokinin Signaling Pathway Regulation Of Insulin Secretion ERBB Signaling Pathway Positive Regulation Of Cellular Component Organization
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