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TBC1D17 and ASCC2
Number of citations of the paper that reports this interaction (PubMedID
16169070
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
TBC1D17
ASCC2
Description
TBC1 domain family member 17
activating signal cointegrator 1 complex subunit 2
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Endosome
Autophagosome
Cytosol
Cytoplasmic Vesicle
Recycling Endosome
Nucleus
Nucleoplasm
Nuclear Speck
Cytosolic Ribosome
RQC-trigger Complex
DNA Repair Complex
Molecular Function
GTPase Activator Activity
Protein Binding
Protein Binding
Ubiquitin Binding
K63-linked Polyubiquitin Modification-dependent Protein Binding
Biological Process
Autophagy
Protein Transport
Retrograde Transport, Endosome To Golgi
Regulation Of Cilium Assembly
DNA Replication
DNA Repair
DNA Alkylation Repair
Regulation Of DNA-templated Transcription
DNA Damage Response
Ribosome Disassembly
Rescue Of Stalled Ribosome
Ribosome-associated Ubiquitin-dependent Protein Catabolic Process
Pathways
TBC/RABGAPs
ALKBH3 mediated reversal of alkylation damage
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs
Diseases
GWAS
Bipolar disorder or attention deficit hyperactivity disorder (
27890468
)
Crohn's disease (
28067908
)
Hemoglobin levels (
32327693
)
IgA levels (
28628107
)
Immature fraction of reticulocytes (
27863252
)
Inflammatory bowel disease (
28067908
)
Mean corpuscular hemoglobin concentration (
32888494
)
Refractive error (
32231278
)
Spleen volume (
34128465
)
Telomere length (
24478790
)
Tonsillectomy (
27941131
)
Type 2 diabetes (
30297969
)
Type 2 diabetes (adjusted for BMI) (
29632382
)
Interacting Genes
20 interacting genes:
ASCC2
CALCOCO1
CCT5
CDKN2D
DHX29
FBL
GABARAPL1
GPS1
GTF3C1
MAP1LC3A
MAP1LC3B
NIPSNAP1
OPTN
RAB1A
RAB5A
RAB5B
RAB5C
SLC1A5
TAX1BP1
UBC
41 interacting genes:
ASS1
CKAP4
CUTC
DEAF1
EEF1D
ELAC2
FAF1
FBP1
FUNDC2
GADD45A
GFER
GNL3
GTF3C1
IGSF9
IMMT
KATNAL1
KDM1A
LPL
MAP3K1
MED31
MYH9
OLA1
PCBD2
PIK3CD
PIN4
PJA1
POLA2
POLDIP2
PRPF18
RADIL
RNF11
RPA1
RPLP1
SASH1
SMURF1
SNRPB
SNW1
TBC1D17
TRIP4
UBC
URM1
Entrez ID
79735
84164
HPRD ID
15471
16515
Ensembl ID
ENSG00000104946
ENSG00000100325
Uniprot IDs
Q9HA65
Q9H1I8
PDB IDs
2DI0
6YXQ
Enriched GO Terms of Interacting Partners
?
Mitophagy
Autophagy
Autophagy Of Mitochondrion
Autophagosome
Melanosome
Plasma Membrane To Endosome Transport
Cellular Response To Nitrogen Starvation
Endomembrane System
Phosphatidylethanolamine Binding
Macroautophagy
G Protein Activity
Autophagosome Assembly
Autophagosome Organization
Autophagosome Maturation
Autophagosome Membrane
Vacuole Organization
Endocytic Vesicle
GDP Binding
Catabolic Process
Extracellular Exosome
Cytoplasmic Vesicle
Ubiquitin Protein Ligase Binding
Phospholipid Binding
K63-linked Polyubiquitin Modification-dependent Protein Binding
GTPase Activity
Early Endosome
Import Into Cell
Microtubule
Protein-containing Complex Disassembly
GTP Binding
Beta-tubulin Binding
U6 SnRNA 2'-O-ribose Methyltransferase Activity
Organelle Assembly
Organelle Organization
Cellular Response To Starvation
Organelle Membrane
Endosome
Endocytosis
Early Endosome Membrane
Protein-macromolecule Adaptor Activity
Response To Nutrient Levels
Histone H2AQ104 Methyltransferase Activity
JNK Cascade
Glutamine Secretion
Protein Localization To Phagocytic Vesicle
Response To Starvation
Cyclin D2-CDK4 Complex
Box C/D Sno(s)RNA 3'-end Processing
Intracellular Protein Transport
Protein Localization To Early Endosome
Macromolecule Metabolic Process
Nucleoplasm
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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