TBC1D17 and CALCOCO1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TBC1D17	CALCOCO1
Description		TBC1 domain family member 17	calcium binding and coiled-coil domain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Autophagosome Cytosol Cytoplasmic Vesicle Recycling Endosome	Chromatin Nucleus Cytoplasm Cytosol
	Molecular Function	GTPase Activator Activity Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Beta-catenin Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Autophagy Protein Transport Retrograde Transport, Endosome To Golgi Regulation Of Cilium Assembly	Signal Transduction Positive Regulation Of Gene Expression Wnt Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways		TBC/RABGAPs
Drugs
Diseases
GWAS			Panic disorder ( 19165232) Toenail selenium levels ( 25343990) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		20 interacting genes: ASCC2 CALCOCO1 CCT5 CDKN2D DHX29 FBL GABARAPL1 GPS1 GTF3C1 MAP1LC3A MAP1LC3B NIPSNAP1 OPTN RAB1A RAB5A RAB5B RAB5C SLC1A5 TAX1BP1 UBC	37 interacting genes: APP APTX ARNT BFSP2 CEP19 CREBBP CRYBA2 CTNNBL1 CWF19L2 CYTH3 DUSP13B ENKD1 EP300 FAM161A FOSL1 FXR1 GABARAPL1 GABARAPL2 GRIK2 IPP ISOC1 KRT15 MAPK1 MYH6 NDC80 NEDD4 PCBD1 POLR2A PRKAA2 RNF8 SH3GL3 SHANK3 SMURF1 SRPK2 TBC1D15 TBC1D17 ZMAT2
Entrez ID		79735	57658
HPRD ID		15471	13868
Ensembl ID		ENSG00000104946	ENSG00000012822
Uniprot IDs		Q9HA65	Q9P1Z2
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitophagy Autophagy Autophagy Of Mitochondrion Autophagosome Melanosome Plasma Membrane To Endosome Transport Cellular Response To Nitrogen Starvation Endomembrane System Phosphatidylethanolamine Binding Macroautophagy G Protein Activity Autophagosome Assembly Autophagosome Organization Autophagosome Maturation Autophagosome Membrane Vacuole Organization Endocytic Vesicle GDP Binding Catabolic Process Extracellular Exosome Cytoplasmic Vesicle Ubiquitin Protein Ligase Binding Phospholipid Binding K63-linked Polyubiquitin Modification-dependent Protein Binding GTPase Activity Early Endosome Import Into Cell Microtubule Protein-containing Complex Disassembly GTP Binding Beta-tubulin Binding U6 SnRNA 2'-O-ribose Methyltransferase Activity Organelle Assembly Organelle Organization Cellular Response To Starvation Organelle Membrane Endosome Endocytosis Early Endosome Membrane Protein-macromolecule Adaptor Activity Response To Nutrient Levels Histone H2AQ104 Methyltransferase Activity JNK Cascade Glutamine Secretion Protein Localization To Phagocytic Vesicle Response To Starvation Cyclin D2-CDK4 Complex Box C/D Sno(s)RNA 3'-end Processing Intracellular Protein Transport Protein Localization To Early Endosome	Cytoplasm Regulation Of Long-term Neuronal Synaptic Plasticity Organelle Assembly Regulation Of Glycolytic Process Histone H3K27 Acetyltransferase Activity Regulation Of Neuronal Synaptic Plasticity Regulation Of Carbohydrate Catabolic Process Positive Regulation Of Glycolytic Process Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Peptide Lactyltransferase (CoA-dependent) Activity Cellular Response To Nutrient Levels Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Nucleoplasm Intracellular Signal Transduction Ciliary Basal Body Positive Regulation Of ATP Metabolic Process Regulation Of Synaptic Plasticity Regulation Of Tubulin Deacetylation Regulation Of Long-term Synaptic Potentiation Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Generation Of Precursor Metabolites And Energy Cellular Response To Nitrogen Starvation Regulation Of Protein Deacetylation Positive Regulation Of Synaptic Transmission Negative Regulation Of Long-term Synaptic Potentiation N-terminal Protein Amino Acid Acetylation Cellular Response To Stress Peptidyl-lysine Acetylation Intracellular Signaling Cassette Positive Regulation Of Small Molecule Metabolic Process Cytosol Damaged DNA Binding Prp19 Complex Phosphatidylethanolamine Binding Regulation Of Plasma Membrane Bounded Cell Projection Organization Positive Regulation Of Neuron Apoptotic Process Regulation Of Cellular Response To Heat Ubiquitin Protein Ligase Binding Regulation Of Cell Projection Organization Chromatin Binding Organelle Organization Scaffold Protein Binding Regulation Of Synaptic Transmission, Glutamatergic Response To Nutrient Levels GABA Receptor Binding Regulation Of Small Molecule Metabolic Process Cellular Response To Starvation
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