AZI2 and APBA3

Number of citations of the paper that reports this interaction (PMID 21903422)
33

Data Source:
BioGRID (pull down)

		AZI2	APBA3
Gene Name		5-azacytidine induced 2	amyloid beta (A4) precursor protein-binding, family A, member 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Beta-amyloid Binding Enzyme Inhibitor Activity Protein Binding Enzyme Binding
	Biological Process	Mitotic Cell Cycle I-kappaB Kinase/NF-kappaB Signaling Interferon-alpha Production Interferon-gamma Production Interleukin-6 Production Tumor Necrosis Factor Production T Cell Activation Dendritic Cell Proliferation Dendritic Cell Differentiation	In Utero Embryonic Development Synaptic Transmission Regulation Of Gene Expression Protein Transport Negative Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: APBA3 IKBKE MIB1 MTPAP N4BP1 ODC1 RNF31 TBK1 TICAM1 TRAF3 TXLNA	6 interactors: APP AZI2 BCR EGFR TANK TBKBP1
Entrez ID		64343	9546
HPRD ID		10577	05038
Ensembl ID		ENSG00000163512	ENSG00000011132
Uniprot IDs		Q9H6S1	O96018
PDB IDs			2YT7 2YT8
Enriched GO Terms of Interacting Partners?		TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Regulation Of Type I Interferon Production Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Regulation Of Interferon-beta Production Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Type I Interferon Production Positive Regulation Of Innate Immune Response Immune Response-regulating Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Innate Immune Response Positive Regulation Of Interferon-beta Biosynthetic Process Positive Regulation Of Immune Response Regulation Of Immune Response Positive Regulation Of Immune System Process Positive Regulation Of Interferon-beta Production Regulation Of Cytokine Production Negative Regulation Of Cytokine Production Regulation Of Immune System Process Immune System Process Response To Virus Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Cytokine Biosynthetic Process Putrescine Biosynthetic Process From Ornithine Positive Regulation Of Type I Interferon Production CD40 Signaling Pathway Regulation Of Cytokine Biosynthetic Process Leukocyte Activation Protein Linear Polyubiquitination Putrescine Biosynthetic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Dendritic Cell Proliferation Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Protein Ubiquitination Immune Response Protein Modification By Small Protein Conjugation Defense Response Defense Response To Virus Cell Activation Ornithine Metabolic Process Response To Other Organism	Innate Immune Response Immune System Process I-kappaB Kinase/NF-kappaB Signaling Immune Response Defense Response Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Regulation Of ERBB Signaling Pathway Tumor Necrosis Factor Production Alkanesulfonate Metabolic Process Cell Activation Neuromuscular Process Synaptic Growth At Neuromuscular Junction Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Intracellular Signal Transduction Brain Development Head Development Interferon-alpha Production Collateral Sprouting In Absence Of Injury Regulation Of Immune Response Interleukin-6 Production Activation Of Phospholipase A2 Activity Regulation Of Cell Cycle Regulation Of Peptidyl-tyrosine Phosphorylation Protein Autophosphorylation Positive Regulation Of Phospholipase A2 Activity Collateral Sprouting Axon Midline Choice Point Recognition Dendritic Cell Proliferation Central Nervous System Development Response To Cobalamin Response To UV-A Negative Regulation Of Neutrophil Degranulation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Hydrolase Activity Response To Hydroxyisoflavone Regulation Of Neutrophil Degranulation Negative Regulation Of Neutrophil Activation Axon Choice Point Recognition Response To Stimulus Learning Or Memory Positive Regulation Of Superoxide Anion Generation Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Inflammatory Response Peptidyl-tyrosine Phosphorylation Neurological System Process Positive Regulation Of Cell Cycle Cognition Cell Adhesion
Tagcloud ?		activator ag azacytidine cdcs clarified critical csf cycling dcs defects dendritic dispensable efficiency efficient generation gm ifn ifns immunization marrow member nap1 none production reciprocally tank tbk1 tbkbp1 tnfr	a4 additive aging amyloid apbb1 aplp1 apolipoprotein c57bl clues dysregulation elusive fe65 hippocampal hypertension hypertensive impairments m1 manifestation maze mint3 mo muscarinic object precursor predisposes secretases signature tauopathy wk
Tagcloud (Difference) ?		activator ag azacytidine cdcs clarified critical csf cycling dcs defects dendritic dispensable efficiency efficient generation gm ifn ifns immunization marrow member nap1 none production reciprocally tank tbk1 tbkbp1 tnfr	a4 additive aging amyloid apbb1 aplp1 apolipoprotein c57bl clues dysregulation elusive fe65 hippocampal hypertension hypertensive impairments m1 manifestation maze mint3 mo muscarinic object precursor predisposes secretases signature tauopathy wk
Tagcloud (Intersection) ?