AZI2 and MTPAP

Number of citations of the paper that reports this interaction (PubMedID 21903422)
55

Data Source:
BioGRID (pull down)

		AZI2	MTPAP
Description		5-azacytidine induced 2	mitochondrial poly(A) polymerase
Image
GO Annotations	Cellular Component	Cytoplasm Serine/threonine Protein Kinase Complex	Nucleoplasm Cytoplasm Mitochondrion
	Molecular Function	Protein Binding	Nucleotide Binding Magnesium Ion Binding UTP Binding RNA Binding Protein Binding ATP Binding Transferase Activity Nucleotidyltransferase Activity Manganese Ion Binding Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Poly(A) RNA Polymerase Activity
	Biological Process	Mitotic Cell Cycle T Cell Activation Negative Regulation Of Canonical NF-kappaB Signal Transduction Dendritic Cell Proliferation Defense Response To Virus Type I Interferon-mediated Signaling Pathway Dendritic Cell Differentiation	Mitochondrial RNA 3'-end Processing MRNA Processing RNA 3'-end Processing Histone MRNA Catabolic Process Mitochondrial MRNA Polyadenylation
Pathways			Mitochondrial mRNA modification
Drugs
Diseases
GWAS		Cognitive decline (age-related) ( 28078323)	Paclitaxel disposition in epithelial ovarian cancer ( 29367611)
Interacting Genes		16 interacting genes: APBA3 FAM107A GABARAP GABARAPL1 GABARAPL2 IKBKE MIB1 MTPAP N4BP1 RB1CC1 RNF31 TAX1BP1 TBK1 TICAM1 TRAF3 TXLNA	5 interacting genes: AZI2 CALCOCO2 CLK1 DMRTB1 TBK1
Entrez ID		64343	55149
HPRD ID		10577	15097
Ensembl ID		ENSG00000163512	ENSG00000107951
Uniprot IDs		Q9H6S1	Q9NVV4
PDB IDs		5EP6 5Z7G 5Z7L 7EA2 7EA7	3PQ1
Enriched GO Terms of Interacting Partners?		Autophagosome Cell Surface Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Cellular Response To Nitrogen Starvation Ubiquitin Protein Ligase Binding Regulation Of Canonical NF-kappaB Signal Transduction Cell Surface Pattern Recognition Receptor Signaling Pathway Autophagy Autophagosome Membrane Macroautophagy Phosphatidylethanolamine Binding GABA Receptor Binding Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Cytoplasm Autophagy Of Mitochondrion Serine/threonine Protein Kinase Complex Activation Of Innate Immune Response Positive Regulation Of Type I Interferon Production Activation Of Immune Response Autophagosome Assembly Regulation Of Innate Immune Response Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Defense Response Autophagosome Organization Response To Other Organism Cellular Response To Nutrient Levels Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Defense Response Defense Response To Virus Regulation Of Type I Interferon Production Positive Regulation Of Innate Immune Response Beta-tubulin Binding Response To External Biotic Stimulus Defense Response Regulation Of Immune Response Immune System Process Response To Stress Immune Response-activating Signaling Pathway Autophagosome Maturation Pattern Recognition Receptor Signaling Pathway Type I Interferon-mediated Signaling Pathway Innate Immune Response Vacuole Organization Positive Regulation Of Autophagy Positive Regulation Of Immune Response Innate Immune Response-activating Signaling Pathway Cell Surface Receptor Signaling Pathway Mitophagy Regulation Of Interferon-beta Production Response To Virus	Dendritic Cell Proliferation Serine/threonine Protein Kinase Complex Protein Serine/threonine Kinase Activity Protein Serine Kinase Activity Type I Interferon-mediated Signaling Pathway Interferon-mediated Signaling Pathway Protein Kinase Activity Positive Regulation Of Macroautophagy Mononuclear Cell Proliferation Kinase Activity Leukocyte Proliferation Macroautophagy Positive Regulation Of Autophagy Regulation Of Macroautophagy Xenophagy Positive Regulation Of Autophagosome Maturation Positive Regulation Of Xenophagy Positive Regulation Of TORC2 Signaling
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?