RAD54L2 and LCE1F

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RAD54L2	LCE1F
Description		RAD54 like 2	late cornified envelope 1F
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Body
	Molecular Function	Nucleotide Binding DNA Binding Transcription Coregulator Activity Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity ATP-dependent Chromatin Remodeler Activity	Protein Binding Identical Protein Binding
	Biological Process	Chromatin Organization Chromatin Remodeling Positive Regulation Of Transcription By RNA Polymerase II	Epidermis Development Keratinization
Pathways			Formation of the cornified envelope
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163)	Asthma ( 31619474)
Interacting Genes		44 interacting genes: AR ATN1 ATXN1 ATXN1L BANP BHLHE40 CBX3 CRK FAM118B FXR2 HMG20A HNRNPCL1 HOMER1 IMPDH1 KIFC3 KRTAP6-3 LCE1D LCE1F NR3C1 NR5A1 NR5A2 PAICS PIAS1 POU1F1 PPARG PSMA3 RAD51 RBPMS RUNX1T1 RXRA SIAH1 SQSTM1 SUMO1 SUMO2 SUMO3 TAX1BP1 TFAP2D THAP1 TRAF2 TRAF4 UBE2I VCX ZBTB26 ZC2HC1A	90 interacting genes: ADAMTSL4 ALPP CATSPER1 CHIC2 CHRD CRCT1 CREB5 CYP21A2 CYSRT1 FBLN1 HOXA1 IL34 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE2A LCE2B LCE2C LCE2D LCE3B LCE3C LCE4A LCE5A MACO1 MDFI NBPF19 NECTIN2 NOTCH2NLA NTAQ1 NUFIP2 OIT3 OTX1 PCSK5 PLA2G10 POU4F2 PSMB1 RAD54L2 RGS17 RGS20 RNF4 SLC39A7 SMCP SPRY1 SPRY2 SPRY3 TGFB1 TRIM42 UBE2I VASN VWC2 WFDC3
Entrez ID		23132	353137
HPRD ID		10018	13970
Ensembl ID		ENSG00000164080	ENSG00000240386
Uniprot IDs		B3KV54 Q9Y4B4	Q5T754
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Enzyme Binding PML Body Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Transcription Coregulator Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Receptor Activity Nucleus Postsynaptic Cytosol Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Nucleobase-containing Compound Biosynthetic Process Protein Sumoylation Nucleoplasm Negative Regulation Of Macromolecule Biosynthetic Process Transcription By RNA Polymerase II 'de Novo' XMP Biosynthetic Process Presynaptic Cytosol Ubiquitin Protein Ligase Binding Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Intracellular Receptor Signaling Pathway Signaling Adaptor Activity Hormone-mediated Signaling Pathway Chromatin Regulation Of Primary Metabolic Process Chromatin Binding GMP Biosynthetic Process IMP Dehydrogenase Activity DNA-binding Transcription Factor Activity Negative Regulation Of Metabolic Process Protein Tag Activity Purine Ribonucleoside Monophosphate Biosynthetic Process Zinc Ion Binding Regulation Of Gene Expression SUMO Transferase Activity Sequence-specific DNA Binding Double-stranded DNA Binding RNA Polymerase II Transcription Regulator Complex Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Metabolic Process	Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Hair Cycle Protein Binding Identical Protein Binding Branch Elongation Of An Epithelium Axis Elongation Cytosol Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Lens Fiber Cell Differentiation Negative Regulation Of Ras Protein Signal Transduction Microtubule End Negative Regulation Of Cellular Response To Growth Factor Stimulus Bud Elongation Involved In Lung Branching Interstitial Matrix
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