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SYNJ1 and SH3GL1
Number of citations of the paper that reports this interaction (PubMedID
9238017
)
36
Data Source:
HPRD
(in vivo, two hybrid, in vitro)
SYNJ1
SH3GL1
Description
synaptojanin 1
SH3 domain containing GRB2 like 1, endophilin A2
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Microtubule
Vesicle Membrane
Membrane
Membrane Coat
Clathrin Coat Of Coated Pit
Terminal Bouton
Perinuclear Region Of Cytoplasm
Synaptic Membrane
Presynapse
Podosome
Cytoplasm
Endosome
Cytosol
Membrane
Early Endosome Membrane
Cell Projection
Anchoring Junction
Presynapse
Glutamatergic Synapse
Molecular Function
Nucleic Acid Binding
RNA Binding
Phosphatidylinositol-3-phosphate Phosphatase Activity
Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity
Protein Binding
Hydrolase Activity
Phosphatase Activity
Phosphatidylinositol Phosphate 5-phosphatase Activity
Phosphatidylinositol Phosphate 4-phosphatase Activity
Phosphatidylinositol-4-phosphate Phosphatase Activity
Phosphatidylinositol-3,5-bisphosphate 5-phosphatase Activity
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase Activity
Inositol-1,4,5-trisphosphate 5-phosphatase Activity
Protein Binding
Lipid Binding
Identical Protein Binding
Cadherin Binding
Biological Process
Lipid Metabolic Process
Phosphatidylinositol Biosynthetic Process
Neurotransmitter Transport
Endocytosis
Learning
Synaptic Vesicle Priming
Synaptic Vesicle Uncoating
Phosphatidylinositol-3-phosphate Biosynthetic Process
Inositol Phosphate Metabolic Process
Phosphatidylinositol Metabolic Process
Phosphatidylinositol Dephosphorylation
Synaptic Vesicle Endocytosis
Synaptic Vesicle Transport
Membrane Organization
Positive Regulation Of Endosome Organization
Endocytosis
Signal Transduction
Central Nervous System Development
Pathways
Synthesis of PIPs at the plasma membrane
Synthesis of IP2, IP, and Ins in the cytosol
Synthesis of IP3 and IP4 in the cytosol
Clathrin-mediated endocytosis
EGFR downregulation
Negative regulation of MET activity
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
InlB-mediated entry of Listeria monocytogenes into host cell
Drugs
Diseases
GWAS
Platelet reactivity in response to clopidogrel treatment (
32472697
)
Appendicular lean mass (
33097823
)
Hematocrit (
32888494
)
Red cell distribution width (
32888494
)
Interacting Genes
30 interacting genes:
AMPH
AP2A1
AP2M1
BIN1
CDK5
CLTA
CLTC
EPHB2
EPS15
FNBP4
FOXRED1
GRB2
ITSN1
LRRK2
PACSIN1
PACSIN2
PACSIN3
PAX6
PPP3CA
RASAL2
SH3BP1
SH3D19
SH3GL1
SH3GL2
SH3GL3
SH3GLB1
SH3KBP1
SH3YL1
SORBS1
SORBS2
35 interacting genes:
ARHGAP1
ARHGAP8
AXIN1
B3GAT1
CCDC50
CMTM5
CREBBP
DNM1
DNM1L
DPPA4
DPYSL4
EEIG1
FBXO32
GPKOW
ITCH
ITSN2
MAL2
MTA1
NUTM2F
PDCD6IP
PML
PRB3
PSMB1
PTPRO
RHEX
SCAMP5
SEPTIN8
SH2D4A
SH3D19
SH3GL3
SOCS1
SPG21
SYNJ1
VPS37C
YWHAZ
Entrez ID
8867
6455
HPRD ID
09182
03462
Ensembl ID
ENSG00000159082
ENSG00000141985
Uniprot IDs
A0A0D9SGJ6
B9EGN3
C9JFZ1
J3KQV8
O43426
Q05CZ1
Q6FGM0
Q99961
PDB IDs
1W80
2DNR
2VJ0
7A0V
Enriched GO Terms of Interacting Partners
?
Endocytosis
Import Into Cell
Vesicle-mediated Transport
Synaptic Vesicle Endocytosis
Presynaptic Endocytosis
Vesicle-mediated Transport In Synapse
Regulation Of Endocytosis
Glutamatergic Synapse
Endosome
Regulation Of Vesicle-mediated Transport
Postsynaptic Endocytic Zone
Clathrin-dependent Endocytosis
Clathrin-coated Pit
Lipid Binding
Establishment Of Localization In Cell
Regulation Of Cellular Component Organization
Receptor-mediated Endocytosis
Cytosol
Endolysosome Membrane
Cytoskeleton Organization
Clathrin-coated Endocytic Vesicle
Receptor Internalization
Clathrin Coat Of Trans-Golgi Network Vesicle
Clathrin Coat Of Coated Pit
Plasma Membrane
Postsynaptic Neurotransmitter Receptor Internalization
Synapse
Positive Regulation Of Endocytosis
Cell Projection Morphogenesis
Negative Regulation Of Transport
Intracellular Protein Localization
Cellular Localization
AP-2 Adaptor Complex
Regulation Of Transport
Cytoplasmic Vesicle
Membrane Organization
Plasma Membrane Tubulation
Regulation Of Protein Localization To Plasma Membrane
Phospholipid Binding
Intracellular Transport
Intracellular Protein Transport
Synaptic Vesicle
Identical Protein Binding
Clathrin Coat Assembly
Cell Projection
Negative Regulation Of Endocytosis
Clathrin-coated Endocytic Vesicle Membrane
Neuron Projection Morphogenesis
Cytoskeletal Protein Binding
Regulation Of Protein Localization To Cell Periphery
Negative Regulation Of Endocytic Recycling
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Cytoplasm
Membrane Fission
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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