NR1I2 and RXRA

  • Number of citations of the paper that reports this interaction (PMID 9489701)
  • 207
  • Data Source:
  • HPRD (in vitro, two hybrid)

NR1I2

RXRA

Gene Name nuclear receptor subfamily 1, group I, member 2 retinoid X receptor, alpha
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin) ( 23648065)
  • Central corneal thickness ( 22814818 23493294)
  • Corneal structure ( 23291589)
  • Crohn's disease (need for surgery) ( 23665963)
  • Intelligence ( 22449649)
Protein-Protein Interactions 27 interactors: ACTN2 ATP6AP1 CHMP1A DYRK2 EIF3I FGR MAPK7 NCOA1 NCOA2 NCOA3 NCOA6 NCOR2 NFATC4 NUCB2 POU1F1 PPARGC1A PSMC5 RBCK1 RPS6KB1 RXRA RXRB RXRG SDF4 SRC TADA3 TFAP2C UBR5 113 interactors: ACVR1 ACVR1B ALOX15B ARID5A ARNTL BCL3 BRD8 CASP2 CHD9 CLOCK CNOT1 COPS2 CSNK2B CTCF CTNNB1 CTSL DNTTIP2 EDF1 ESR1 ESR2 FUS GADD45A GADD45G GATA2 GK GRIP1 GSK3B HDAC3 HDAC4 HMGA1 IGFBP3 ITGB3BP JAZF1 JMJD1C KIF1A MAPK1 MAPK3 MAPK7 MECR MED1 MED24 MED25 MPG MYOD1 NCOA1 NCOA2 NCOA3 NCOA4 NCOA6 NCOR1 NCOR2 NFKB1 NFKBIB NPAS2 NR0B2 NR1H2 NR1H3 NR1H4 NR1I2 NR1I3 NR2E3 NR2F1 NR2F6 NR3C2 NR4A2 NRBF2 NRIP1 NSD1 PARP1 PLK1 PML POU2F1 POU2F2 PPARA PPARD PPARG PPARGC1A PRKD2 PRMT2 PSMC3IP PSMC5 RAD54L2 RARA RARB RARG RELA RNF8 ROBO4 RPS6KA6 SMAD2 SMARCD3 SMN1 SNW1 SP1 SRC SRF STAT1 TADA3 TAF11 TAF1B TBP TDG THRA THRB TK1 TMPRSS3 TRIM24 TRIP10 TRIP4 UBQLN4 VDR ZBTB16 ZNHIT3
Entrez ID 8856 6256
HPRD ID 04346 01577
Ensembl ID ENSG00000144852
Uniprot IDs F1D8P9 O75469 F1D8Q5 P19793 Q6P3U7
PDB IDs 1ILG 1ILH 1M13 1NRL 1SKX 2O9I 2QNV 3CTB 3HVL 3R8D 4J5W 4J5X 1BY4 1DSZ 1FBY 1FM6 1FM9 1G1U 1G5Y 1K74 1LBD 1MV9 1MVC 1MZN 1R0N 1RDT 1RXR 1XLS 1XV9 1XVP 1YNW 2ACL 2NLL 2P1T 2P1U 2P1V 2ZXZ 2ZY0 3DZU 3DZY 3E00 3E94 3FAL 3FC6 3FUG 3H0A 3KWY 3NSP 3NSQ 3OAP 3OZJ 3PCU 3R29 3R2A 3R5M 3UVV 4J5W 4J5X
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1h  androstane  benzo  bms  car  carboxylate  chlorophenyl  cotreated  cyp3a4  dihydropyridin  hphs  huh7  hydroxypropyl  idazol  imidazol  morpholino  noncanonical  nonclassical  noteworthy  nr1i3  piperazine  piperidin  pregnane  prototypical  pxr  pyrazol  pyridin  translocate  yl 
17q  22cm  canine  centromeric  cfa9  correspond  cosmid  cryba1  distal  dog  grp78  hsa17  hsa17q  hsa9q  hsa9q34  hspa5  lies  linkage  loci  map  mmu2  nf1  occupy  painting  places  probable  syntenic  telomeric  thirds 
Tagcloud (Difference) ?
1h  androstane  benzo  bms  car  carboxylate  chlorophenyl  cotreated  cyp3a4  dihydropyridin  hphs  huh7  hydroxypropyl  idazol  imidazol  morpholino  noncanonical  nonclassical  noteworthy  nr1i3  piperazine  piperidin  pregnane  prototypical  pxr  pyrazol  pyridin  translocate  yl 
17q  22cm  canine  centromeric  cfa9  correspond  cosmid  cryba1  distal  dog  grp78  hsa17  hsa17q  hsa9q  hsa9q34  hspa5  lies  linkage  loci  map  mmu2  nf1  occupy  painting  places  probable  syntenic  telomeric  thirds 
Tagcloud (Intersection) ?