NR1I2 and CHMP1A

Number of citations of the paper that reports this interaction (PubMedID 15604093)
0

Data Source:
BioGRID (two hybrid)

		NR1I2	CHMP1A
Description		nuclear receptor subfamily 1 group I member 2	charged multivesicular body protein 1A
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Nuclear Body Intermediate Filament Cytoskeleton	Autophagosome Membrane Kinetochore Condensed Nuclear Chromosome ESCRT III Complex Nucleus Nuclear Pore Cytoplasm Lysosomal Membrane Endosome Early Endosome Multivesicular Body Microtubule Organizing Center Kinetochore Microtubule Cytosol Plasma Membrane Endosome Membrane Endomembrane System Membrane Nuclear Matrix Midbody Multivesicular Body Membrane Extracellular Exosome Amphisome Membrane
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Nuclear Receptor Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Metallopeptidase Activity Zinc Ion Binding Protein Domain Specific Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Xenobiotic Metabolic Process Signal Transduction Steroid Metabolic Process Positive Regulation Of Gene Expression Cell Differentiation Intracellular Receptor Signaling Pathway Xenobiotic Catabolic Process Xenobiotic Transport Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Intestinal Epithelial Structure Maintenance Cellular Response To Molecule Of Bacterial Origin	Plasma Membrane Repair Autophagy Nucleus Organization Vacuolar Transport Mitotic Chromosome Condensation Mitotic Metaphase Chromosome Alignment Negative Regulation Of Gene Expression Regulation Of Centrosome Duplication Protein Transport Vesicle-mediated Transport Nuclear Membrane Reassembly Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Late Endosome To Vacuole Transport Viral Budding From Plasma Membrane Cell Division Vesicle Fusion With Vacuole Multivesicular Body-lysosome Fusion Midbody Abscission Multivesicular Body Sorting Pathway Membrane Fission Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Late Endosome To Lysosome Transport ESCRT III Complex Disassembly
Pathways			HCMV Late Events
Drugs		Vitamin E Oxiconazole Phenytoin Diethylstilbestrol Clotrimazole Pentobarbital Spironolactone Lindane Flutamide Ritonavir Erlotinib Cyclophosphamide Mephenytoin Carbamazepine Tamoxifen Warfarin Ethotoin Estradiol Mifepristone Methylphenobarbital Ethinylestradiol Ketoconazole Fenofibrate Rifampicin Clonazepam Miconazole Nifedipine Econazole Sulfinpyrazone Phenobarbital Ifosfamide Rifaximin Paclitaxel Dexamethasone Docetaxel Bezafibrate Genistein Prasterone Hyperforin Resveratrol Pregnenolone Quercetin SR12813 Afimoxifene Phenolphthalein Permethrin Dovitinib Chenodeoxycholic acid TO-901317 Hexestrol Triclosan Rilpivirine Pyrethrum extract Myrrh Piperine Troleandomycin Fenofibric acid Estradiol acetate Estradiol benzoate Estradiol cypionate Estradiol dienanthate Estradiol valerate alpha-Tocopherol succinate D-alpha-Tocopherol acetate Dexamethasone acetate
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Hippocampal volume in Alzheimer's disease dementia ( 29274321) LDL cholesterol levels ( 32203549) Lymphocyte percentage of white cells ( 32888494) Total cholesterol levels ( 30275531)	Basal cell carcinoma ( 33549134) Brain morphology (MOSTest) ( 32665545) Diastolic blood pressure ( 30578418) Estimated glomerular filtration rate ( 31152163) Hemoglobin levels ( 32327693) Low tan response ( 29739929) Mean reticulocyte volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Medication use (diuretics) ( 31015401) Plasma homocysteine levels ( 30339177) Red vs. brown/black hair color ( 30531825)
Interacting Genes		34 interacting genes: ACTN2 ATP6AP1 CHMP1A DNMT3L DYRK2 EP300 FGR HNF4A MAPK7 MDM2 NCOA1 NCOA2 NCOA3 NCOA6 NCOR2 NFATC4 NR0B2 NR5A2 NUCB2 POU1F1 PPARGC1A PSMC5 RBCK1 RPS6KB1 RXRA RXRB RXRG SDF4 SRC TADA3 TFAP2C UBE2I UBR5 YAP1	18 interacting genes: C14orf119 CHMP1B DDIT4L GORASP2 LNPK MITD1 NR1I2 PSMA1 SDCBP STAMBP TXN2 UBE2I USP8 VPS4A VPS4B VTA1 YES1 ZDHHC17
Entrez ID		8856	5119
HPRD ID		04346	01237
Ensembl ID		ENSG00000144852	ENSG00000131165
Uniprot IDs		F1D8P9 O75469	A0A6Q8PFX8 Q9HD42
PDB IDs		1ILG 1ILH 1M13 1NRL 1SKX 2O9I 2QNV 3CTB 3HVL 3R8D 4J5W 4J5X 4NY9 4S0S 4S0T 4X1F 4X1G 4XAO 4XHD 5A86 5X0R 6BNS 6DUP 6HJ2 6HTY 6NX1 6P2B 6S41 6TFI 6XP9 7AX8 7AX9 7AXA 7AXB 7AXC 7AXD 7AXE 7AXF 7AXG 7AXH 7AXI 7AXJ 7AXK 7AXL 7N2A 7RIO 7RIU 7RIV 7YFK 8CCT 8CF9 8CH8 8E3N 8EQZ 8F5Y 8FPE 8SVN 8SVO 8SVP 8SVQ 8SVR 8SVS 8SVT 8SVU 8SVX 8SZV 9BEQ 9FZG 9FZH 9FZI 9FZJ	2JQ9 2YMB 4A5X
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Nuclear Receptor Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Gene Expression Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Receptor-mediated Signaling Pathway Intracellular Receptor Signaling Pathway Positive Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Hormone-mediated Signaling Pathway Regulation Of Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Intracellular Signal Transduction Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Transcription Coactivator Activity Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Retinoic Acid Receptor Signaling Pathway Negative Regulation Of RNA Metabolic Process Nucleoplasm Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Negative Regulation Of Transcription By RNA Polymerase II Rhythmic Process Nuclear Retinoid X Receptor Binding Cellular Developmental Process Nuclear Receptor Activity Transcription By RNA Polymerase II Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Developmental Process Negative Regulation Of Macromolecule Biosynthetic Process Signal Transduction RNA Polymerase II Transcription Regulator Complex Positive Regulation Of Gene Expression Retinoic Acid-responsive Element Binding Nuclear Protein Quality Control By The Ubiquitin-proteasome System	ESCRT III Complex Disassembly ESCRT Complex Disassembly Multivesicular Body Sorting Pathway Viral Budding Via Host ESCRT Complex Midbody Abscission Nuclear Membrane Reassembly Viral Budding Mitotic Cytokinetic Process Endosome Organization Multivesicular Body Assembly Multivesicular Body Organization Late Endosome To Vacuole Transport Cytokinetic Process Endosome Transport Via Multivesicular Body Sorting Pathway Nuclear Membrane Organization Viral Budding From Plasma Membrane Membrane Assembly Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Midbody Late Endosome To Lysosome Transport Late Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Late Endosomal Microautophagy Nuclear Pore Cytoskeleton-dependent Cytokinesis Viral Release From Host Cell Plasma Membrane Repair Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Endosome Endosome Membrane Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Vesicle Organization Membrane Fission Protein-containing Complex Disassembly Viral Process Mitotic Metaphase Chromosome Alignment Late Endosome Membrane Autophagosome Maturation Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Vacuolar Transport Metaphase Chromosome Alignment Mitotic Cytokinesis Mitotic Nuclear Membrane Reassembly ATPase Complex Chromosome Localization Cell Division Extracellular Exosome Positive Regulation Of Exocytosis Nucleus Organization Proteolysis
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