SCEL and MYCBP2

		SCEL	MYCBP2
Description		sciellin	MYC binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytoplasm Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Microtubule Cytoskeleton Membrane Axon Cell Projection
	Molecular Function	Protein Binding Metal Ion Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Transferase Activity Small GTPase Binding Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Epidermis Development Response To Mechanical Stimulus Embryo Development Ending In Birth Or Egg Hatching Keratinocyte Differentiation Positive Regulation Of Canonical Wnt Signaling Pathway	Axon Guidance Motor Neuron Axon Guidance Regulation Of Synaptic Assembly At Neuromuscular Junction Protein Ubiquitination Branchiomotor Neuron Axon Guidance Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Protein Ubiquitination Regulation Of Protein Localization Circadian Regulation Of Gene Expression Negative Regulation Of Protein Catabolic Process Rhythmic Process Cell Morphogenesis Involved In Neuron Differentiation Neuromuscular Process Regulation Of Cytoskeleton Organization Axon Development Protein K48-linked Ubiquitination Regulation Of Axon Guidance
Pathways
Drugs
Diseases
GWAS		Chronotype ( 30696823) Craniofacial microsomia ( 26853712) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Morning person ( 30696823)	Chronotype ( 30696823) Iris heterochromicity ( 30895295) Morning person ( 30696823) Preeclampsia ( 23551011) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		13 interacting genes: APP DAPK1 FXR2 GOLGA2 KIFC3 LRRK1 LRRK2 MTUS2 NMI PTPRD TSC22D2 TSGA10 TXNIP	50 interacting genes: AATF APPL1 ARL6IP5 ASB8 ATP13A2 BTG3 CALM1 CD81 CEBPA CFL1 CUEDC2 DHRS4L2 DSCR9 DYRK1A ERBB3 FHL3 FSCN1 HSP90AB1 HUNK IGFBP6 LCOR LDHB LSM14A MYC NDUFB9 NMNAT2 OAZ1 PABPN1 PI4KB PRXL2A PTPN12 PUF60 RGPD8 RPS5 RSPH1 SERPINB6 SOD1 SPARCL1 SPRYD3 SRPK2 TBC1D9 TBC1D9B TBR1 TTN UBE2D2 UBE2D3 UBE2L3 UCHL1 YWHAG YWHAQ
Entrez ID		8796	23077
HPRD ID		09161	10104
Ensembl ID		ENSG00000136155	ENSG00000005810
Uniprot IDs		O95171	O75592
PDB IDs			5O6C 6T7F
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Golgi-associated Vesicle Regulation Of Synapse Organization Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Cellular Response To Catecholamine Stimulus Cellular Response To Manganese Ion Response To Catecholamine Response To Manganese Ion Cytoskeleton Syntaxin-1 Binding Golgi Organization Microtubule Binding Positive Regulation Of Protein Ubiquitination Neuron Projection Positive Regulation Of Post-translational Protein Modification Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Postsynapse Organization Positive Regulation Of Protein Modification Process Regulation Of Synapse Assembly Positive Regulation Of Inflammatory Response Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Metabolic Process Modulation Of Chemical Synaptic Transmission Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Dendritic Spine Morphogenesis Regulation Of Protein Ubiquitination Amyloid-beta Complex Growth Cone Lamellipodium Postsynapse Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of CAMP/PKA Signal Transduction Cytoplasm Modulation Of Excitatory Postsynaptic Potential DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly Positive Regulation Of Catabolic Process Positive Regulation Of Programmed Cell Death Regulation Of Post-translational Protein Modification Regulation Of Neuronal Synaptic Plasticity Regulation Of Canonical Wnt Signaling Pathway Microtubule Cytoskeleton Regulation Of Cell Junction Assembly Myeloid Cell Development	Cytoplasm Intracellular Signal Transduction
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