SCEL and KIFC3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SCEL	KIFC3
Description		sciellin	kinesin family member C3
Image		No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytoplasm Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Cytoplasm Mitochondrion Golgi Apparatus Centrosome Cytoskeleton Kinesin Complex Microtubule Adherens Junction Zonula Adherens Microtubule Cytoskeleton Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Extracellular Exosome Anchoring Junction
	Molecular Function	Protein Binding Metal Ion Binding	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Identical Protein Binding
	Biological Process	Epidermis Development Response To Mechanical Stimulus Embryo Development Ending In Birth Or Egg Hatching Keratinocyte Differentiation Positive Regulation Of Canonical Wnt Signaling Pathway	Microtubule-based Process Microtubule-based Movement Golgi Organization Visual Perception Zonula Adherens Maintenance Epithelial Cell-cell Adhesion
Pathways
Drugs
Diseases
GWAS		Chronotype ( 30696823) Craniofacial microsomia ( 26853712) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Morning person ( 30696823)
Interacting Genes		13 interacting genes: APP DAPK1 FXR2 GOLGA2 KIFC3 LRRK1 LRRK2 MTUS2 NMI PTPRD TSC22D2 TSGA10 TXNIP	213 interacting genes: ABI2 ABI3 AIRIM ANKRD23 ANXA13 APP APPL2 ARNT2 ATF2 AXIN2 BARD1 BCL6 BEGAIN BFSP1 BYSL CARD9 CATSPERT CBFA2T2 CBX8 CBY2 CCDC102B CCDC136 CCDC146 CCDC187 CCDC198 CCDC28A CCDC33 CCHCR1 CCND3 CDC37 CDK18 CDKN1A CDR2 CEP55 CEP57L1 CLIP4 COG3 COG7 CREB5 CWF19L2 CYTH4 DCTN2 DCX DEUP1 DISC1 DSCAM DTNBP1 EIF3D ENKD1 ESRRG EXOC5 EXOC7 EXOC8 FAM124A FAM161A FAM90A1 FANCL FBXO7 FCHSD2 FEM1A FLYWCH1 FOSL1 GADD45GIP1 GEM GIGYF1 GMCL1 GOLGA1 GOLGA2 GORASP2 HAUS1 HMG20A HOMEZ HSBP1 HSF2BP ICA1L IGFN1 IHO1 IKZF3 IL16 IQUB ITGB3BP KANK2 KANSL1 KDM1A KIAA0753 KRT14 KRT15 KRT16 KRT18 KRT19 KRT26 KRT3 KRT31 KRT32 KRT35 KRT38 KRT4 KRT40 KRT5 KRT6A KRT6B KRT6C KRT75 KRT76 KRT8 KRTAP19-5 KRTAP19-6 LBX1 LENG1 LIN37 LNX1 LZTS1 LZTS2 MBD3L1 MCC MCM7 MED4 MFAP1 MID2 MKRN3 MOS MRFAP1 MTUS2 MYO15B NAB2 NDC80 NDEL1 NEBL NECAB2 NEDD4 NEDD4L NEFL NSMF NUP62 PFDN6 PHC2 PIAS2 PIBF1 PIN1 PNMA5 PPP1R13B PRDM6 PRKAA2 PRPF18 PRPF31 PRPH PSMB1 RABIF RAD51D RAD54L2 RBM41 RSPH14 RUNX1T1 SCEL SCNM1 SCOC SHISA6 SIAH1 SMARCE1 SNAP29 SORBS3 SOX30 SOX5 SPATA2 SPATC1L SSX2IP STMN3 STX11 STX1A SVIL SYCE1 SYCE2 SYT6 SYTL4 TASOR2 TBC1D22B TCEANC TFIP11 TLE5 TNIP1 TNNI1 TPM3 TRAF2 TRIM14 TRIM23 TRIM27 TRIM41 TRIM54 TSG101 TSGA10IP TSR2 UBC USH1G USP2 VIM VPS52 WASF3 ZBED1 ZBTB16 ZBTB8A ZGPAT ZNF180 ZNF20 ZNF250 ZNF417 ZNF446 ZNF572 ZNF655 ZNF688 ZNF774 ZNF785 ZNF835 ZRANB1
Entrez ID		8796	3801
HPRD ID		09161	05171
Ensembl ID		ENSG00000136155	ENSG00000140859
Uniprot IDs		O95171	B7Z5U4 B7Z808 B7Z896 F5H3M2 H3BMZ5 Q9BVG8
PDB IDs			5WDE
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Golgi-associated Vesicle Regulation Of Synapse Organization Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Cellular Response To Catecholamine Stimulus Cellular Response To Manganese Ion Response To Catecholamine Response To Manganese Ion Cytoskeleton Syntaxin-1 Binding Golgi Organization Microtubule Binding Positive Regulation Of Protein Ubiquitination Neuron Projection Positive Regulation Of Post-translational Protein Modification Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Postsynapse Organization Positive Regulation Of Protein Modification Process Regulation Of Synapse Assembly Positive Regulation Of Inflammatory Response Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Metabolic Process Modulation Of Chemical Synaptic Transmission Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Dendritic Spine Morphogenesis Regulation Of Protein Ubiquitination Amyloid-beta Complex Growth Cone Lamellipodium Postsynapse Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of CAMP/PKA Signal Transduction Cytoplasm Modulation Of Excitatory Postsynaptic Potential DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly Positive Regulation Of Catabolic Process Positive Regulation Of Programmed Cell Death Regulation Of Post-translational Protein Modification Regulation Of Neuronal Synaptic Plasticity Regulation Of Canonical Wnt Signaling Pathway Microtubule Cytoskeleton Regulation Of Cell Junction Assembly Myeloid Cell Development	Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Intermediate Filament Structural Constituent Of Skin Epidermis Keratin Filament Protein Binding Cytoskeleton Organization Supramolecular Fiber Organization Organelle Organization Cytoskeleton Structural Constituent Of Cytoskeleton Identical Protein Binding Structural Molecule Activity Nucleus Keratinization Centrosome Organelle Localization Microtubule-based Process Microtubule Organizing Center Epithelial Cell Differentiation Positive Regulation Of Actin Nucleation Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cell Differentiation Hepatocyte Apoptotic Process Microtubule Cytoskeleton Organization Flemming Body Cytosol Regulation Of Transcription By RNA Polymerase II Chromosome Localization Epidermis Development Metaphase Chromosome Alignment Cellular Developmental Process Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Zinc Ion Binding Regulation Of Neuron Projection Development Post-translational Protein Modification Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Ubiquitin Protein Ligase Activity Intermediate Filament Polymerization Or Depolymerization Vesicle Tethering Involved In Exocytosis Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Neurofilament Cytoskeleton Organization Scaffold Protein Binding Negative Regulation Of DNA-templated Transcription Developmental Process Epithelial Cell Apoptotic Process
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