SCEL and TSGA10

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid)

		SCEL	TSGA10
Name		sciellin	testis specific 10
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytoplasm Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Cytoplasm Centriole Cytoskeleton Motile Cilium Sperm Fibrous Sheath Neuron Projection Sperm Principal Piece
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Epidermis Development Response To Mechanical Stimulus Embryo Development Ending In Birth Or Egg Hatching Keratinocyte Differentiation Positive Regulation Of Canonical Wnt Signaling Pathway	Spermatogenesis Cell Projection Assembly
GWAS		Chronotype ( 30696823 ) Craniofacial microsomia ( 26853712 ) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189 ) Morning person ( 30696823 )	Bipolar disorder ( 21926972 ) High light scatter reticulocyte count ( 32888494 ) High light scatter reticulocyte percentage of red cells ( 32888494 ) Intelligence (MTAG) ( 29326435 ) Reticulocyte count ( 32888494 ) Reticulocyte fraction of red cells ( 32888494 )
Interacting Genes		13 interacting genes: APP DAPK1 FXR2 GOLGA2 KIFC3 LRRK1 LRRK2 MTUS2 NMI PTPRD TSC22D2 TSGA10 TXNIP	81 interacting genes: AARD AXIN1 AXIN2 BCL6B BIRC2 CBX8 CBY2 CCDC136 CCDC33 CCDC88B CCHCR1 CDC73 CDK18 CDSN CEP44 CEP57 CEP57L1 COG6 CREB5 DISC1 FAM161A FAM161B FBF1 GCC2-AS1 GOLGA2 HDAC4 HDX HIF1A HNRNPM HOOK2 JRK KANK2 KIAA1328 KRT6A KRT76 LMNA LZTS1 MAD1L1 MATR3 MBD3L1 MID2 NAB2 PAK5 PIBF1 PKN1 PLEKHA7 PPHLN1 PPP1R13B PPP1R18 PRDM14 PRDM6 PRPF31 RBAK RCOR3 RNF6 RTP5 SCEL SORBS3 SYT6 TCEA2 TLE5 TP53BP2 TRIM14 TRIM29 ZBTB24 ZBTB26 ZBTB38 ZBTB39 ZNF124 ZNF2 ZNF205 ZNF23 ZNF410 ZNF417 ZNF426 ZNF438 ZNF490 ZNF544 ZNF587 ZNF599 ZNF670
Entrez ID		8796	80705
HPRD ID		09161	06202
Ensembl ID		ENSG00000136155	ENSG00000135951
Uniprot IDs		O95171	A0A218MIY9 Q9BZW7
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Identical Protein Binding Golgi-associated Vesicle Regulation Of Synapse Organization Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Cellular Response To Catecholamine Stimulus Cellular Response To Manganese Ion Response To Catecholamine Response To Manganese Ion Cytoskeleton Syntaxin-1 Binding Golgi Organization Microtubule Binding Positive Regulation Of Protein Ubiquitination Neuron Projection Positive Regulation Of Post-translational Protein Modification Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Postsynapse Organization Positive Regulation Of Protein Modification Process Regulation Of Synapse Assembly Positive Regulation Of Inflammatory Response Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Metabolic Process Modulation Of Chemical Synaptic Transmission Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Dendritic Spine Morphogenesis Regulation Of Protein Ubiquitination Amyloid-beta Complex Growth Cone Lamellipodium Postsynapse Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of CAMP/PKA Signal Transduction Cytoplasm Modulation Of Excitatory Postsynaptic Potential DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly Positive Regulation Of Catabolic Process Positive Regulation Of Programmed Cell Death Regulation Of Post-translational Protein Modification Regulation Of Neuronal Synaptic Plasticity Regulation Of Canonical Wnt Signaling Pathway Microtubule Cytoskeleton Regulation Of Cell Junction Assembly Myeloid Cell Development	Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Zinc Ion Binding Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Nucleus Regulation Of Primary Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Identical Protein Binding Negative Regulation Of Macromolecule Biosynthetic Process DNA Binding Negative Regulation Of Biosynthetic Process Centrosome Negative Regulation Of Metabolic Process P53 Binding Negative Regulation Of Macromolecule Metabolic Process Microtubule Binding Metal Ion Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Wnt Signaling Pathway