SNAP23 and SNAPIN

Number of citations of the paper that reports this interaction (PMID 12877659)
25

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		SNAP23	SNAPIN
Gene Name		synaptosomal-associated protein, 23kDa	SNAP-associated protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Plasma Membrane Focal Adhesion SNARE Complex Specific Granule Azurophil Granule Mast Cell Granule Neuron Projection Synapse Extracellular Vesicular Exosome	Golgi Membrane Nucleolus Golgi Apparatus Synaptic Vesicle Cell Junction Transport Vesicle Secretory Granule Cytoplasmic Vesicle Membrane Synaptic Vesicle Membrane BLOC-1 Complex Synapse Perinuclear Region Of Cytoplasm
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	SNARE Binding Protein Binding
	Biological Process	Histamine Secretion By Mast Cell Post-Golgi Vesicle-mediated Transport Vesicle Targeting Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Membrane Membrane Organization Membrane Fusion	Intracellular Protein Transport Neurotransmitter Secretion Anterograde Axon Cargo Transport Endosome To Lysosome Transport Negative Regulation Of Neuron Projection Development Viral Process Synaptic Vesicle Exocytosis Synaptic Vesicle Maturation Neuron Projection Development Synaptic Vesicle Fusion To Presynaptic Membrane Melanosome Organization Regulation Of Protein Binding Synaptic Vesicle Transport Anterograde Synaptic Vesicle Transport Terminal Button Organization Autophagic Vacuole Maturation Positive Regulation Of Late Endosome To Lysosome Transport
Pathways		Translocation of GLUT4 to the plasma membrane trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding	Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		34 interactors: ABI2 ABI3 CFTR FXR2 ITSN1 KIF5B MATR3 NAPA NAPB PRKCA SCAMP1 SCAMP2 SCGN SNAPIN SNTG1 STX11 STX12 STX1A STX1B STX2 STX3 STX4 STX5 STX6 STXBP2 STXBP5 TLK1 VAMP1 VAMP2 VAMP3 VAMP5 VAMP7 VAMP8 WASH2P	33 interactors: BLOC1S1 BLOC1S2 BLOC1S4 BLOC1S5 BLOC1S6 BNIPL CSNK1D DDR1 DTNBP1 EBAG9 EEF1G GPRASP1 HAP1 IKBKAP IMMT KAT5 KAT7 KIF5C LAMC1 LRP12 MAPK14 MET PRKACA RGS7 RNF13 SHBG SMAD2 SNAP23 SNAP25 SPAG5 SPP1 ST7 TRPV1
Entrez ID		8773	23557
HPRD ID		03962	06111
Ensembl ID		ENSG00000092531	ENSG00000143553
Uniprot IDs		A8K287 O00161	O95295
PDB IDs		1NHL 3ZUS
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle Organization Vesicle-mediated Transport Establishment Of Localization In Cell Exocytosis Cellular Localization Protein Transport Membrane Organization Establishment Of Protein Localization Intracellular Transport Secretion By Cell Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Docking Membrane Docking Secretion Protein Localization Neurotransmitter Secretion Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Regulation Of Neurotransmitter Levels Synaptic Vesicle Exocytosis Neurotransmitter Transport Synaptic Vesicle Transport Golgi Vesicle Transport Transport Establishment Of Vesicle Localization Vesicle Localization Cellular Protein Localization SNARE Complex Assembly Regulation Of Exocytosis Establishment Of Organelle Localization Organelle Organization Regulation Of Cellular Localization Cell-cell Signaling Organelle Localization Synaptic Transmission Regulation Of Secretion Regulation Of Vesicle-mediated Transport Calcium Ion-dependent Exocytosis Positive Regulation Of Synaptic Transmission Regulation Of Synaptic Vesicle Priming Positive Regulation Of Exocytosis Golgi To Plasma Membrane Protein Transport Positive Regulation Of Transport Neutrophil Degranulation Regulation Of Cellular Component Organization Golgi To Plasma Membrane Transport Regulation Of Synaptic Transmission	Anterograde Axon Cargo Transport Anterograde Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Axon Cargo Transport Synaptic Vesicle Transport Establishment Of Vesicle Localization Vesicle Localization Cytoskeleton-dependent Intracellular Transport Cellular Pigmentation Vesicle Organization Establishment Of Organelle Localization Microtubule-based Transport Cell-cell Signaling Movement Of Cell Or Subcellular Component Organelle Localization Synaptic Transmission Microtubule-based Movement Pigmentation Microtubule-based Process Post-Golgi Vesicle-mediated Transport Organelle Organization Vesicle-mediated Transport Platelet Dense Granule Organization Generation Of Neurons Signaling Neurogenesis Neuron Projection Development Cell Communication Cell Projection Organization Cell Development Cell Differentiation Neuron Development Nervous System Development Response To Stimulus Establishment Of Localization In Cell Regulation Of Growth Neuron Differentiation Membrane Organization Transport Secretory Granule Organization Intracellular Transport Peptidyl-amino Acid Modification Golgi Vesicle Transport System Development Cellular Localization Cellular Process Endosome To Melanosome Transport Pigment Granule Maturation Synaptic Vesicle Docking
Tagcloud ?		apical brevin brevins cellubrevin clostridial codistributed cryosections exocytosis exocytotic immunogold insensitive maleimide nem neurotoxin neurotoxins nsf nts proteolyze snare snares syntaxin tent tetanus ti ultrathin vamp vesicle	acidic adaptor altogether bace1 brains cleaving coupling defective deleting disrupting dynein endocytic endosomes enhancing generating happ live lysosomal lysosomes mechanistic organelles overexpressing reduces rescue retrograde secretase traffic transport turnover
Tagcloud (Difference) ?		apical brevin brevins cellubrevin clostridial codistributed cryosections exocytosis exocytotic immunogold insensitive maleimide nem neurotoxin neurotoxins nsf nts proteolyze snare snares syntaxin tent tetanus ti ultrathin vamp vesicle	acidic adaptor altogether bace1 brains cleaving coupling defective deleting disrupting dynein endocytic endosomes enhancing generating happ live lysosomal lysosomes mechanistic organelles overexpressing reduces rescue retrograde secretase traffic transport turnover
Tagcloud (Intersection) ?