SNAP23 and STXBP5

Number of citations of the paper that reports this interaction (PMID 12832401)
26

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		SNAP23	STXBP5
Gene Name		synaptosomal-associated protein, 23kDa	syntaxin binding protein 5 (tomosyn)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Plasma Membrane Focal Adhesion SNARE Complex Specific Granule Azurophil Granule Mast Cell Granule Neuron Projection Synapse Extracellular Vesicular Exosome	Cytoplasm Acetylcholine-gated Channel Complex Synaptic Vesicle Cell Junction Cytoplasmic Vesicle Membrane
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	Syntaxin-1 Binding
	Biological Process	Histamine Secretion By Mast Cell Post-Golgi Vesicle-mediated Transport Vesicle Targeting Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Membrane Membrane Organization Membrane Fusion	Exocytosis Regulation Of Gene Expression Protein Transport Regulation Of Exocytosis Regulation Of Blood Coagulation Positive Regulation Of Exocytosis
Pathways		Translocation of GLUT4 to the plasma membrane trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS			Coagulation factor levels ( 20231535)
Protein-Protein Interactions		34 interactors: ABI2 ABI3 CFTR FXR2 ITSN1 KIF5B MATR3 NAPA NAPB PRKCA SCAMP1 SCAMP2 SCGN SNAPIN SNTG1 STX11 STX12 STX1A STX1B STX2 STX3 STX4 STX5 STX6 STXBP2 STXBP5 TLK1 VAMP1 VAMP2 VAMP3 VAMP5 VAMP7 VAMP8 WASH2P	3 interactors: SNAP23 STX1A STX4
Entrez ID		8773	134957
HPRD ID		03962	06845
Ensembl ID		ENSG00000092531
Uniprot IDs		A8K287 O00161	Q5T5C0
PDB IDs		1NHL 3ZUS
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle Organization Vesicle-mediated Transport Establishment Of Localization In Cell Exocytosis Cellular Localization Protein Transport Membrane Organization Establishment Of Protein Localization Intracellular Transport Secretion By Cell Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Docking Membrane Docking Secretion Protein Localization Neurotransmitter Secretion Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Regulation Of Neurotransmitter Levels Synaptic Vesicle Exocytosis Neurotransmitter Transport Synaptic Vesicle Transport Golgi Vesicle Transport Transport Establishment Of Vesicle Localization Vesicle Localization Cellular Protein Localization SNARE Complex Assembly Regulation Of Exocytosis Establishment Of Organelle Localization Organelle Organization Regulation Of Cellular Localization Cell-cell Signaling Organelle Localization Synaptic Transmission Regulation Of Secretion Regulation Of Vesicle-mediated Transport Calcium Ion-dependent Exocytosis Positive Regulation Of Synaptic Transmission Regulation Of Synaptic Vesicle Priming Positive Regulation Of Exocytosis Golgi To Plasma Membrane Protein Transport Positive Regulation Of Transport Neutrophil Degranulation Regulation Of Cellular Component Organization Golgi To Plasma Membrane Transport Regulation Of Synaptic Transmission	Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Fusion Synaptic Vesicle Exocytosis Organelle Fusion Neurotransmitter Secretion Synaptic Vesicle Transport Membrane Fusion Regulation Of Neurotransmitter Levels Neurotransmitter Transport Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Establishment Of Organelle Localization Exocytosis Organelle Localization Secretion By Cell Synaptic Transmission Positive Regulation Of Exocytosis Secretion Vesicle Docking Post-Golgi Vesicle-mediated Transport Membrane Docking Membrane Organization Cell-cell Signaling Positive Regulation Of Synaptic Transmission Regulation Of Exocytosis Regulation Of Insulin Secretion Protein Transport Vesicle-mediated Transport Positive Regulation Of Eosinophil Degranulation Establishment Of Protein Localization Regulation Of Peptide Hormone Secretion Intracellular Transport Regulation Of Hormone Secretion Golgi Vesicle Transport Regulation Of Synaptic Transmission Protein Localization Positive Regulation Of Secretion Cellular Protein Complex Assembly Establishment Of Localization In Cell Regulation Of Vesicle-mediated Transport Regulation Of Protein Secretion Positive Regulation Of Protein Localization To Cell Surface Positive Regulation Of Immunoglobulin Secretion Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Docking Cellular Localization Synaptic Vesicle Priming SNARE Complex Assembly Histamine Secretion By Mast Cell
Tagcloud ?		apical brevin brevins cellubrevin clostridial codistributed cryosections exocytosis exocytotic immunogold insensitive maleimide nem neurotoxin neurotoxins nsf nts proteolyze snare snares syntaxin tent tetanus ti ultrathin vamp vesicle	al355149 algorithm annotation array cisplatin dataset deregulated deregulation existing fam46a fluorouracil lnc lncrna lncrnas man1a2 mbl2 microdissected ncfans nodal noticed paclitaxel ppp2r4 reannotation reserve scc sprr2d tongue tumorigenic validate
Tagcloud (Difference) ?		apical brevin brevins cellubrevin clostridial codistributed cryosections exocytosis exocytotic immunogold insensitive maleimide nem neurotoxin neurotoxins nsf nts proteolyze snare snares syntaxin tent tetanus ti ultrathin vamp vesicle	al355149 algorithm annotation array cisplatin dataset deregulated deregulation existing fam46a fluorouracil lnc lncrna lncrnas man1a2 mbl2 microdissected ncfans nodal noticed paclitaxel ppp2r4 reannotation reserve scc sprr2d tongue tumorigenic validate
Tagcloud (Intersection) ?