SNAP23

Name	synaptosome associated protein 23
Structure
Novel Interactors	1 novel interactors: SCARB1
Interactors	32 interactors: ABI2 ABI3 CFTR FXR2 ITSN1 KIF5B MATR3 NAPA NAPB PRKCA SCAMP1 SCAMP2 SCGN SNAPIN SNTG1 STX11 STX12 STX1A STX1B STX3 STX4 STX5 STX6 STXBP2 STXBP5 TLK1 VAMP1 VAMP2 VAMP3 VAMP7 VAMP8 WASH2P
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Plasma Membrane Adherens Junction Focal Adhesion Cilium Membrane Phagocytic Vesicle Membrane SNARE Complex Cytoplasmic Vesicle Specific Granule Membrane Specific Granule Azurophil Granule Neuron Projection Synapse Extracellular Exosome Tertiary Granule Membrane Presynapse
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Histamine Secretion By Mast Cell Exocytosis Post-Golgi Vesicle-mediated Transport Vesicle Targeting Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Membrane Fusion
Pathways	ER-Phagosome pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane trans-Golgi Network Vesicle Budding Neutrophil degranulation RHOA GTPase cycle RHOB GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle
GWAS	Bipolar disorder ( 31043756 )
Entrez ID	8773
HPRD ID	03962
Ensembl ID	ENSG00000092531
Uniprot IDs	A8K287 O00161
PDB IDs	1NHL 3ZUS
GO Terms Enriched among Interactors ?	SNARE Complex SNAP Receptor Activity Vesicle Fusion Organelle Membrane Fusion Membrane Fusion Organelle Fusion SNARE Binding Exocytosis Organelle Localization By Membrane Tethering Membrane Docking Vesicle Docking Protein Transport Establishment Of Protein Localization Vesicle-mediated Transport Secretion By Cell Vesicle Organization Secretion Membrane Organization Establishment Of Localization In Cell Intracellular Protein Localization SNARE Complex Assembly Syntaxin Binding Organelle Localization Intracellular Protein Transport Regulation Of Exocytosis Cellular Localization Intracellular Transport Regulation Of Synaptic Vesicle Priming Regulation Of Vesicle-mediated Transport Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Regulation Of Secretion By Cell Regulated Exocytosis Calcium-ion Regulated Exocytosis Endomembrane System Regulation Of Secretion Zymogen Granule Membrane Phagocytic Vesicle Positive Regulation Of Exocytosis Neutrophil Degranulation Regulation Of Histamine Secretion By Mast Cell Vesicle-mediated Transport In Synapse Neuron Projection Recycling Endosome Membrane Secretory Granule Regulation Of Hormone Secretion Golgi Vesicle Transport Positive Regulation Of Secretion By Cell Regulation Of Regulated Secretory Pathway Synaptic Vesicle Exocytosis Synaptic Vesicle Membrane