CBFB and CHGB

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CBFB	CHGB
Gene Name		core-binding factor, beta subunit	chromogranin B (secretogranin 1)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Membrane	Extracellular Region Secretory Granule
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding	Hormone Activity Protein Binding
	Biological Process	Osteoblast Differentiation Transcription From RNA Polymerase II Promoter Lymphocyte Differentiation Myeloid Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Maturation Definitive Hemopoiesis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CBFA2T2 CHGB COPRS CUL5 RAB2A RNF7 RUNX1 RUNX2 RUNX3	31 interactors: ACACA ANXA7 APP ATXN2 CBFB CCDC92 CDKN1A FGFR3 MARK3 MGLL MOGS OGG1 PKN2 POLD1 POLR2E PTEN RAC2 RAP1B RCC1 RXRG S100A8 SAFB2 SGK223 SLC25A6 TAZ TK1 TUBB2A TWF2 UBQLN1 UBTF YLPM1
Entrez ID		865	1114
HPRD ID		00418	07512
Ensembl ID		ENSG00000067955	ENSG00000089199
Uniprot IDs		Q13951	P05060
PDB IDs		1CL3 1E50 1H9D
Enriched GO Terms of Interacting Partners?		Peripheral Nervous System Neuron Development Hair Follicle Morphogenesis Epidermis Morphogenesis Skin Morphogenesis Chondrocyte Differentiation Hair Follicle Development Hair Cycle Process Hair Cycle Peripheral Nervous System Development Skeletal System Development Positive Regulation Of Progesterone Secretion Regulation Of Cell Proliferation Regulation Of Progesterone Secretion Cell Maturation Regulation Of Hair Follicle Cell Proliferation Tissue Development Intrinsic Apoptotic Signaling Pathway Cartilage Development Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Differentiation Transcription From RNA Polymerase II Promoter Skin Development Negative Regulation Of Granulocyte Differentiation Myeloid Progenitor Cell Differentiation Positive Regulation Of Granulocyte Differentiation Connective Tissue Development Epidermis Development Protein Neddylation Organ Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Histone H4-R3 Methylation Osteoblast Fate Commitment Regulation Of Female Gonad Development Regulation Of Cellular Process Epithelium Development Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Response To Redox State Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Hematopoietic Stem Cell Proliferation Apoptotic Signaling Pathway Regulation Of Odontogenesis Of Dentin-containing Tooth System Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Interferon-gamma Production Histone Arginine Methylation Regulation Of RNA Biosynthetic Process	Regulation Of Cellular Component Organization Regulation Of Growth Regulation Of Developmental Growth Cellular Metabolic Process Cellular Component Assembly Regulation Of Mitotic Cell Cycle Regulation Of Metabolic Process Cell Differentiation Regulation Of Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Synaptic Transmission Response To Metal Ion Response To Lipid Regulation Of Gene Expression Cellular Response To Growth Factor Stimulus Regulation Of Cell Development Generation Of Neurons Response To Growth Factor Phosphate-containing Compound Metabolic Process Response To Organic Cyclic Compound Protein Homotetramerization Platelet Activation Positive Regulation Of Metabolic Process Response To Stress Metabolic Process Neurogenesis Response To Organic Substance Positive Regulation Of Lamellipodium Assembly Cellular Process Apoptotic Process Positive Regulation Of Cell Cycle Process Neurotrophin Signaling Pathway Defense Response Hemostasis DNA-templated Transcription, Initiation Negative Regulation Of Developmental Growth Response To Wounding Long Term Synaptic Depression Programmed Cell Death Regulation Of Neurogenesis Nucleotide-excision Repair Positive Regulation Of Lamellipodium Organization Negative Regulation Of Growth Cell Death Death Cell Development Regulation Of Protein Import Into Nucleus, Translocation Developmental Process Regulation Of Cell Morphogenesis Response To Inorganic Substance
Tagcloud ?		abl alfa aml1 amplified apl bcr characterizing clonospecific cml confirmation debate eto igh immunoglobin inv issues leukaemia mow myh1 offers opportunity presently progress purposes quantitate rearrangements residual tcr truly	adjunct aggressiveness atrx avidity cc chga chromogranin classifications cytoplasmic daxx exome fdg germline hippel inherited ki lastly lindau neuroendocrine pnet pnets pten retardation rho subcellular tensin thalassemia vhl von
Tagcloud (Difference) ?		abl alfa aml1 amplified apl bcr characterizing clonospecific cml confirmation debate eto igh immunoglobin inv issues leukaemia mow myh1 offers opportunity presently progress purposes quantitate rearrangements residual tcr truly	adjunct aggressiveness atrx avidity cc chga chromogranin classifications cytoplasmic daxx exome fdg germline hippel inherited ki lastly lindau neuroendocrine pnet pnets pten retardation rho subcellular tensin thalassemia vhl von
Tagcloud (Intersection) ?