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CHGB and CBFB
Number of citations of the paper that reports this interaction (PubMedID
16169070
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
CHGB
CBFB
Description
chromogranin B
core-binding factor subunit beta
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Endoplasmic Reticulum Lumen
Secretory Granule
Nucleus
Nucleoplasm
Membrane
Core-binding Factor Complex
Molecular Function
Hormone Activity
Protein Binding
DNA Binding
Transcription Coactivator Activity
Protein Binding
Sequence-specific DNA Binding
Biological Process
Signal Transduction
Negative Regulation Of Transcription By RNA Polymerase II
Protein Polyubiquitination
Ossification
Osteoblast Differentiation
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Lymphocyte Differentiation
Myeloid Cell Differentiation
Negative Regulation Of CD4-positive, Alpha-beta T Cell Differentiation
Positive Regulation Of CD8-positive, Alpha-beta T Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Cell Maturation
Definitive Hemopoiesis
Pathways
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)
Transcriptional regulation by RUNX2
Transcriptional regulation by RUNX2
RUNX1 regulates estrogen receptor mediated transcription
Regulation of RUNX1 Expression and Activity
RUNX1 regulates expression of components of tight junctions
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RUNX1 regulates transcription of genes involved in differentiation of HSCs
RUNX1 regulates transcription of genes involved in differentiation of HSCs
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
RUNX1 regulates transcription of genes involved in BCR signaling
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
RUNX1 regulates transcription of genes involved in interleukin signaling
RUNX1 regulates transcription of genes involved in WNT signaling
Regulation of RUNX2 expression and activity
Regulation of RUNX2 expression and activity
RUNX2 regulates osteoblast differentiation
RUNX2 regulates osteoblast differentiation
RUNX2 regulates chondrocyte maturation
RUNX2 regulates bone development
RUNX2 regulates genes involved in cell migration
RUNX2 regulates genes involved in cell migration
RUNX2 regulates genes involved in differentiation of myeloid cells
Regulation of RUNX3 expression and activity
RUNX3 Regulates Immune Response and Cell Migration
RUNX3 Regulates Immune Response and Cell Migration
RUNX3 regulates RUNX1-mediated transcription
RUNX3 regulates p14-ARF
Estrogen-dependent gene expression
Transcriptional regulation of granulopoiesis
Drugs
Diseases
GWAS
Metabolite levels (
23823483
)
Uterine fibroid number (single vs multiple) (
30196971
)
Appendicular lean mass (
33097823
)
Mean corpuscular hemoglobin (
27863252
)
Interacting Genes
34 interacting genes:
ACACA
ANXA7
APP
ATXN2
CBFB
CCDC92
CDKN1A
FGFR3
LRRK1
LRRK2
MARK3
MFHAS1
MGLL
MOGS
OGG1
PKN2
POLD1
POLR2E
PRAG1
PTEN
RAC2
RAP1B
RCC1
RXRG
S100A8
SAFB2
SLC25A6
TAFAZZIN
TK1
TUBB2A
TWF2
UBQLN1
UBTF
YLPM1
9 interacting genes:
CBFA2T2
CHGB
CHRM5
COPRS
RAB2A
RNF7
RUNX1
RUNX2
RUNX3
Entrez ID
1114
865
HPRD ID
07512
00418
Ensembl ID
ENSG00000089199
ENSG00000067955
Uniprot IDs
P05060
Q13951
PDB IDs
1CL3
1E50
1H9D
4N9F
6NIL
6P59
6VGD
6VGE
6VGG
8CX0
8CX1
8CX2
8E40
8FVI
8FVJ
8H0I
8J62
8SZK
Enriched GO Terms of Interacting Partners
?
Nucleotide Binding
Cytoplasm
Negative Regulation Of Protein Localization To Nucleus
Intracellular Signal Transduction
Regulation Of Toll-like Receptor Signaling Pathway
Regulation Of Reactive Oxygen Species Metabolic Process
Cellular Response To Manganese Ion
Regulation Of Nervous System Process
Modulation Of Excitatory Postsynaptic Potential
Negative Regulation Of Excitatory Postsynaptic Potential
GTP Binding
Leukocyte Aggregation
RAGE Receptor Binding
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Intracellular Signal Transduction
Regulation Of Signal Transduction
Response To Manganese Ion
Identical Protein Binding
Regulation Of Developmental Growth
Regulation Of Mitotic Cell Cycle
Protein Kinase Activity
Golgi-associated Vesicle
Positive Regulation Of ERK1 And ERK2 Cascade
Regulation Of Intrinsic Apoptotic Signaling Pathway
Regulation Of Cellular Component Organization
Cellular Response To Catecholamine Stimulus
Positive Regulation Of Proteolysis
Response To Catecholamine
Developmental Maturation
ATP Binding
Protein Tetramerization
Membrane Organization
Regulation Of Apoptotic Signaling Pathway
Regulation Of Cell Communication
Regulation Of Signaling
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Mitochondrial Membrane Organization
Extracellular Exosome
Amyloid-beta Complex
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Regulation Of Defense Response
Growth Cone Lamellipodium
Regulation Of Growth
Regulation Of Cell Projection Organization
Regulation Of Cell Activation
Regulation Of Response To Calcium Ion
Positive Regulation Of Excitatory Postsynaptic Potential
Intracellular Signaling Cassette
Positive Regulation Of MAPK Cascade
Amylin Binding
Core-binding Factor Complex
Chondrocyte Differentiation
Positive Regulation Of CD8-positive, Alpha-beta T Cell Differentiation
Regulation Of CD8-positive, Alpha-beta T Cell Differentiation
Positive Regulation Of CD8-positive, Alpha-beta T Cell Activation
Peripheral Nervous System Neuron Development
Ossification
Regulation Of CD8-positive, Alpha-beta T Cell Activation
Negative Regulation Of CD4-positive, Alpha-beta T Cell Differentiation
Hemopoiesis
Negative Regulation Of Alpha-beta T Cell Differentiation
Negative Regulation Of CD4-positive, Alpha-beta T Cell Activation
Transcription Corepressor Binding
Negative Regulation Of Alpha-beta T Cell Activation
Negative Regulation Of T Cell Differentiation
Positive Regulation Of Alpha-beta T Cell Differentiation
Negative Regulation Of Lymphocyte Differentiation
Negative Regulation Of Cell Adhesion
Regulation Of CD4-positive, Alpha-beta T Cell Differentiation
Ligamentous Ossification
Neuron Differentiation
Stem Cell Proliferation
Positive Regulation Of Alpha-beta T Cell Activation
Regulation Of CD4-positive, Alpha-beta T Cell Activation
Osteoblast Fate Commitment
Negative Regulation Of Focal Adhesion Disassembly
Positive Regulation Of Cell Adhesion
Negative Regulation Of Hemopoiesis
Positive Regulation Of T Cell Differentiation
Regulation Of Alpha-beta T Cell Activation
Cardiac Muscle Tissue Regeneration
NEDD8 Ligase Activity
Positive Regulation Of Lymphocyte Differentiation
Negative Regulation Of T Cell Activation
G Protein-coupled Acetylcholine Receptor Activity
Regulation Of Phosphatidylinositol Dephosphorylation
NEDD8 Transferase Activity
Negative Regulation Of DNA-templated Transcription
Sequence-specific Double-stranded DNA Binding
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Leukocyte Cell-cell Adhesion
Phosphocreatine Biosynthetic Process
Negative Regulation Of Lymphocyte Activation
Neuron Development
Negative Regulation Of RNA Metabolic Process
Regulation Of Odontogenesis Of Dentin-containing Tooth
Cell Differentiation
DNA-binding Transcription Factor Binding
Response To Sodium Phosphate
DNA-binding Transcription Factor Activity
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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