CHGB and SAFB2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHGB	SAFB2
Description		chromogranin B	scaffold attachment factor B2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Secretory Granule	Nucleus Nucleoplasm Cytoplasm Nuclear Body Extracellular Exosome
	Molecular Function	Hormone Activity Protein Binding	Nucleic Acid Binding DNA Binding RNA Binding Protein Binding Identical Protein Binding Sequence-specific DNA Binding
	Biological Process	Signal Transduction	Regulation Of Transcription By RNA Polymerase II Regulation Of MRNA Processing Sertoli Cell Differentiation Regulation Of Androgen Receptor Signaling Pathway
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Uterine fibroid number (single vs multiple) ( 30196971)	Creativity ( 32133506) Obsessive-compulsive symptoms ( 26859814) vWF and FVIII levels ( 21810271)
Interacting Genes		34 interacting genes: ACACA ANXA7 APP ATXN2 CBFB CCDC92 CDKN1A FGFR3 LRRK1 LRRK2 MARK3 MFHAS1 MGLL MOGS OGG1 PKN2 POLD1 POLR2E PRAG1 PTEN RAC2 RAP1B RCC1 RXRG S100A8 SAFB2 SLC25A6 TAFAZZIN TK1 TUBB2A TWF2 UBQLN1 UBTF YLPM1	14 interacting genes: CEBPA CHGB ERBB2 ESR1 FNTA FUS FXR1 GIT2 RNF10 SAFB SIRPA SORBS3 SUMO2 ZSCAN18
Entrez ID		1114	9667
HPRD ID		07512	06424
Ensembl ID		ENSG00000089199	ENSG00000130254
Uniprot IDs		P05060	Q14151
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleotide Binding Cytoplasm Negative Regulation Of Protein Localization To Nucleus Intracellular Signal Transduction Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Reactive Oxygen Species Metabolic Process Cellular Response To Manganese Ion Regulation Of Nervous System Process Modulation Of Excitatory Postsynaptic Potential Negative Regulation Of Excitatory Postsynaptic Potential GTP Binding Leukocyte Aggregation RAGE Receptor Binding Positive Regulation Of Intracellular Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Response To Manganese Ion Identical Protein Binding Regulation Of Developmental Growth Regulation Of Mitotic Cell Cycle Protein Kinase Activity Golgi-associated Vesicle Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Cellular Component Organization Cellular Response To Catecholamine Stimulus Positive Regulation Of Proteolysis Response To Catecholamine Developmental Maturation ATP Binding Protein Tetramerization Membrane Organization Regulation Of Apoptotic Signaling Pathway Regulation Of Cell Communication Regulation Of Signaling Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Mitochondrial Membrane Organization Extracellular Exosome Amyloid-beta Complex Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Defense Response Growth Cone Lamellipodium Regulation Of Growth Regulation Of Cell Projection Organization Regulation Of Cell Activation Regulation Of Response To Calcium Ion Positive Regulation Of Excitatory Postsynaptic Potential Intracellular Signaling Cassette Positive Regulation Of MAPK Cascade Amylin Binding	Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Positive Regulation Of Rho Protein Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Intracellular Signal Transduction Positive Regulation Of Small GTPase Mediated Signal Transduction Estrogen Receptor Signaling Pathway Presynaptic Cytosol Postsynaptic Cytosol Regulation Of Inflammatory Response Neuromuscular Junction Development Chromatin Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Molecular Condensate Scaffold Activity RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Peptide Pheromone Maturation Presynapse Glutamatergic Synapse Regulation Of Primary Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Cell Development Regulation Of Metabolic Process Regulation Of Signal Transduction Receptor Tyrosine Kinase Binding Regulation Of Nitric Oxide Metabolic Process Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Response To Vitamin B2 C/EBP Complex ERBB3:ERBB2 Complex Protein-containing Complex Localization CAAX-protein Geranylgeranyltransferase Activity CAAX-protein Geranylgeranyltransferase Complex Protein Farnesyltransferase Activity Protein Farnesyltransferase Complex Cellular Response To Interleukin-12 Negative Regulation Of Multicellular Organismal Process Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Negative Regulation Of MRNA Catabolic Process Positive Regulation Of Metabolic Process
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