CASK and C16orf70

Number of citations of the paper that reports this interaction (PMID 9822620)
43

Data Source:
BioGRID (pull down)

		CASK	C16orf70
Gene Name		calcium/calmodulin-dependent serine protein kinase (MAGUK family)	chromosome 16 open reading frame 70
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Basement Membrane Nuclear Lamina Nucleolus Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Focal Adhesion Actin Cytoskeleton Basolateral Plasma Membrane Nuclear Matrix Presynaptic Membrane Ciliary Membrane
	Molecular Function	Guanylate Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding Calmodulin Binding ATP Binding Neurexin Family Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Cell-matrix Adhesion Protein Phosphorylation Cell Adhesion Negative Regulation Of Keratinocyte Proliferation Extracellular Matrix Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleotide Phosphorylation Negative Regulation Of Wound Healing Calcium Ion Import Positive Regulation Of Calcium Ion Import Negative Regulation Of Cellular Response To Growth Factor Stimulus
Pathways		Syndecan interactions Nephrin interactions Non-integrin membrane-ECM interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		60 interactors: APBA1 ATP2B4 BNIP3L C16orf70 CADM1 CASKIN1 CDK9 CNTNAP2 CNTNAP4 DFNB31 DLG1 DLG4 DUSP3 ELL2 EPB41 EPS8 ERBB2IP F11R FCHSD2 GCNT3 GLS2 GRIK2 GRIN2A HGS ID1 IL15RA IL18 KCNA4 KCNJ12 KCNJ2 KCNJ4 LIN7A LIN7B MARS MLLT6 NPHS1 NRXN1 NRXN2 NRXN3 P2RX7 PARK2 PCBP2 PCM1 PLK2 PRKD2 PTGS2 RAB3A RPH3A SDC1 SDC2 SDC3 SDC4 SH2D4A SMEK1 SRPK2 TANC1 TBR1 TRIM22 TSPYL2 WNT7B	5 interactors: APP ATXN3 BCAS3 CASK KIF17
Entrez ID		8573	80262
HPRD ID		02164	17460
Ensembl ID		ENSG00000147044	ENSG00000125149
Uniprot IDs		O14936	Q9BSU1
PDB IDs		1KGD 1KWA 1ZL8 3C0G 3C0H 3C0I 3MFR 3MFS 3MFT 3MFU 3TAC
Enriched GO Terms of Interacting Partners?		Synaptic Transmission Signaling Cell Communication Cell-cell Signaling Regulation Of Neurotransmitter Levels Learning Vocalization Behavior Neurotransmitter Secretion Neurotransmitter Transport Single-organism Behavior Learning Or Memory Behavior Cognition Establishment Or Maintenance Of Apical/basal Cell Polarity Cellular Protein Localization Cellular Localization Response To External Stimulus Anatomical Structure Development Social Behavior Cellular Component Assembly Regulation Of Synaptic Transmission System Development Regulation Of Cellular Component Organization Response To Stimulus Synapse Organization Regulation Of Grooming Behavior Regulation Of Organelle Organization Protein Localization To Membrane Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Response To Abiotic Stimulus Multicellular Organismal Development Regulation Of Ion Transport Protein Localization Secretion By Cell Membrane Depolarization Developmental Process Anatomical Structure Morphogenesis Neurological System Process Maintenance Of Apical/basal Cell Polarity Cell Adhesion Membrane Organization Receptor Localization To Synapse Regulation Of Cellular Localization Synapse Assembly Regulation Of Signaling Positive Regulation Of Transport Angiogenesis Regulation Of Intracellular Signal Transduction Secretion Positive Regulation Of Exosomal Secretion	Regulation Of Cell-substrate Adhesion Microtubule-based Process Negative Regulation Of Cell-matrix Adhesion Negative Regulation Of Cell-substrate Adhesion Regulation Of Cell Adhesion System Development Regulation Of Cell-matrix Adhesion Multicellular Organismal Development Anatomical Structure Development Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Developmental Process Negative Regulation Of Cell Adhesion Positive Regulation Of Transcription From RNA Polymerase II Promoter Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Positive Regulation Of Transcription, DNA-templated Microtubule-based Movement Activation Of Cdc42 GTPase Activity Neuron Remodeling Monoubiquitinated Protein Deubiquitination Vesicle-mediated Transport Negative Regulation Of Rho GTPase Activity Positive Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Macromolecule Biosynthetic Process Extracellular Matrix Organization Extracellular Structure Organization Negative Regulation Of Keratinocyte Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Hydrolase Activity Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Calcium Ion Import Misfolded Or Incompletely Synthesized Protein Catabolic Process Cellular Response To Misfolded Protein Positive Regulation Of Cdc42 GTPase Activity Microtubule Cytoskeleton Organization Negative Regulation Of Ras GTPase Activity Response To Misfolded Protein Negative Regulation Of Focal Adhesion Assembly Protein K48-linked Deubiquitination Posttranscriptional Regulation Of Gene Expression Protein K63-linked Deubiquitination Cellular Copper Ion Homeostasis Protein Complex Localization Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Keratinocyte Proliferation Copper Ion Homeostasis
Tagcloud ?		channels clustering coclusters coimmunoprecipitates colocalizes constituent cooh enzymatic fact gk gkap guanylate heterologous homology isolation junction lin maguk nh2 obscure organization pdz postsynaptic psd sap90 sh3 synaptic termed zo
Tagcloud (Difference) ?		channels clustering coclusters coimmunoprecipitates colocalizes constituent cooh enzymatic fact gk gkap guanylate heterologous homology isolation junction lin maguk nh2 obscure organization pdz postsynaptic psd sap90 sh3 synaptic termed zo
Tagcloud (Intersection) ?