C16orf70 and BCAS3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		C16orf70	BCAS3
Gene Name		chromosome 16 open reading frame 70	breast carcinoma amplified sequence 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Cytoplasm Cytoplasmic Microtubule Cell Leading Edge Transcriptionally Active Chromatin Intermediate Filament Cytoskeleton Cell Periphery
	Molecular Function	Protein Binding	Chromatin Binding Protein Binding Transcription Factor Binding Acetyltransferase Activator Activity Histone Acetyltransferase Binding Nuclear Hormone Receptor Binding Histone Binding Beta-tubulin Binding
	Biological Process		Angiogenesis Transcription, DNA-templated Golgi Organization Positive Regulation Of Endothelial Cell Migration Vesicle-mediated Transport Microtubule Organizing Center Organization Activation Of Cdc42 GTPase Activity Negative Regulation Of Rho GTPase Activity Tube Formation Response To Starvation Positive Regulation Of Catalytic Activity Positive Regulation Of Cdc42 GTPase Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Filopodium Assembly Negative Regulation Of Focal Adhesion Assembly Cellular Response To Estrogen Stimulus Positive Regulation Of Intracellular Protein Transport Regulation Of Establishment Of Cell Polarity Positive Regulation Of Actin Cytoskeleton Reorganization
Pathways
Drugs
Diseases
GWAS			Alzheimer's disease (cognitive decline) ( 23535033) Chronic kidney disease ( 20383146) Height ( 18391951) Immune reponse to smallpox (secreted IL-2) ( 22610502) Obesity-related traits ( 23251661) Renal function-related traits (BUN) ( 22797727) Renal function-related traits (eGRFcrea) ( 22797727) Renal function-related traits (sCR) ( 22797727) Urate levels ( 23263486) Vertical cup-disc ratio ( 20548946)
Protein-Protein Interactions		5 interactors: APP ATXN3 BCAS3 CASK KIF17	5 interactors: C16orf70 CDC23 CTBP1 CTBP2 ZDHHC17
Entrez ID		80262	54828
HPRD ID		17460	06313
Ensembl ID		ENSG00000125149	ENSG00000141376
Uniprot IDs		Q9BSU1	Q05D99 Q9H6U6
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cell-substrate Adhesion Microtubule-based Process Negative Regulation Of Cell-matrix Adhesion Negative Regulation Of Cell-substrate Adhesion Regulation Of Cell Adhesion System Development Regulation Of Cell-matrix Adhesion Multicellular Organismal Development Anatomical Structure Development Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Developmental Process Negative Regulation Of Cell Adhesion Positive Regulation Of Transcription From RNA Polymerase II Promoter Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Positive Regulation Of Transcription, DNA-templated Microtubule-based Movement Activation Of Cdc42 GTPase Activity Neuron Remodeling Monoubiquitinated Protein Deubiquitination Vesicle-mediated Transport Negative Regulation Of Rho GTPase Activity Positive Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Macromolecule Biosynthetic Process Extracellular Matrix Organization Extracellular Structure Organization Negative Regulation Of Keratinocyte Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Hydrolase Activity Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Calcium Ion Import Misfolded Or Incompletely Synthesized Protein Catabolic Process Cellular Response To Misfolded Protein Positive Regulation Of Cdc42 GTPase Activity Microtubule Cytoskeleton Organization Negative Regulation Of Ras GTPase Activity Response To Misfolded Protein Negative Regulation Of Focal Adhesion Assembly Protein K48-linked Deubiquitination Posttranscriptional Regulation Of Gene Expression Protein K63-linked Deubiquitination Cellular Copper Ion Homeostasis Protein Complex Localization Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Keratinocyte Proliferation Copper Ion Homeostasis	White Fat Cell Differentiation Viral Genome Replication Negative Regulation Of Chromosome Organization Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification Fat Cell Differentiation Viral Life Cycle Regulation Of Chromosome Organization Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Chromatin Binding Metaphase/anaphase Transition Of Mitotic Cell Cycle Negative Regulation Of Histone H4 Acetylation Regulation Of Exit From Mitosis Negative Regulation Of Cellular Metabolic Process Regulation Of Histone H4 Acetylation Viral Process Lipoprotein Transport Positive Regulation Of Histone Deacetylation Magnesium Ion Transport Negative Regulation Of Histone Acetylation Protein K11-linked Ubiquitination Negative Regulation Of Peptidyl-lysine Acetylation Negative Regulation Of Protein Acetylation Positive Regulation Of Protein Deacetylation Mitotic Metaphase Plate Congression Negative Regulation Of Cell Proliferation Positive Regulation Of Cellular Metabolic Process Protein Palmitoylation Metaphase Plate Congression Mitotic Spindle Assembly Checkpoint Regulation Of Histone Deacetylation Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Chromosome Segregation Establishment Of Chromosome Localization Negative Regulation Of Protein Metabolic Process Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Histone Acetylation Regulation Of Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Organelle Organization Regulation Of Protein Deacetylation Regulation Of Cell Cycle Cellular Protein Modification Process Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Chromosome Organization
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