BLZF1 and GEM

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BLZF1	GEM
Description		basic leucine zipper nuclear factor 1	GTP binding protein overexpressed in skeletal muscle
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cis-Golgi Network Membrane	Nucleus Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Midbody Spindle Midzone Mitotic Spindle
	Molecular Function	Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding	Nucleotide Binding Magnesium Ion Binding GTPase Activity Calcium Channel Regulator Activity Protein Binding Calmodulin Binding GTP Binding GDP Binding
	Biological Process	Golgi Organization Protein Transport Vesicle-mediated Transport Golgi To Plasma Membrane Protein Transport	Mitotic Cell Cycle Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway Chromosome Organization Metaphase Chromosome Alignment
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization	NPAS4 regulates expression of target genes
Drugs
Diseases
GWAS			Carotid plaque burden ( 28282560) Coronary artery disease ( 29212778 33020668) Pulse pressure ( 30578418)
Interacting Genes		100 interacting genes: AKAP9 AMOTL2 ANKS1A AQP1 BAG4 BANP BCL6 BEX2 CARD9 CCDC120 CCDC33 CCNH CDC37 CDK18 CFAP206 CHCHD3 CINP CKS2 DNMT3L ENKD1 ERCC3 EWSR1 EXOC8 FAM124B FAM90A1 FBF1 FHL2 FRMD6 FRS3 GEM GORASP2 HCLS1 HDAC4 HOXA1 HOXC8 IGFN1 IKZF3 IL16 IQUB KANK2 KAT5 KCTD9 KDM1A KIF9 KLHL38 LGALS14 LMO1 LMO2 LMO3 LNX1 MID2 MISP MKRN3 NTAQ1 OAZ3 PCDHB12 PIK3R3 PKN1 POLR1C PRKAB2 PRMT6 PRPF18 PSMA1 PTPN11 RAB2A RAB2B RAB39A RANBP3 RHOJ SCNM1 SMAD3 SMARCB1 SPRED1 SRA1 SSX2 SUV39H2 SYT17 TBC1D22B TBC1D7 TCAP TCF19 TEKT4 TNS2 TRAPPC2L TRIM59 TSC22D4 TSTD2 TTC23 TXNDC5 USHBP1 VPS28 ZBTB16 ZBTB24 ZGPAT ZMAT1 ZNF124 ZNF410 ZNF688 ZNF76 ZZZ3	128 interacting genes: A2M AHCYL1 ANKRD36B APOH ASB15 BEGAIN BLOC1S2 BLZF1 BMP1 CACNB3 CALM1 CARD9 CCDC102B CCDC125 CCDC88B CDR2 CEP70 CLDN15 CLEC4G COG6 COG8 CTSL CYSRT1 DBF4B DEUP1 DISC1 DRC4 ECSIT EFHC2 EXOSC8 FSAF1 GADD45GIP1 GMIP GOLGA2 GOLGA6L9 GOPC GPRASP3 HOOK2 HSF2BP IHO1 IKZF3 INCA1 INO80E INSC ISCA2 KATNBL1 KCTD9 KIFC3 KLC3 KRT31 KRT34 KRT36 KRT40 KRT6A KRT83 KRTAP10-3 KRTAP10-7 KRTAP10-8 LIMS1 LRP2BP LZTS2 MCRS1 MESD MGLL MID2 MIPOL1 MKRN3 MORN3 MSS51 MTUS2 MYOG NDUFAF3 NDUFB7 NDUFS8 NOTCH2NLA OIP5 PBX4 PDLIM7 PIH1D1 PLAGL2 PLEKHF2 PNMA1 POF1B PRDM14 PRDM6 RNF7 RUNDC3A SDHB SNAP91 SORBS3 SPAG5 SPATA6 SSX2IP TBC1D3B TBC1D3G TCF4 TFIP11 TGM7 TLE5 TP53BP2 TRAF1 TRAF2 TRIM10 TRIM23 TRIM27 TRIM32 TRIM54 TRIM69 USH1G USHBP1 VIM VPS28 VPS52 VTN WWOX YBEY YPEL3 YWHAB ZBTB42 ZC4H2 ZMAT5 ZNF20 ZNF552 ZNF655 ZNF688 ZNF774 ZRANB1 ZSCAN9
Entrez ID		8548	2669
HPRD ID		16367	11553
Ensembl ID		ENSG00000117475	ENSG00000164949
Uniprot IDs		Q9H2G9	P55040
PDB IDs			2CJW 2G3Y 2HT6
Enriched GO Terms of Interacting Partners?		Protein Binding Nucleus DNA-binding Transcription Factor Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Transcription Coactivator Activity Regulation Of RNA Metabolic Process Zinc Ion Binding Negative Regulation Of Transcription By RNA Polymerase II	Identical Protein Binding Protein Binding Keratin Filament Intermediate Filament Cytoskeleton Intermediate Filament Organization Microtubule Binding Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Microtubule Cytoskeleton Organization Zinc Ion Binding Organelle Organization TORC1 Complex Assembly Centrosome Negative Regulation Of Viral Transcription Suppression Of Viral Release By Host Microtubule-based Process Supramolecular Fiber Organization Ubiquitin Protein Ligase Activity Regulation Of Viral Transcription Protein Localization To Cytoskeleton
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