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IGSF21 and MAD2L1BP
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
IGSF21
MAD2L1BP
Gene Name
immunoglobin superfamily, member 21
MAD2L1 binding protein
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Nucleus
Nucleolus
Cytoplasm
Spindle
Intracellular Membrane-bounded Organelle
Molecular Function
Protein Binding
Biological Process
Mitotic Cell Cycle Checkpoint
Regulation Of Exit From Mitosis
Pathways
Drugs
Diseases
GWAS
Diabetic retinopathy (
21441570
)
Erectile dysfunction and prostate cancer treatment (
20932654
)
Protein-Protein Interactions
32 interactors:
ALDH2
ANXA3
ATF3
BCR
BTBD2
CRCT1
DGKD
EPB41L3
ERH
ETHE1
GADD45A
GIPC2
GSK3B
GSTM4
HSPB1
KRAS
MAD2L1BP
NACA
NREP
PAEP
PAFAH1B3
PCDHA4
PRMT1
PSMD11
RPP14
S100A8
SEPHS1
SERPINB9
SULT1E1
TMSB4X
TRBV2
UBE2V2
15 interactors:
EEF1A1
HOMEZ
IGSF21
INPP5K
KAT5
KIAA1377
KRT15
LRIF1
MAD2L1
NMI
PTN
SETDB1
TP53
TRIP13
ZBTB14
Entrez ID
84966
9587
HPRD ID
11309
10065
Ensembl ID
ENSG00000117154
ENSG00000124688
Uniprot IDs
Q96ID5
Q15013
PDB IDs
2QYF
Enriched GO Terms of Interacting Partners
?
Response To Wounding
Regulation Of Apoptotic Process
Regulation Of Cell Death
Wound Healing
Positive Regulation Of Protein Metabolic Process
Response To Stress
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Cell Death
Negative Regulation Of Catalytic Activity
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Catalytic Activity
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Proteolysis
Negative Regulation Of Transferase Activity
Response To Stimulus
Developmental Process
Xenobiotic Metabolic Process
Cellular Response To Xenobiotic Stimulus
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Response To Xenobiotic Stimulus
Regulation Of Protein Metabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
Apoptotic Process
Epidermal Growth Factor Receptor Signaling Pathway
Nervous System Development
ERBB Signaling Pathway
Regulation Of Proteolysis
Programmed Cell Death
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cell Death
Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development
Death
Cellular Response To Stimulus
Blood Coagulation
Platelet Activation
Hemostasis
Regulation Of Protein Kinase Activity
Response To Biotic Stimulus
Multicellular Organismal Development
Positive Regulation Of Catalytic Activity
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Protein Kinase Activity
Positive Regulation Of Rac GTPase Activity
Positive Regulation Of Endothelial Cell Migration
Regulation Of Neuronal Synaptic Plasticity
Regulation Of Kinase Activity
Positive Regulation Of Protein Catabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Growth
Transcription, DNA-templated
RNA Biosynthetic Process
RNA Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Nucleic Acid-templated Transcription
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Negative Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
DNA Damage Response, Signal Transduction Resulting In Transcription
Gene Expression
Cellular Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
Macromolecule Biosynthetic Process
Biosynthetic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Double-strand Break Repair
Cellular Response To Epidermal Growth Factor Stimulus
Response To Epidermal Growth Factor
Chromosome Organization
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Renal Water Transport
Negative Regulation Of Catalytic Activity
DNA Damage Response, Signal Transduction By P53 Class Mediator
Organelle Organization
Regulation Of Transcription, DNA-templated
Nitrogen Compound Metabolic Process
Negative Regulation Of Macromitophagy
Oligodendrocyte Apoptotic Process
Signal Transduction In Response To DNA Damage
Negative Regulation Of DNA Metabolic Process
Negative Regulation Of Helicase Activity
Negative Regulation Of Glycogen (starch) Synthase Activity
Signal Transduction By P53 Class Mediator
Negative Regulation Of APC-Cdc20 Complex Activity
Cell Cycle Process
Regulation Of Gene Expression
In Utero Embryonic Development
Regulation Of Transcription From RNA Polymerase II Promoter
Response To Ionizing Radiation
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate
Tagcloud
?
allelic
analytical
coexpression
coordinator
datasets
esrp2
exemplifies
fgfr2
gbp1
glud2
illustrates
impairs
indels
landscape
maged1
mtap
overlaid
principle
proof
r353q
revealing
signatures
slc30a8
splicing
substitution
tbnc
tnbc
tpp1
transcriptome
Tagcloud (Difference)
?
allelic
analytical
coexpression
coordinator
datasets
esrp2
exemplifies
fgfr2
gbp1
glud2
illustrates
impairs
indels
landscape
maged1
mtap
overlaid
principle
proof
r353q
revealing
signatures
slc30a8
splicing
substitution
tbnc
tnbc
tpp1
transcriptome
Tagcloud (Intersection)
?