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IGSF21 and ETHE1
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
IGSF21
ETHE1
Gene Name
immunoglobin superfamily, member 21
ethylmalonic encephalopathy 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Nucleoplasm
Cytoplasm
Mitochondrion
Mitochondrial Matrix
Molecular Function
Iron Ion Binding
Sulfur Dioxygenase Activity
Biological Process
Sulfur Amino Acid Metabolic Process
Sulfur Amino Acid Catabolic Process
Glutathione Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Small Molecule Metabolic Process
Sulfide Oxidation, Using Sulfide:quinone Oxidoreductase
Hydrogen Sulfide Metabolic Process
Pathways
Sulfide oxidation to sulfate
Degradation of cysteine and homocysteine
Sulfur amino acid metabolism
Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS
Diabetic retinopathy (
21441570
)
Erectile dysfunction and prostate cancer treatment (
20932654
)
Protein-Protein Interactions
32 interactors:
ALDH2
ANXA3
ATF3
BCR
BTBD2
CRCT1
DGKD
EPB41L3
ERH
ETHE1
GADD45A
GIPC2
GSK3B
GSTM4
HSPB1
KRAS
MAD2L1BP
NACA
NREP
PAEP
PAFAH1B3
PCDHA4
PRMT1
PSMD11
RPP14
S100A8
SEPHS1
SERPINB9
SULT1E1
TMSB4X
TRBV2
UBE2V2
5 interactors:
APP
ATP6V1H
IGSF21
LRIF1
RELA
Entrez ID
84966
23474
HPRD ID
11309
09764
Ensembl ID
ENSG00000117154
ENSG00000105755
Uniprot IDs
Q96ID5
B2RCZ7
M0QXB5
O95571
PDB IDs
Enriched GO Terms of Interacting Partners
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Response To Wounding
Regulation Of Apoptotic Process
Regulation Of Cell Death
Wound Healing
Positive Regulation Of Protein Metabolic Process
Response To Stress
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Cell Death
Negative Regulation Of Catalytic Activity
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Catalytic Activity
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Proteolysis
Negative Regulation Of Transferase Activity
Response To Stimulus
Developmental Process
Xenobiotic Metabolic Process
Cellular Response To Xenobiotic Stimulus
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Response To Xenobiotic Stimulus
Regulation Of Protein Metabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
Apoptotic Process
Epidermal Growth Factor Receptor Signaling Pathway
Nervous System Development
ERBB Signaling Pathway
Regulation Of Proteolysis
Programmed Cell Death
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cell Death
Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development
Death
Cellular Response To Stimulus
Blood Coagulation
Platelet Activation
Hemostasis
Regulation Of Protein Kinase Activity
Response To Biotic Stimulus
Multicellular Organismal Development
Positive Regulation Of Catalytic Activity
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Protein Kinase Activity
Positive Regulation Of Rac GTPase Activity
Positive Regulation Of Endothelial Cell Migration
Regulation Of Neuronal Synaptic Plasticity
Regulation Of Kinase Activity
Positive Regulation Of Protein Catabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Growth
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Acetaldehyde Metabolic Process
Transition Metal Ion Homeostasis
Positive Regulation Of Schwann Cell Differentiation
Synaptic Growth At Neuromuscular Junction
Intracellular Receptor Signaling Pathway
Collateral Sprouting In Absence Of Injury
Regulation Of Schwann Cell Differentiation
Response To Cobalamin
Collateral Sprouting
Axon Midline Choice Point Recognition
Response To Insulin
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Positive Regulation Of MiRNA Metabolic Process
Cellular Response To Peptide Hormone Stimulus
Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway
Axon Choice Point Recognition
Cellular Response To Peptide
Response To Light Stimulus
Cellular Response To Nicotine
Positive Regulation Of Interleukin-12 Biosynthetic Process
Neuron Remodeling
Cellular Metal Ion Homeostasis
Regulation Of MiRNA Metabolic Process
Response To Oxidative Stress
Vacuolar Acidification
Cellular Cation Homeostasis
Response To Radiation
Response To Peptide Hormone
Cellular Ion Homeostasis
Regulation Of Interleukin-12 Biosynthetic Process
Cellular Response To Organonitrogen Compound
Metal Ion Homeostasis
Response To Peptide
Response To Muramyl Dipeptide
Response To UV-B
Membrane Protein Intracellular Domain Proteolysis
Cellular Chemical Homeostasis
Cellular Copper Ion Homeostasis
Viral Process
Ion Homeostasis
Intracellular PH Reduction
Cellular Response To Hormone Stimulus
PH Reduction
Copper Ion Homeostasis
Suckling Behavior
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Regulation Of Defense Response To Virus By Virus
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Cellular Response To Interleukin-6
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Tagcloud (Intersection)
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