IGSF21 and SEPHS1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		IGSF21	SEPHS1
Gene Name		immunoglobin superfamily, member 21	selenophosphate synthetase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region	Cytoplasm Plasma Membrane Nuclear Membrane
	Molecular Function		Selenide, Water Dikinase Activity Protein Binding ATP Binding GTP Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process		Cellular Protein Modification Process Phosphorylation
Pathways
Drugs
Diseases
GWAS		Diabetic retinopathy ( 21441570) Erectile dysfunction and prostate cancer treatment ( 20932654)
Protein-Protein Interactions		32 interactors: ALDH2 ANXA3 ATF3 BCR BTBD2 CRCT1 DGKD EPB41L3 ERH ETHE1 GADD45A GIPC2 GSK3B GSTM4 HSPB1 KRAS MAD2L1BP NACA NREP PAEP PAFAH1B3 PCDHA4 PRMT1 PSMD11 RPP14 S100A8 SEPHS1 SERPINB9 SULT1E1 TMSB4X TRBV2 UBE2V2	10 interactors: C14orf1 C9orf9 CRMP1 GBP2 IGSF21 QRICH1 SAT1 SLC35F6 UNC119 ZBTB25
Entrez ID		84966	22929
HPRD ID		11309	02944
Ensembl ID		ENSG00000117154	ENSG00000086475
Uniprot IDs		Q96ID5	P49903
PDB IDs			3FD5 3FD6
Enriched GO Terms of Interacting Partners?		Response To Wounding Regulation Of Apoptotic Process Regulation Of Cell Death Wound Healing Positive Regulation Of Protein Metabolic Process Response To Stress Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Negative Regulation Of Catalytic Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Catalytic Activity Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Proteolysis Negative Regulation Of Transferase Activity Response To Stimulus Developmental Process Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Response To Xenobiotic Stimulus Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Protein Catabolic Process Apoptotic Process Epidermal Growth Factor Receptor Signaling Pathway Nervous System Development ERBB Signaling Pathway Regulation Of Proteolysis Programmed Cell Death Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Death Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Death Cellular Response To Stimulus Blood Coagulation Platelet Activation Hemostasis Regulation Of Protein Kinase Activity Response To Biotic Stimulus Multicellular Organismal Development Positive Regulation Of Catalytic Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Protein Kinase Activity Positive Regulation Of Rac GTPase Activity Positive Regulation Of Endothelial Cell Migration Regulation Of Neuronal Synaptic Plasticity Regulation Of Kinase Activity Positive Regulation Of Protein Catabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Growth	Negative Regulation Of Clathrin-mediated Endocytosis Spermidine Acetylation Negative Regulation Of Caveolin-mediated Endocytosis Cytokinesis, Completion Of Separation Putrescine Catabolic Process Oxalate Transport Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Polyamine Catabolic Process 3'-phosphoadenosine 5'-phosphosulfate Biosynthetic Process Regulation Of Caveolin-mediated Endocytosis Mitotic Cytokinetic Process Pyrimidine Nucleobase Catabolic Process
Tagcloud ?			adjustment amongst around auckland cd crohn detailed elsewhere interact kingdom lowest making namely ng nucleotide optimal polymorphisms rs1553153 rs17529609 rs7901303 selenium sepsecs serum snps united whilst world zealand zealanders
Tagcloud (Difference) ?			adjustment amongst around auckland cd crohn detailed elsewhere interact kingdom lowest making namely ng nucleotide optimal polymorphisms rs1553153 rs17529609 rs7901303 selenium sepsecs serum snps united whilst world zealand zealanders
Tagcloud (Intersection) ?