Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
IGSF21 and TMSB4X
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
HPRD
(two hybrid)
IGSF21
TMSB4X
Gene Name
immunoglobin superfamily, member 21
thymosin beta 4, X-linked
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Extracellular Region
Cytoskeleton
Platelet Alpha Granule Lumen
Molecular Function
Actin Monomer Binding
Protein Binding
Poly(A) RNA Binding
Biological Process
Platelet Degranulation
Actin Filament Organization
Blood Coagulation
Platelet Activation
Sequestering Of Actin Monomers
Pathways
Response to elevated platelet cytosolic Ca2+
Platelet degranulation
Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS
Diabetic retinopathy (
21441570
)
Erectile dysfunction and prostate cancer treatment (
20932654
)
Protein-Protein Interactions
32 interactors:
ALDH2
ANXA3
ATF3
BCR
BTBD2
CRCT1
DGKD
EPB41L3
ERH
ETHE1
GADD45A
GIPC2
GSK3B
GSTM4
HSPB1
KRAS
MAD2L1BP
NACA
NREP
PAEP
PAFAH1B3
PCDHA4
PRMT1
PSMD11
RPP14
S100A8
SEPHS1
SERPINB9
SULT1E1
TMSB4X
TRBV2
UBE2V2
29 interactors:
ACTA1
ACTA2
ACTB
ACTG1
ALAS1
ANXA7
APLP1
CDKN1A
FAM118B
GRB7
IGSF21
ILK
KRT13
KRT15
KRT31
KRT40
LIMS1
PNMA1
PPP4C
RAD21
RBPMS
SCHIP1
SMN1
TAF1D
TGM2
TK1
TRIM23
TRIM27
TRIP6
Entrez ID
84966
7114
HPRD ID
11309
02153
Ensembl ID
ENSG00000117154
ENSG00000205542
Uniprot IDs
Q96ID5
A2VCK8
P62328
Q0P5T0
PDB IDs
1UY5
3TU5
Enriched GO Terms of Interacting Partners
?
Response To Wounding
Regulation Of Apoptotic Process
Regulation Of Cell Death
Wound Healing
Positive Regulation Of Protein Metabolic Process
Response To Stress
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Cell Death
Negative Regulation Of Catalytic Activity
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Catalytic Activity
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Proteolysis
Negative Regulation Of Transferase Activity
Response To Stimulus
Developmental Process
Xenobiotic Metabolic Process
Cellular Response To Xenobiotic Stimulus
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Response To Xenobiotic Stimulus
Regulation Of Protein Metabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
Apoptotic Process
Epidermal Growth Factor Receptor Signaling Pathway
Nervous System Development
ERBB Signaling Pathway
Regulation Of Proteolysis
Programmed Cell Death
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cell Death
Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development
Death
Cellular Response To Stimulus
Blood Coagulation
Platelet Activation
Hemostasis
Regulation Of Protein Kinase Activity
Response To Biotic Stimulus
Multicellular Organismal Development
Positive Regulation Of Catalytic Activity
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Protein Kinase Activity
Positive Regulation Of Rac GTPase Activity
Positive Regulation Of Endothelial Cell Migration
Regulation Of Neuronal Synaptic Plasticity
Regulation Of Kinase Activity
Positive Regulation Of Protein Catabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Growth
Cellular Component Assembly
Cell Junction Assembly
Platelet Aggregation
Anatomical Structure Development
Response To Stimulus
Cell Aging
Cell-cell Junction Organization
Hemostasis
Protein Oligomerization
Epithelium Development
Adherens Junction Organization
Developmental Process
Tissue Development
Regulation Of Body Fluid Levels
Cell-matrix Adhesion
Regulation Of Protein Import Into Nucleus
Blood Coagulation
Cellular Response To Stimulus
Platelet Activation
Fetal Process Involved In Parturition
Regulation Of Protein Localization To Nucleus
Cell Adhesion
Negative Regulation Of Neural Precursor Cell Proliferation
Regulation Of Nucleocytoplasmic Transport
Cell-substrate Adhesion
Negative Regulation Of Protein Kinase Activity
Positive Regulation Of Cell-matrix Adhesion
Positive Regulation Of Signal Transduction
Negative Regulation Of Kinase Activity
Multicellular Organismal Development
Retina Homeostasis
Response To Organic Cyclic Compound
Single Organismal Cell-cell Adhesion
Negative Regulation Of Interleukin-2 Secretion
Skeletal Muscle Cell Proliferation
Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine
Skeletal Muscle Fiber Adaptation
Negative Regulation Of Gene Expression
System Development
Regulation Of Intracellular Protein Transport
Phagocytosis
Organ Development
Fc Receptor Signaling Pathway
Negative Regulation Of Gene Expression, Epigenetic
Myofibril Assembly
Cellular Response To Norepinephrine Stimulus
Wound Healing
Negative Regulation Of Transferase Activity
Regulation Of Protein Transport
Protein Complex Assembly
Tagcloud
?
aldo3
bhlhb2
bnip3
bnip31
cdknla
cnn2
cobalt
eno2
exerting
f10
fdr
hk2
itga4
lgals3
mcam
mimicry
mxil
nominal
nppb
pfkp
pkp2
probesets
sap30
selenbpl
singular
u74av2
unsupervised
vegfa
wise
Tagcloud (Difference)
?
aldo3
bhlhb2
bnip3
bnip31
cdknla
cnn2
cobalt
eno2
exerting
f10
fdr
hk2
itga4
lgals3
mcam
mimicry
mxil
nominal
nppb
pfkp
pkp2
probesets
sap30
selenbpl
singular
u74av2
unsupervised
vegfa
wise
Tagcloud (Intersection)
?