MAD2L1BP and NMI

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		MAD2L1BP	NMI
Description		MAD2L1 binding protein	N-myc and STAT interactor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Spindle Cytoskeleton Nuclear Membrane	Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Membrane
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Exit From Mitosis Deactivation Of Mitotic Spindle Assembly Checkpoint	Macrophage Activation Involved In Immune Response Immune System Process Cell Surface Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Cell Population Proliferation Response To Virus Negative Regulation Of Type I Interferon Production Negative Regulation Of Interferon-alpha Production Negative Regulation Of Interferon-beta Production Toll-like Receptor 4 Signaling Pathway Innate Immune Response Regulation Of Innate Immune Response Positive Regulation Of Innate Immune Response Negative Regulation Of Innate Immune Response Positive Regulation Of Inflammatory Response Protein K48-linked Ubiquitination Negative Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Protein K48-linked Ubiquitination
Pathways			SARS-CoV-1 activates/modulates innate immune responses
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		18 interacting genes: ANAPC4 CEP126 EEF1A1 HOMEZ IGSF21 KAT5 KRT15 LRIF1 MAD2L1 MAD2L2 NMI PLK1 PTN SETDB1 TP53 TRIP13 ZBTB14 ZNF202	57 interacting genes: ANKRD13C-DT BRAT1 BRCA1 BRMS1 C1orf216 CDKN2A CDKN2D CNKSR3 CNOT7 COPS7B CYP2E1 EMILIN1 EXOSC5 GCSH GOLGA8EP HDDC3 HGS HOXC9 HSPA8 HSPH1 IFI35 KDM1A LCA5L LSM4 MAD2L1BP MCPH1 MORF4L1 MTMR6 MTMR9 MYC MYCN MYOM3 NECAP2 POMZP3 PSMA1 RYBP SCEL SFR1 SH3GLB2 SINHCAF SNAPC5 SOX10 STAT1 STAT3 STAT4 STAT5A STAT5B STAT6 THAP8 TRAF5 TRIM72 TRIP12 TUBA3C TUBA3E TXLNA TXLNB UBE2I
Entrez ID		9587	9111
HPRD ID		10065	04632
Ensembl ID		ENSG00000124688	ENSG00000123609
Uniprot IDs		Q15013	Q13287
PDB IDs		2QYF 6F0X
Enriched GO Terms of Interacting Partners?		Regulation Of Sister Chromatid Segregation Regulation Of Chromosome Segregation Regulation Of Chromosome Organization Mitotic Spindle Assembly Checkpoint Signaling Negative Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Chromosome Organization Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Mitotic Nuclear Division Chromosome Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Chromosome Separation Negative Regulation Of Mitotic Cell Cycle Regulation Of Ubiquitin-protein Transferase Activity Double-strand Break Repair Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Negative Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Process Regulation Of Mitotic Nuclear Division Establishment Of Mitotic Spindle Orientation Negative Regulation Of Cell Cycle Process Microtubule Cytoskeleton Organization Involved In Mitosis Establishment Of Mitotic Spindle Localization Negative Regulation Of Double-strand Break Repair Regulation Of Mitotic Cell Cycle Negative Regulation Of DNA Metabolic Process Negative Regulation Of DNA Repair Establishment Of Spindle Orientation Regulation Of Nuclear Division Negative Regulation Of Macromolecule Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of DNA Recombination Chromosome Organization Establishment Of Spindle Localization Negative Regulation Of Cell Cycle Nucleus Negative Regulation Of Macromolecule Biosynthetic Process Nucleolus Negative Regulation Of Metabolic Process Negative Regulation Of Ubiquitin Protein Ligase Activity Spindle Localization Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Germ Cell Development Regulation Of Protein Ubiquitination Negative Regulation Of Ubiquitin-protein Transferase Activity Promoter-specific Chromatin Binding Regulation Of Cell Cycle	Nucleoplasm Cell Surface Receptor Signaling Pathway Via JAK-STAT Growth Hormone Receptor Signaling Pathway Via JAK-STAT Cell Surface Receptor Signaling Pathway Via STAT Growth Hormone Receptor Signaling Pathway Interleukin-9-mediated Signaling Pathway Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Cell Population Proliferation RNA Polymerase II Transcription Regulator Complex Negative Regulation Of RNA Metabolic Process Negative Regulation Of Developmental Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Nucleic Acid Metabolic Process Regulation Of Programmed Cell Death Regulation Of Erythrocyte Differentiation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Cell Population Proliferation Development Of Secondary Female Sexual Characteristics Development Of Secondary Male Sexual Characteristics DNA-binding Transcription Factor Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Sin3-type Complex Regulation Of Apoptotic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Positive Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Differentiation DNA-templated Transcription Positive Regulation Of Mesenchymal Cell Proliferation Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Mitotic Cell Cycle Negative Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Development Of Secondary Sexual Characteristics Positive Regulation Of Gene Expression Regulation Of Myeloid Cell Apoptotic Process Positive Regulation Of Metabolic Process
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