TMSB4X and KRT13

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		TMSB4X	KRT13
Description		thymosin beta 4 X-linked	keratin 13
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Cytosol Cytoskeleton Platelet Alpha Granule Lumen	Nucleus Cytosol Cytoskeleton Intermediate Filament Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome
	Molecular Function	RNA Binding Actin Binding Actin Monomer Binding Actin Monomer Sequestering Activity Protein Binding Enzyme Binding Protein Sequestering Activity	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Actin Filament Organization Regulation Of Cell Migration Negative Regulation Of Actin Filament Polymerization Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Inflammatory Response Negative Regulation Of Hematopoietic Stem Cell Differentiation Negative Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Proton-transporting ATP Synthase Activity, Rotational Mechanism Positive Regulation Of Endothelial Cell Chemotaxis Positive Regulation Of ATP Biosynthetic Process	Morphogenesis Of An Epithelium Cytoskeleton Organization Epithelial Cell Differentiation Regulation Of Translation In Response To Stress Intermediate Filament Organization
Pathways		Platelet degranulation	Keratinization Formation of the cornified envelope
Drugs
Diseases			White sponge nevus
GWAS		Asthma ( 30929738) Asthma (childhood onset) ( 30929738)
Interacting Genes		38 interacting genes: ACTA1 ACTA2 ACTB ACTG1 AKAP8L ALAS1 ANXA7 APLP1 CDKN1A COG6 FAM118B FHL3 GOLGA6L9 GRB7 HSF2BP IGSF21 ILK KRT13 KRT15 KRT31 KRT34 KRT36 KRT40 KRTAP8-1 LIMS1 PNMA1 PPP4C RAD21 RBPMS SCHIP1 SMN1 TAF1D TGM2 TK1 TRIM23 TRIM27 TRIP6 UHMK1	70 interacting genes: ABI2 ABI3 AIRIM AMOTL2 ANKRD36BP1 APC ATP5PO BLOC1S6 C1orf216 CATSPERT CCHCR1 CCNC CEP57 CEP57L1 CFTR DES DNAAF4 EIF4E2 EXOSC5 FANCG FARS2 FBF1 GFAP GLYCTK GOLGA8EP GRAP2 HGS HOOK3 IFT20 KLC3 KLC4 KRT1 KRT2 KRT20 KRT3 KRT5 KRT6A KRT6B KRT6C KRT7 KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT81 KRT85 LSM2 MOS MYH1 MYO15B NEFL NEIL3 PPP1R18 PSMA1 PSMB1 PSMB2 RTL8B SGF29 SPG21 TLE5 TMSB4X TRIM42 TSG101 TXLNA TXLNB ZNF688
Entrez ID		7114	3860
HPRD ID		02153	01016
Ensembl ID		ENSG00000205542	ENSG00000171401
Uniprot IDs		A2VCK8 P62328 Q0P5T0	A1A4E9 P13646
PDB IDs		3TU5 4PL7 4PL8
Enriched GO Terms of Interacting Partners?		Morphogenesis Of An Epithelium Structural Constituent Of Skin Epidermis Tissue Morphogenesis Intermediate Filament Organization Intermediate Filament Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Cytoskeleton Epithelial Cell Differentiation Structural Constituent Of Cytoskeleton Cytosol Structural Molecule Activity Focal Adhesion Supramolecular Fiber Organization Regulation Of Transepithelial Transport Stress Fiber Cytoskeleton Organization Mesenchyme Migration Dense Body Protein Kinase Binding Identical Protein Binding Developmental Process Morphogenesis Of A Polarized Epithelium Structural Constituent Of Postsynaptic Actin Cytoskeleton Platelet Aggregation Organelle Organization Anatomical Structure Morphogenesis Epidermis Development Actin Cytoskeleton Homotypic Cell-cell Adhesion Postsynaptic Actin Cytoskeleton Organization Cellular Response To Catecholamine Stimulus Lamellipodium Protein Localization To Cell-cell Junction Calyx Of Held Response To Catecholamine Actin Filament Postsynaptic Cytoskeleton Organization Protein Binding Regulation Of Synaptic Vesicle Endocytosis Positive Regulation Of Hepatic Stellate Cell Contraction Apical Junction Complex NuA4 Histone Acetyltransferase Complex Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Regulation Of Synaptic Vesicle Recycling Basal Body Patch Alpha-2B Adrenergic Receptor Binding Peptide Dopaminyltransferase Activity	Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Keratinization Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Intermediate Filament Cytoskeleton Cytosol Structural Constituent Of Cytoskeleton Intermediate Filament Polymerization Or Depolymerization Extracellular Exosome Cytoskeleton Cytoplasm Protein Binding Proteasome Core Complex Epidermis Development Actin-based Cell Projection
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