TMSB4X and TRIM23

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TMSB4X	TRIM23
Gene Name		thymosin beta 4, X-linked	tripartite motif containing 23
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Cytoskeleton Platelet Alpha Granule Lumen	Golgi Membrane Nucleus Lysosomal Membrane Extracellular Vesicular Exosome
	Molecular Function	Actin Monomer Binding Protein Binding Poly(A) RNA Binding	GTPase Activity Ubiquitin-protein Transferase Activity Protein Binding GTP Binding Enzyme Activator Activity Zinc Ion Binding Ligase Activity GDP Binding Identical Protein Binding
	Biological Process	Platelet Degranulation Actin Filament Organization Blood Coagulation Platelet Activation Sequestering Of Actin Monomers	Small GTPase Mediated Signal Transduction Viral Process Protein Ubiquitination Positive Regulation Of Catalytic Activity
Pathways		Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS
Protein-Protein Interactions		29 interactors: ACTA1 ACTA2 ACTB ACTG1 ALAS1 ANXA7 APLP1 CDKN1A FAM118B GRB7 IGSF21 ILK KRT13 KRT15 KRT31 KRT40 LIMS1 PNMA1 PPP4C RAD21 RBPMS SCHIP1 SMN1 TAF1D TGM2 TK1 TRIM23 TRIM27 TRIP6	137 interactors: AKTIP ANKRD36BP1 AQP1 ARFGAP1 ARHGEF3 ARNT2 ATPAF2 ATXN7 BAG1 C10orf10 C19orf57 C8orf33 CARD9 CCDC146 CCDC25 CDC20B CDR2 CFAP53 COX5B CREB5 CXCL14 CYTH1 CYTH2 DCX DMC1 DMRT3 DOCK2 EAF2 EXOC3-AS1 FAM103A1 FAM110A FAM133A FAM193B FAM208B FAM83A FAM90A1 FBF1 FHIT FLAD1 FLJ38668 FXR2 GATA2 GEM GGA2 GMCL1P1 GPANK1 GPKOW HAUS1 HOXB5 HSPB7 IQCE IQUB JOSD1 KAT5 KIFC3 KLHL42 KRT6A LGALS8 LINC00526 LINC01018 LMO2 LNX1 LOC729603 MDM2 MKRN3 MLH1 MORN4 MRPL4 MRPL45 MTFR2 NEK6 NFU1 NXT2 PHF1 PIAS2 PIK3R2 PITX1 PKP4 POLI POLL POM121 PPIL2 PPP1R18 PSMA1 RAD18 RIBC2 RNF126 RNF213 RNF32 RNF34 RSRC2 RTP5 SF1 SH2D4A SIAH1 SLC25A6 SMG9 SNAI1 SNAI2 SNRPB SORBS3 SPG21 STK19 SUMO1P1 TBC1D22B TMSB4X TNFAIP3 TRAF1 TRAIP TRIM27 TRIM29 TRIM31 TRIM32 TRIM42 TROAP TSG101 TSHZ3 TXNDC5 UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2H UBE2I UBE2U UBOX5 USP2 USP20 USP21 UTP23 WDR25 ZC2HC1C ZNF250 ZNF564 ZNF581
Entrez ID		7114	373
HPRD ID		02153	03449
Ensembl ID		ENSG00000205542	ENSG00000113595
Uniprot IDs		A2VCK8 P62328 Q0P5T0	P36406
PDB IDs		1UY5 3TU5
Enriched GO Terms of Interacting Partners?		Cellular Component Assembly Cell Junction Assembly Platelet Aggregation Anatomical Structure Development Response To Stimulus Cell Aging Cell-cell Junction Organization Hemostasis Protein Oligomerization Epithelium Development Adherens Junction Organization Developmental Process Tissue Development Regulation Of Body Fluid Levels Cell-matrix Adhesion Regulation Of Protein Import Into Nucleus Blood Coagulation Cellular Response To Stimulus Platelet Activation Fetal Process Involved In Parturition Regulation Of Protein Localization To Nucleus Cell Adhesion Negative Regulation Of Neural Precursor Cell Proliferation Regulation Of Nucleocytoplasmic Transport Cell-substrate Adhesion Negative Regulation Of Protein Kinase Activity Positive Regulation Of Cell-matrix Adhesion Positive Regulation Of Signal Transduction Negative Regulation Of Kinase Activity Multicellular Organismal Development Retina Homeostasis Response To Organic Cyclic Compound Single Organismal Cell-cell Adhesion Negative Regulation Of Interleukin-2 Secretion Skeletal Muscle Cell Proliferation Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Skeletal Muscle Fiber Adaptation Negative Regulation Of Gene Expression System Development Regulation Of Intracellular Protein Transport Phagocytosis Organ Development Fc Receptor Signaling Pathway Negative Regulation Of Gene Expression, Epigenetic Myofibril Assembly Cellular Response To Norepinephrine Stimulus Wound Healing Negative Regulation Of Transferase Activity Regulation Of Protein Transport Protein Complex Assembly	Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Regulation Of Protein Catabolic Process Proteolysis Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Apoptotic Process Programmed Cell Death Regulation Of Metabolic Process Cellular Response To Stress Positive Regulation Of Metabolic Process Cell Death Death Gene Expression RNA Biosynthetic Process Transcription, DNA-templated Negative Regulation Of RNA Biosynthetic Process Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Biosynthetic Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Hypoxia Protein Metabolic Process Cellular Response To Decreased Oxygen Levels Regulation Of Transcription, DNA-templated Regulation Of Proteolysis Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Oxygen Levels Regulation Of Cellular Protein Metabolic Process Nucleobase-containing Compound Metabolic Process
Tagcloud ?		aldo3 bhlhb2 bnip3 bnip31 cdknla cnn2 cobalt eno2 exerting f10 fdr hk2 itga4 lgals3 mcam mimicry mxil nominal nppb pfkp pkp2 probesets sap30 selenbpl singular u74av2 unsupervised vegfa wise	344r abrogated adaptor antiviral conjugation defense e3 ectopic embryo helicase ikkgamma innate irf3 k165 k27 lys mda5 modulator multipoints nemo polyubiquitination rig substantially tightly tlr3 tlrs toll triparite ubiquitin
Tagcloud (Difference) ?		aldo3 bhlhb2 bnip3 bnip31 cdknla cnn2 cobalt eno2 exerting f10 fdr hk2 itga4 lgals3 mcam mimicry mxil nominal nppb pfkp pkp2 probesets sap30 selenbpl singular u74av2 unsupervised vegfa wise	344r abrogated adaptor antiviral conjugation defense e3 ectopic embryo helicase ikkgamma innate irf3 k165 k27 lys mda5 modulator multipoints nemo polyubiquitination rig substantially tightly tlr3 tlrs toll triparite ubiquitin
Tagcloud (Intersection) ?