PRPF38A and CHERP

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		PRPF38A	CHERP
Gene Name		pre-mRNA processing factor 38A	calcium homeostasis endoplasmic reticulum protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Membrane Precatalytic Spliceosome	Cytoplasm Membrane Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Poly(A) RNA Binding	Protein Binding Ion Channel Binding Poly(A) RNA Binding
	Biological Process	MRNA Processing RNA Splicing	RNA Processing Cellular Calcium Ion Homeostasis Nervous System Development Negative Regulation Of Cell Proliferation Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of NFAT Protein Import Into Nucleus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: APP CHERP CLK2 CSNK2A1 DHX8 GTF3C1 JMJD6 MAPK6 POLA2 PPIG PRMT5 RBM39 RNPS1 SDCBP SDCBP2 SRPK1 SRPK2 SRSF3 SRSF4 U2AF1 ZCCHC10	28 interactors: AGGF1 APBB1 ARGLU1 CCAR1 EWSR1 FRA10AC1 GNB2L1 HNRNPH3 LUC7L PPIL4 PRPF38A PRPF40A RBM23 RBM39 RBM7 RNPS1 SART1 SF3B4 SNIP1 SNRNP27 SNRNP70 SRPK1 SRPK2 TTC14 U2AF1 U2AF2 UBC WBP4
Entrez ID		84950	10523
HPRD ID		10972	13051
Ensembl ID			ENSG00000085872
Uniprot IDs		Q8NAV1	J3QK89 Q8IWX8
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Regulation Of MRNA Splicing, Via Spliceosome MRNA 3'-end Processing Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA 3'-end Processing Cellular Nitrogen Compound Metabolic Process Termination Of RNA Polymerase II Transcription Nitrogen Compound Metabolic Process MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus Intracellular Transport Nucleocytoplasmic Transport Nuclear Transport Nuclear Export MRNA Transport RNA Transport RNA Localization Establishment Of Localization In Cell Cellular Metabolic Process Cytoplasmic Transport Transcription, DNA-templated RNA Biosynthetic Process Cellular Localization Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Positive Regulation Of Viral Genome Replication Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Protein Phosphorylation Cellular Protein Modification Process Negative Regulation Of Viral Genome Replication Nuclear Speck Organization Histone H3-R2 Demethylation Histone H4-R3 Demethylation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Regulation Of RNA Metabolic Process Regulation Of Viral Genome Replication Positive Regulation Of Viral Process	RNA Processing MRNA Processing RNA Splicing MRNA Metabolic Process RNA Metabolic Process Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing Cellular Metabolic Process Positive Regulation Of RNA Splicing Termination Of RNA Polymerase II Transcription Metabolic Process MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing MRNA Cis Splicing, Via Spliceosome Regulation Of Gene Expression Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Nitrogen Compound Metabolic Process RNA 3'-end Processing Negative Regulation Of RNA Splicing Regulation Of RNA Metabolic Process Positive Regulation Of Viral Genome Replication Nuclear Export MRNA Transport Positive Regulation Of Apoptotic Process Regulation Of Cell Cycle Positive Regulation Of Programmed Cell Death Positive Regulation Of MRNA Splicing, Via Spliceosome Cell Cycle Transcription, DNA-templated Positive Regulation Of Cell Death Cellular Process RNA Transport RNA Localization RNA Biosynthetic Process Ribonucleoprotein Complex Assembly Negative Regulation Of Viral Genome Replication Nuclear Speck Organization Maturation Of 5S RRNA Negative Regulation Of Thymidylate Synthase Biosynthetic Process
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