PRPF38A and RNPS1

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		PRPF38A	RNPS1
Gene Name		pre-mRNA processing factor 38A	RNA binding protein S1, serine-rich domain
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Membrane Precatalytic Spliceosome	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Exon-exon Junction Complex ASAP Complex
	Molecular Function	Protein Binding Poly(A) RNA Binding	Nucleotide Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Poly(A) RNA Binding
	Biological Process	MRNA Processing RNA Splicing	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing Positive Regulation Of Apoptotic Process Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways			Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: APP CHERP CLK2 CSNK2A1 DHX8 GTF3C1 JMJD6 MAPK6 POLA2 PPIG PRMT5 RBM39 RNPS1 SDCBP SDCBP2 SRPK1 SRPK2 SRSF3 SRSF4 U2AF1 ZCCHC10	34 interactors: ACIN1 CHERP CLK2 DVL2 HEXIM2 HOXD4 LUC7L3 NKTR PIN1 PNN PRPF38A RBM8A SAP18 SART3 SDCBP2 SRP54 SRPK1 SRPK2 SRSF1 SRSF11 SRSF4 SRSF6 TAF2 TRA2A TRA2B TRIM41 U2AF1 UBQLN4 UPF2 YWHAB YWHAG ZBTB14 ZNF473 ZNF490
Entrez ID		84950	10921
HPRD ID		10972	07341
Ensembl ID			ENSG00000205937
Uniprot IDs		Q8NAV1	D3DU92 Q15287
PDB IDs			4A8X
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Regulation Of MRNA Splicing, Via Spliceosome MRNA 3'-end Processing Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA 3'-end Processing Cellular Nitrogen Compound Metabolic Process Termination Of RNA Polymerase II Transcription Nitrogen Compound Metabolic Process MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus Intracellular Transport Nucleocytoplasmic Transport Nuclear Transport Nuclear Export MRNA Transport RNA Transport RNA Localization Establishment Of Localization In Cell Cellular Metabolic Process Cytoplasmic Transport Transcription, DNA-templated RNA Biosynthetic Process Cellular Localization Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Positive Regulation Of Viral Genome Replication Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Protein Phosphorylation Cellular Protein Modification Process Negative Regulation Of Viral Genome Replication Nuclear Speck Organization Histone H3-R2 Demethylation Histone H4-R3 Demethylation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Regulation Of RNA Metabolic Process Regulation Of Viral Genome Replication Positive Regulation Of Viral Process	MRNA Processing MRNA Metabolic Process RNA Splicing RNA Processing Gene Expression Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Splicing, Via Spliceosome RNA Metabolic Process Regulation Of MRNA Processing Termination Of RNA Polymerase II Transcription MRNA Export From Nucleus Nucleobase-containing Compound Metabolic Process DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA 3'-end Processing Nuclear Export MRNA Transport Nitrogen Compound Metabolic Process RNA Transport RNA Localization Cellular Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleocytoplasmic Transport Nuclear Transport Transcription, DNA-templated RNA Biosynthetic Process Cytoplasmic Transport Intracellular Transport Regulation Of Gene Expression Spliceosomal Complex Assembly Regulation Of RNA Metabolic Process Transcription From RNA Polymerase II Promoter Ribonucleoprotein Complex Assembly Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Establishment Of Localization In Cell Cellular Localization Macromolecule Biosynthetic Process Regulation Of Metabolic Process MRNA Splice Site Selection Metabolic Process Ribonucleoprotein Complex Biogenesis
Tagcloud ?			acinus bcl constructs corepressor demonstrates driven enhances explored inc isoforms manner minigene periodicals physiol promoters ra rar rarbeta repressed responsive retinoic rrm splice splicing stimulates varying weak weaker wiley
Tagcloud (Difference) ?			acinus bcl constructs corepressor demonstrates driven enhances explored inc isoforms manner minigene periodicals physiol promoters ra rar rarbeta repressed responsive retinoic rrm splice splicing stimulates varying weak weaker wiley
Tagcloud (Intersection) ?