PRPF38A and SRSF4

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid, two hybrid)

		PRPF38A	SRSF4
Description		pre-mRNA processing factor 38A	serine and arginine rich splicing factor 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome	Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	RNA Binding Protein Binding	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Sequence-specific MRNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	RNA Splicing, Via Transesterification Reactions Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Response To Insulin Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways		mRNA Splicing - Major Pathway	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination
Drugs			Artenimol
Diseases
GWAS			Carotid plaque maximum area ( 32469969) Hematocrit ( 32888494) Hemoglobin ( 32888494) Mean area of carotid plaque ( 32469969) Schizophrenia ( 26531332) Tourette syndrome ( 30818990)
Interacting Genes		29 interacting genes: AP2M1 APP CHERP CLK1 CLK2 CSNK2A1 DHX8 DVL3 GTF3C1 JMJD6 LUC7L2 MAPK6 POLA2 PPIG PRMT5 RBM39 RDX RNPS1 SDCBP SDCBP2 SRPK1 SRPK2 SRRM4 SRSF4 SRSF7 SRSF8 U2AF1 UBC ZCCHC10	28 interacting genes: CPSF7 DYRK1A ERAL1 FUS GEMIN2 HAP1 HTATSF1 NXF1 PNN PPARGC1A PRPF38A PRRC2B SART1 SCAF11 SMURF1 SMURF2 SREK1 SRPK1 SRRM2 SRRM4 SRSF10 SRSF2 SRSF6 TICAM1 TRA2B UBE2I USP7 ZDHHC17
Entrez ID		84950	6429
HPRD ID		10972	09052
Ensembl ID		ENSG00000134748	ENSG00000116350
Uniprot IDs		Q8NAV1	Q08170
PDB IDs		4RZ9 4RZA 5F5S 5O9Z 6AHD 7AAV 7ABF 7ABG 7ABI 8H6K 8Q7N 8QO9 8QPE 8QZS
Enriched GO Terms of Interacting Partners?		Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing RNA Splicing Nuclear Speck MRNA Processing Regulation Of MRNA Metabolic Process MRNA Metabolic Process RNA Binding RNA Processing RNA Metabolic Process Nucleoplasm Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleic Acid Metabolic Process Nucleic Acid Binding Nucleus Nucleobase-containing Compound Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Protein Serine Kinase Activity Frizzled Binding Macromolecule Metabolic Process RS Domain Binding Protein Serine/threonine Kinase Activity MRNA Binding Protein Kinase Activity Protein Heterodimerization Activity Regulation Of Receptor Internalization Protein-RNA Complex Assembly Regulation Of Gene Expression RNA Splicing, Via Transesterification Reactions Kinase Activity Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of JNK Cascade Negative Regulation Of MRNA Metabolic Process Low-density Lipoprotein Particle Receptor Binding Protein Binding Positive Regulation Of Receptor Internalization Protein Serine/threonine/tyrosine Kinase Activity Neuron Maturation Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Viral Genome Replication Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway	RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing RNA Binding RNA Splicing, Via Transesterification Reactions Nuclear Speck RNA Metabolic Process Nucleic Acid Metabolic Process Regulation Of RNA Splicing Spliceosomal Complex Regulation Of MRNA Splicing, Via Spliceosome Nucleoplasm MRNA Splicing, Via Spliceosome Protein-RNA Complex Assembly Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process MRNA Binding Nucleic Acid Binding Regulation Of MRNA Metabolic Process Spliceosomal Complex Assembly Nucleus Protein-containing Complex Assembly Negative Regulation Of MRNA Splicing, Via Spliceosome Protein-containing Complex Organization Negative Regulation Of RNA Splicing Negative Regulation Of MRNA Metabolic Process PML Body Cellular Component Assembly Spliceosomal SnRNP Assembly U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome Pre-mRNA Binding Presynaptic Cytosol Postsynaptic Cytosol Protein Binding Nuclear Export MRNA Splice Site Recognition Wnt Signaling Pathway, Planar Cell Polarity Pathway Histone H3T45 Kinase Activity SUMO Conjugating Enzyme Activity Positive Regulation Of Neurotrophin Production Maturation Of 5S RRNA Perforant Pathway To Dendrate Granule Cell Synapse Engulfment Of Target By Autophagosome Positive Regulation Of RNA Splicing Regulation Of Amyloid-beta Formation
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