LINC00839 and MYO7A

Number of citations of the paper that reports this interaction (PubMedID 30631154)
76

Data Source:
BioGRID (unspecified method)

		LINC00839	MYO7A
Description		long intergenic non-protein coding RNA 839	myosin VIIA
Image		No pdb structure
GO Annotations	Cellular Component		Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Lysosomal Membrane Cytosol Cytoskeleton Microvillus Cell Cortex Actin Cytoskeleton Membrane Apical Plasma Membrane Myosin Complex Myosin VII Complex Photoreceptor Connecting Cilium Stereocilium Melanosome Synapse Photoreceptor Cell Cilium Stereocilium Base Upper Tip-link Density
	Molecular Function		Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding Protein Domain Specific Binding Spectrin Binding Identical Protein Binding ADP Binding Protein-containing Complex Binding Actin Filament Binding
	Biological Process		Phagolysosome Assembly Intracellular Protein Transport Endocytosis Phagocytosis Actin Filament Organization Lysosome Organization Sensory Organ Development Sensory Perception Visual Perception Sensory Perception Of Sound Intracellular Protein Localization Cell Projection Organization Actin Filament-based Movement Eye Photoreceptor Cell Development Inner Ear Morphogenesis Mechanoreceptor Differentiation Inner Ear Auditory Receptor Cell Differentiation Neuron Development Inner Ear Development Sensory Perception Of Light Stimulus Equilibrioception Pigment Granule Localization Pigment Granule Transport Auditory Receptor Cell Stereocilium Organization Inner Ear Receptor Cell Differentiation Inner Ear Receptor Cell Stereocilium Organization Cochlea Development Sensory Organ Morphogenesis
Pathways			The canonical retinoid cycle in rods (twilight vision) Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases			Deafness, autosomal recessive Usher syndrome (US) Deafness, autosomal dominant
GWAS			Lewy body disease ( 25188341) Post bronchodilator FEV1/FVC ratio ( 26634245) Tourette syndrome ( 30818990)
Interacting Genes		82 interacting genes: ADAMTS15 AKAP13 ALDH16A1 APOL3 BFSP1 CALM1 CC2D1B CCDC93 CDC16 CEP192 CEP295NL CHPF CIZ1 CLGN CLPTM1 COPB1 DNAH10 DPEP3 EFL1 EID2 EMX1 FAAP100 FAM13B FBXL5 HAPLN4 IQCN IRX4 JAKMIP2 KLK14 KRT1 KRT6B L1CAM LRTM3 MEX3A MEX3B MEX3C MEX3D MICAL2 MYO7A NDUFA2 NOC4L NOTCH3 NVL OS9 P4HB PABPN1 PALM3 PARP6 PHACTR1 PKD1L2 PLOD3 PNPLA3 POMT2 PRSS1 PRSS3 PTBP1 PTEN PTPRA QSOX2 RAPGEF6 RIF1 RPLP2 RPTOR RYR2 SEMA4D SEPTIN12 SEPTIN9 SERHL2 SLC7A14 SOWAHB SREBF2 SYNE1 SYNE3 TAS1R3 TCF24 TMC4 TRO UBE2S VANGL1 YAP1 YIPF1 ZFPL1	12 interacting genes: ACTA1 CALM1 CDH23 KEAP1 KHDRBS1 LINC00839 MAP2 MYRIP PRKAR1A USH1C VEZT WHRN
Entrez ID		84856	4647
HPRD ID		17516	02043
Ensembl ID		ENSG00000185904	ENSG00000137474
Uniprot IDs			Q13402
PDB IDs			5MV9
Enriched GO Terms of Interacting Partners?			Stereocilia Ankle Link Complex Stereocilium Tip Inner Ear Receptor Cell Differentiation Myosin Binding Mechanoreceptor Differentiation Inner Ear Receptor Cell Stereocilium Organization Stereocilium Equilibrioception Cell Cycle Phase Transition G2/M Transition Of Mitotic Cell Cycle Cell Cycle G2/M Phase Transition Photoreceptor Inner Segment Actin Filament Auditory Receptor Cell Stereocilium Organization Inner Ear Auditory Receptor Cell Differentiation Hair Cell Differentiation Mitotic Cell Cycle Phase Transition Sensory Perception Of Mechanical Stimulus Sensory Perception Of Sound Cytosol Neuron Projection Development Photoreceptor Cell Maintenance Sensory Perception Of Light Stimulus Synapse Apical Distal Dendrite Pyruvate Carboxylase Activity Grb2-Sos Complex Sarcomere Negative Regulation Of High Voltage-gated Calcium Channel Activity Centrosome Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cilium Dendritic Filopodium Positive Regulation Of Anterograde Synaptic Vesicle Transport Distal Dendrite Positive Regulation Of Anterograde Dense Core Granule Transport Primary Dendrite Viral RNA Genome Packaging Protein Localization To Microvillus Inner Ear Morphogenesis Photoreceptor Outer Segment Cerebellar Purkinje Cell Layer Formation Paranodal Junction Maintenance Cochlear Hair Cell Ribbon Synapse Cell Cycle G1/S Phase Transition Cell Projection Proximal Neuron Projection Dendritic Branch Positive Regulation Of Insulin Secretion Stereocilia Ankle Link
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