LINC00839 and FBXL5

Number of citations of the paper that reports this interaction (PubMedID 30631154)
76

Data Source:
BioGRID (unspecified method)

		LINC00839	FBXL5
Description		long intergenic non-protein coding RNA 839	F-box and leucine rich repeat protein 5
Image		No pdb structure
GO Annotations	Cellular Component		Ubiquitin Ligase Complex Nucleus Cytoplasm Cytosol SCF Ubiquitin Ligase Complex Perinuclear Region Of Cytoplasm
	Molecular Function		Ubiquitin-protein Transferase Activity Iron Ion Binding Protein Binding Metal Ion Binding Iron-sulfur Cluster Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process		Intracellular Iron Ion Homeostasis Protein Ubiquitination Protein Catabolic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Monoatomic Cation Homeostasis Multicellular Organismal-level Iron Ion Homeostasis Inorganic Ion Homeostasis
Pathways			Association of TriC/CCT with target proteins during biosynthesis Neddylation Iron uptake and transport Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Estimated glomerular filtration rate in non-diabetics ( 31451708) Red blood cell count ( 32888494)
Interacting Genes		82 interacting genes: ADAMTS15 AKAP13 ALDH16A1 APOL3 BFSP1 CALM1 CC2D1B CCDC93 CDC16 CEP192 CEP295NL CHPF CIZ1 CLGN CLPTM1 COPB1 DNAH10 DPEP3 EFL1 EID2 EMX1 FAAP100 FAM13B FBXL5 HAPLN4 IQCN IRX4 JAKMIP2 KLK14 KRT1 KRT6B L1CAM LRTM3 MEX3A MEX3B MEX3C MEX3D MICAL2 MYO7A NDUFA2 NOC4L NOTCH3 NVL OS9 P4HB PABPN1 PALM3 PARP6 PHACTR1 PKD1L2 PLOD3 PNPLA3 POMT2 PRSS1 PRSS3 PTBP1 PTEN PTPRA QSOX2 RAPGEF6 RIF1 RPLP2 RPTOR RYR2 SEMA4D SEPTIN12 SEPTIN9 SERHL2 SLC7A14 SOWAHB SREBF2 SYNE1 SYNE3 TAS1R3 TCF24 TMC4 TRO UBE2S VANGL1 YAP1 YIPF1 ZFPL1	10 interacting genes: CITED2 CSNK2B DCTN1 EP300 LINC00839 NABP2 ORC4 PLK1 SKP1 SNCA
Entrez ID		84856	26234
HPRD ID		17516	05739
Ensembl ID		ENSG00000185904	ENSG00000118564
Uniprot IDs			Q9UKA1
PDB IDs			3U9J 3U9M 3V5X 3V5Y 3V5Z 6VCD
Enriched GO Terms of Interacting Partners?			Tau Protein Binding Protein Domain Specific Binding Protein Destabilization Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Membrane Disassembly Nuclear Membrane Disassembly PcG Protein Complex Regulation Of Microtubule Cytoskeleton Organization Molecular Function Activator Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cytosol Regulation Of Microtubule-based Process Establishment Of Spindle Localization Establishment Of Spindle Orientation Regulation Of Mitotic Spindle Organization Nuclear Membrane Organization Establishment Of Mitotic Spindle Localization Microtubule Binding Establishment Of Organelle Localization Spindle Localization Regulation Of Organelle Organization Establishment Of Mitotic Spindle Orientation Protein Localization To Chromatin Peptidyl-lysine Propionylation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity Mitotic G2/M Transition Checkpoint Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission C-rich Strand Telomeric DNA Binding Response To Estrogen Regulation Of Microtubule Polymerization Protein-containing Complex Myeloid Cell Development Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G2/M Phase Transition Nucleus Regulation Of Protein Catabolic Process Negative Regulation Of Catabolic Process Histone H2B Acetyltransferase Activity
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