MYO7A

Gene Name		myosin VIIA
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Lysosomal Membrane Cytosol Cell Cortex Apical Plasma Membrane Myosin VII Complex Photoreceptor Connecting Cilium Stereocilium Melanosome Synapse
	Molecular Function	Microfilament Motor Activity Protein Binding Calmodulin Binding ATP Binding Protein Domain Specific Binding Spectrin Binding Actin-dependent ATPase Activity Protein Homodimerization Activity ADP Binding Actin Filament Binding
	Biological Process	Phagolysosome Assembly Intracellular Protein Transport Lysosome Organization Visual Perception Sensory Perception Of Sound Actin Filament-based Movement Eye Photoreceptor Cell Development Post-embryonic Organ Morphogenesis Sensory Perception Of Light Stimulus Equilibrioception Pigment Granule Transport Auditory Receptor Cell Stereocilium Organization
Pathways		Visual phototransduction The canonical retinoid cycle in rods (twilight vision) Diseases associated with visual transduction
Drugs
Diseases
GWAS
Protein-protein Interactions		11 interactors: ACTA1 CALM1 CDH23 DFNB31 KEAP1 KHDRBS1 MAP2 MYRIP PRKAR1A USH1C VEZT
Entrez ID		4647
HPRD ID		02043
Ensembl ID		ENSG00000137474
Uniprot IDs		B9A012 Q13402
PDB IDs
Enriched GO Terms of Interacting Partners?		Retina Homeostasis Equilibrioception Sensory Perception Of Sound Sensory Perception Of Light Stimulus Sensory Perception Of Mechanical Stimulus Tissue Homeostasis Photoreceptor Cell Maintenance Multicellular Organismal Homeostasis Multicellular Organismal Development Activation Of Phospholipase C Activity Anatomical Structure Development Positive Regulation Of Phospholipase C Activity Inner Ear Receptor Cell Differentiation Mechanoreceptor Differentiation Myofibril Assembly Positive Regulation Of Phospholipase Activity Neuromuscular Process Controlling Balance Developmental Process Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Regulation Of Cellular Localization Positive Regulation Of RNA Export From Nucleus Skeletal Muscle Fiber Adaptation Parallel Actin Filament Bundle Assembly Actomyosin Structure Organization Positive Regulation Of Cellular Protein Metabolic Process Cytoskeleton Organization Embryo Development G2/M Transition Of Mitotic Cell Cycle Neuromuscular Process Positive Regulation Of Protein Metabolic Process Energy Reserve Metabolic Process Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Proteasomal Ubiquitin-independent Protein Catabolic Process Striated Muscle Cell Development Regulation Of High Voltage-gated Calcium Channel Activity Actin Cytoskeleton Organization Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Muscle Cell Development Fibroblast Growth Factor Receptor Signaling Pathway Homeostatic Process Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Actin Filament-based Process Skeletal Muscle Thin Filament Assembly Inner Ear Development Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Response To Organic Substance Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Tagcloud ?		11q13 15q21 1e aas admixture african americans ancestry caucasian causation chr15q21 cytoskeleton dermal descent exome genotyping gwas japanese keloid keloids mapping migratory myo1e myosin nedd4 peaks predisposition rs35641839 sporadically