LINC00839 and IRX4

Number of citations of the paper that reports this interaction (PubMedID 30631154)
76

Data Source:
BioGRID (unspecified method)

		LINC00839	IRX4
Description		long intergenic non-protein coding RNA 839	iroquois homeobox 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus
	Molecular Function		RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Heart Development Neuron Differentiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Cell Development Establishment Of Animal Organ Orientation
Pathways
Drugs
Diseases
GWAS			Body mass index (adult) ( 28430825) Cardiovascular disease risk factors ( 21779381) Dental caries (decayed and filled deciduous tooth surfaces) ( 31533690) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Lack of perseverance ( 30718321) Prostate cancer ( 26443449 31562322) Spatial processing ( 31596458)
Interacting Genes		82 interacting genes: ADAMTS15 AKAP13 ALDH16A1 APOL3 BFSP1 CALM1 CC2D1B CCDC93 CDC16 CEP192 CEP295NL CHPF CIZ1 CLGN CLPTM1 COPB1 DNAH10 DPEP3 EFL1 EID2 EMX1 FAAP100 FAM13B FBXL5 HAPLN4 IQCN IRX4 JAKMIP2 KLK14 KRT1 KRT6B L1CAM LRTM3 MEX3A MEX3B MEX3C MEX3D MICAL2 MYO7A NDUFA2 NOC4L NOTCH3 NVL OS9 P4HB PABPN1 PALM3 PARP6 PHACTR1 PKD1L2 PLOD3 PNPLA3 POMT2 PRSS1 PRSS3 PTBP1 PTEN PTPRA QSOX2 RAPGEF6 RIF1 RPLP2 RPTOR RYR2 SEMA4D SEPTIN12 SEPTIN9 SERHL2 SLC7A14 SOWAHB SREBF2 SYNE1 SYNE3 TAS1R3 TCF24 TMC4 TRO UBE2S VANGL1 YAP1 YIPF1 ZFPL1	3 interacting genes: LINC00839 POU6F2 RARA
Entrez ID		84856	50805
HPRD ID		17516	09369
Ensembl ID		ENSG00000185904	ENSG00000113430
Uniprot IDs			P78413
PDB IDs
Enriched GO Terms of Interacting Partners?			DNA-binding Transcription Repressor Activity Negative Regulation Of Granulocyte Differentiation Trachea Cartilage Development Sertoli Cell Fate Commitment Prostate Gland Development Retinoic Acid-responsive Element Binding Epithelial Cell Fate Commitment Ventricular Cardiac Muscle Cell Differentiation Chondroblast Differentiation Growth Plate Cartilage Development Glandular Epithelial Cell Development Positive Regulation Of T-helper 2 Cell Differentiation Alpha-actinin Binding Protein Kinase B Binding Positive Regulation Of Interleukin-5 Production Columnar/cuboidal Epithelial Cell Development MRNA Regulatory Element Binding Translation Repressor Activity Regulation Of Granulocyte Differentiation Response To Vitamin A Heterocyclic Compound Binding Positive Regulation Of Interleukin-13 Production Embryonic Camera-type Eye Development Nuclear Protein Quality Control By The Ubiquitin-proteasome System Cellular Response To Estrogen Stimulus Positive Regulation Of Interleukin-4 Production Cartilage Development Involved In Endochondral Bone Morphogenesis Positive Regulation Of Type 2 Immune Response Retinoic Acid Receptor Signaling Pathway Negative Regulation Of MiRNA Transcription Face Development DNA-binding Transcription Factor Activity Positive Regulation Of T-helper Cell Differentiation MRNA 5'-UTR Binding Protein Kinase A Binding Regulation Of Interleukin-5 Production Retinoic Acid Binding Apoptotic Cell Clearance Outflow Tract Septum Morphogenesis Cardiac Muscle Cell Differentiation Regulation Of Interleukin-4 Production Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Regulation Of Type 2 Immune Response Negative Regulation Of Cartilage Development
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