LINC00839 and SEMA4D

Number of citations of the paper that reports this interaction (PubMedID 30631154)
76

Data Source:
BioGRID (unspecified method)

		LINC00839	SEMA4D
Description		long intergenic non-protein coding RNA 839	semaphorin 4D
Image		No pdb structure
GO Annotations	Cellular Component		Semaphorin Receptor Complex Extracellular Space Nucleoplasm Centrosome Plasma Membrane Membrane Ciliary Basal Body Postsynaptic Membrane GABA-ergic Synapse
	Molecular Function		Transmembrane Signaling Receptor Activity Signaling Receptor Binding Protein Binding Semaphorin Receptor Binding Signaling Receptor Activity Neuropilin Binding Identical Protein Binding Chemorepellent Activity Receptor Ligand Activity
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Neural Crest Cell Migration Positive Regulation Of Protein Phosphorylation Immune Response Cell Adhesion Negative Regulation Of Cell Adhesion Nervous System Development Axonogenesis Axon Guidance Regulation Of Cell Shape Cell Differentiation Positive Regulation Of Cell Migration Regulation Of Cell Projection Organization Positive Regulation Of Rho Protein Signal Transduction Negative Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Ossification Involved In Bone Maturation Negative Regulation Of Osteoblast Differentiation Positive Regulation Of Collateral Sprouting Regulation Of Dendrite Morphogenesis Positive Regulation Of Axonogenesis Negative Chemotaxis Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Synapse Assembly Bone Trabecula Morphogenesis Regulation Of Biological Quality Leukocyte Aggregation Semaphorin-plexin Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Inhibitory Synapse Assembly
Pathways			Sema4D mediated inhibition of cell attachment and migration Sema4D induced cell migration and growth-cone collapse Other semaphorin interactions
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Body mass index ( 28296344) Brain morphology (MOSTest) ( 32665545) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Mean spheric corpuscular volume ( 32888494) Refractive error ( 32231278) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		82 interacting genes: ADAMTS15 AKAP13 ALDH16A1 APOL3 BFSP1 CALM1 CC2D1B CCDC93 CDC16 CEP192 CEP295NL CHPF CIZ1 CLGN CLPTM1 COPB1 DNAH10 DPEP3 EFL1 EID2 EMX1 FAAP100 FAM13B FBXL5 HAPLN4 IQCN IRX4 JAKMIP2 KLK14 KRT1 KRT6B L1CAM LRTM3 MEX3A MEX3B MEX3C MEX3D MICAL2 MYO7A NDUFA2 NOC4L NOTCH3 NVL OS9 P4HB PABPN1 PALM3 PARP6 PHACTR1 PKD1L2 PLOD3 PNPLA3 POMT2 PRSS1 PRSS3 PTBP1 PTEN PTPRA QSOX2 RAPGEF6 RIF1 RPLP2 RPTOR RYR2 SEMA4D SEPTIN12 SEPTIN9 SERHL2 SLC7A14 SOWAHB SREBF2 SYNE1 SYNE3 TAS1R3 TCF24 TMC4 TRO UBE2S VANGL1 YAP1 YIPF1 ZFPL1	6 interacting genes: CD72 CRK DSCAM LINC00839 PLXNB1 PTPRC
Entrez ID		84856	10507
HPRD ID		17516	03520
Ensembl ID		ENSG00000185904	ENSG00000187764
Uniprot IDs			E9PFD9 Q92854
PDB IDs			1OLZ 3OL2
Enriched GO Terms of Interacting Partners?			Regulation Of Cell Adhesion Protein Tyrosine Kinase Binding Signaling Receptor Binding Regulation Of Locomotion Regulation Of Neuron Projection Development Positive Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Cell Development Positive Regulation Of Axonogenesis Negative Regulation Of Cell Adhesion Plasma Membrane Raft Distribution Negative Regulation Of Immune System Process Helper T Cell Diapedesis Regulation Of Catalytic Activity Protein Phosphorylated Amino Acid Binding Regulation Of Leukocyte Mediated Cytotoxicity Response To Cholecystokinin Post-embryonic Retina Morphogenesis In Camera-type Eye Netrin Receptor Binding Synapse Assembly Negative Regulation Of Interleukin-4-mediated Signaling Pathway Positive Regulation Of Hematopoietic Stem Cell Migration Positive Regulation Of Locomotion Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of GTPase Activity Regulation Of Cell Shape Cerebellar Neuron Development Regulation Of Axonogenesis Membrane Microdomain Regulation Of Cell Projection Organization Positive Regulation Of Cell Growth DN2 Thymocyte Differentiation Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration Regulation Of Immune Response Transmembrane Signaling Receptor Activity Negative Regulation Of B Cell Receptor Signaling Pathway Cell Adhesion Regulation Of Cell Motility Negative Regulation Of Immune Response Regulation Of Cell Migration Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Regulation Of Anatomical Structure Morphogenesis Diapedesis Positive Regulation Of Growth Cell Surface Receptor Signaling Pathway Negative Regulation Of Defense Response Cellular Response To Insulin-like Growth Factor Stimulus Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Response To Endothelin Cellular Response To Endothelin Regulation Of Lymphocyte Mediated Immunity
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