LINC00839 and PRSS3

Number of citations of the paper that reports this interaction (PubMedID 30631154)
76

Data Source:
BioGRID (unspecified method)

		LINC00839	PRSS3
Description		long intergenic non-protein coding RNA 839	serine protease 3
Image		No pdb structure
GO Annotations	Cellular Component		Extracellular Region Extracellular Space Tertiary Granule Lumen
	Molecular Function		Serine-type Endopeptidase Activity Calcium Ion Binding Protein Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity Metal Ion Binding
	Biological Process		Proteolysis Digestion Antimicrobial Humoral Response Zymogen Activation Endothelial Cell Migration
Pathways			Alpha-defensins Neutrophil degranulation Antimicrobial peptides Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin Uptake of dietary cobalamins into enterocytes
Drugs			4-(1,3,2-Dioxaborolan-2-Yloxy)Butan-1-Aminium 4-Hydroxybutan-1-Aminium 4-(Hydroxymethyl)Benzamidine Benzamidine Diamino-N-[3-(1,3,2-dioxaborolan-2-yloxy)propyl]methaniminium Guanidine-3-propanol [4-(1,3,2-Dioxaborolan-2-Yloxy)Methyl]Benzamidine 1,3,2-Dioxaborolan-2-Ol
Diseases
GWAS			Bipolar disorder ( 20351715) Hand grip strength ( 29691431) Refractive error ( 32231278) Triglycerides ( 30275531)
Interacting Genes		82 interacting genes: ADAMTS15 AKAP13 ALDH16A1 APOL3 BFSP1 CALM1 CC2D1B CCDC93 CDC16 CEP192 CEP295NL CHPF CIZ1 CLGN CLPTM1 COPB1 DNAH10 DPEP3 EFL1 EID2 EMX1 FAAP100 FAM13B FBXL5 HAPLN4 IQCN IRX4 JAKMIP2 KLK14 KRT1 KRT6B L1CAM LRTM3 MEX3A MEX3B MEX3C MEX3D MICAL2 MYO7A NDUFA2 NOC4L NOTCH3 NVL OS9 P4HB PABPN1 PALM3 PARP6 PHACTR1 PKD1L2 PLOD3 PNPLA3 POMT2 PRSS1 PRSS3 PTBP1 PTEN PTPRA QSOX2 RAPGEF6 RIF1 RPLP2 RPTOR RYR2 SEMA4D SEPTIN12 SEPTIN9 SERHL2 SLC7A14 SOWAHB SREBF2 SYNE1 SYNE3 TAS1R3 TCF24 TMC4 TRO UBE2S VANGL1 YAP1 YIPF1 ZFPL1	5 interacting genes: APP LINC00839 PKNOX1 SERPINA1 TFPI
Entrez ID		84856	5646
HPRD ID		17516	06685
Ensembl ID		ENSG00000185904	ENSG00000010438
Uniprot IDs			A0A7P0MP65 P35030 Q7Z5F4
PDB IDs			1H4W 2R9P 3L33 3L3T 3P92 3P95 4DG4 4U30 4U32 5C67 5JBT 5TP0 6BX8 6GFI
Enriched GO Terms of Interacting Partners?			Serine-type Endopeptidase Inhibitor Activity Peptidase Inhibitor Activity Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Platelet Alpha Granule Lumen Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Coagulation Blood Coagulation Hemostasis Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Hemopoiesis Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Regulation Of Body Fluid Levels Endoplasmic Reticulum Lumen Antifungal Humoral Response Nuclear Envelope Lumen Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?