MYO7A and MYRIP

Number of citations of the paper that reports this interaction (PMID 12221080)
34

Data Source:
HPRD (in vitro)

		MYO7A	MYRIP
Gene Name		myosin VIIA	myosin VIIA and Rab interacting protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Lysosomal Membrane Cytosol Cell Cortex Apical Plasma Membrane Myosin VII Complex Photoreceptor Connecting Cilium Stereocilium Melanosome Synapse	Exocyst Photoreceptor Outer Segment Actin Cytoskeleton Transport Vesicle Dense Core Granule Melanosome Synapse Perinuclear Region Of Cytoplasm
	Molecular Function	Microfilament Motor Activity Protein Binding Calmodulin Binding ATP Binding Protein Domain Specific Binding Spectrin Binding Actin-dependent ATPase Activity Protein Homodimerization Activity ADP Binding Actin Filament Binding	Actin Binding Protein Binding Zinc Ion Binding Rab GTPase Binding Protein Kinase A Binding
	Biological Process	Phagolysosome Assembly Intracellular Protein Transport Lysosome Organization Visual Perception Sensory Perception Of Sound Actin Filament-based Movement Eye Photoreceptor Cell Development Post-embryonic Organ Morphogenesis Sensory Perception Of Light Stimulus Equilibrioception Pigment Granule Transport Auditory Receptor Cell Stereocilium Organization	Intracellular Protein Transport Positive Regulation Of Insulin Secretion
Pathways		Visual phototransduction The canonical retinoid cycle in rods (twilight vision) Diseases associated with visual transduction
Drugs
Diseases
GWAS			Acute lymphoblastic leukemia (childhood) ( 23007406) Information processing speed ( 21130836) Sleep duration ( 17903308)
Protein-Protein Interactions		11 interactors: ACTA1 CALM1 CDH23 DFNB31 KEAP1 KHDRBS1 MAP2 MYRIP PRKAR1A USH1C VEZT	3 interactors: C1orf216 MYO7A RAB27A
Entrez ID		4647	25924
HPRD ID		02043	14796
Ensembl ID		ENSG00000137474	ENSG00000170011
Uniprot IDs		B9A012 Q13402	Q8NFW9
PDB IDs
Enriched GO Terms of Interacting Partners?		Retina Homeostasis Equilibrioception Sensory Perception Of Sound Sensory Perception Of Light Stimulus Sensory Perception Of Mechanical Stimulus Tissue Homeostasis Photoreceptor Cell Maintenance Multicellular Organismal Homeostasis Multicellular Organismal Development Activation Of Phospholipase C Activity Anatomical Structure Development Positive Regulation Of Phospholipase C Activity Inner Ear Receptor Cell Differentiation Mechanoreceptor Differentiation Myofibril Assembly Positive Regulation Of Phospholipase Activity Neuromuscular Process Controlling Balance Developmental Process Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Regulation Of Cellular Localization Positive Regulation Of RNA Export From Nucleus Skeletal Muscle Fiber Adaptation Parallel Actin Filament Bundle Assembly Actomyosin Structure Organization Positive Regulation Of Cellular Protein Metabolic Process Cytoskeleton Organization Embryo Development G2/M Transition Of Mitotic Cell Cycle Neuromuscular Process Positive Regulation Of Protein Metabolic Process Energy Reserve Metabolic Process Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Proteasomal Ubiquitin-independent Protein Catabolic Process Striated Muscle Cell Development Regulation Of High Voltage-gated Calcium Channel Activity Actin Cytoskeleton Organization Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Muscle Cell Development Fibroblast Growth Factor Receptor Signaling Pathway Homeostatic Process Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Actin Filament-based Process Skeletal Muscle Thin Filament Assembly Inner Ear Development Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Response To Organic Substance Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity	Pigment Granule Transport Cellular Pigmentation Pigmentation Establishment Of Vesicle Localization Vesicle Localization Positive Regulation Of Constitutive Secretory Pathway Complement-dependent Cytotoxicity Multivesicular Body Organization Cytotoxic T Cell Degranulation Establishment Of Organelle Localization Multivesicular Body Sorting Pathway Exosomal Secretion Organelle Localization Natural Killer Cell Degranulation Epithelial Cell Differentiation Equilibrioception T Cell Mediated Cytotoxicity Post-embryonic Organ Morphogenesis Auditory Receptor Cell Stereocilium Organization Auditory Receptor Cell Morphogenesis Phagolysosome Assembly Auditory Receptor Cell Development Intracellular Protein Transport Natural Killer Cell Activation Involved In Immune Response Inner Ear Receptor Stereocilium Organization Positive Regulation Of Regulated Secretory Pathway Natural Killer Cell Mediated Cytotoxicity Natural Killer Cell Mediated Immunity Epithelium Development Leukocyte Mediated Cytotoxicity T Cell Mediated Immunity Endosome Organization Melanosome Transport Auditory Receptor Cell Differentiation Establishment Of Melanosome Localization Melanocyte Differentiation Leukocyte Degranulation Melanosome Localization Hair Cell Differentiation Eye Photoreceptor Cell Development Regulation Of Regulated Secretory Pathway Cellular Protein Localization Inner Ear Receptor Cell Development Protein Transport Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Neuroepithelial Cell Differentiation Phagosome Maturation Vesicle-mediated Transport Establishment Of Protein Localization Photoreceptor Cell Development
Tagcloud ?		11q13 15q21 1e aas admixture african americans ancestry caucasian causation chr15q21 cytoskeleton dermal descent exome genotyping gwas japanese keloid keloids mapping migratory myo1e myosin nedd4 peaks predisposition rs35641839 sporadically
Tagcloud (Difference) ?		11q13 15q21 1e aas admixture african americans ancestry caucasian causation chr15q21 cytoskeleton dermal descent exome genotyping gwas japanese keloid keloids mapping migratory myo1e myosin nedd4 peaks predisposition rs35641839 sporadically
Tagcloud (Intersection) ?