KIF15 and MKI67

Number of citations of the paper that reports this interaction (PMID 10878014)
7

Data Source:
HPRD (two hybrid, in vivo)

		KIF15	MKI67
Gene Name		kinesin family member 15	marker of proliferation Ki-67
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Spindle Cytosol Kinesin Complex Plus-end Kinesin Complex Microtubule Membrane	Chromosome, Centromeric Region Condensed Chromosome Nucleus Nucleolus Cytoplasm Membrane
	Molecular Function	DNA Binding Motor Activity Microtubule Motor Activity ATP Binding Microtubule Binding ATPase Activity	Protein Binding ATP Binding Protein C-terminus Binding Poly(A) RNA Binding
	Biological Process	Microtubule-based Movement Mitotic Nuclear Division Blood Coagulation Metabolic Process Cell Proliferation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II	Meiotic Nuclear Division Cell Proliferation
Pathways		MHC class II antigen presentation Kinesins Factors involved in megakaryocyte development and platelet production Adaptive Immune System
Drugs
Diseases
GWAS			Select biomarker traits ( 17903293)
Protein-Protein Interactions		5 interactors: CHD3 KIAA1377 MAP1LC3A MKI67 VIM	10 interactors: CBX3 CBX5 CDK1 HINFP KIAA0368 KIF15 NIFK PRKCB SMN1 TK1
Entrez ID		56992	4288
HPRD ID		10037	08902
Ensembl ID		ENSG00000163808	ENSG00000148773
Uniprot IDs		Q9NS87	P46013
PDB IDs			1R21 2AFF
Enriched GO Terms of Interacting Partners?		Organelle Organization Spindle Organization Cytoskeleton Organization Bergmann Glial Cell Differentiation Cell Cycle Microtubule Cytoskeleton Organization Cellular Response To Nitrogen Starvation Intermediate Filament Organization Organelle Assembly Lens Fiber Cell Development Nucleophagy Astrocyte Development Mitochondrion Degradation Muscle Filament Sliding Actin-myosin Filament Sliding Lens Fiber Cell Differentiation Organelle Disassembly Cytoplasmic Microtubule Organization Intermediate Filament Cytoskeleton Organization Astrocyte Differentiation Mitotic Spindle Organization Autophagic Vacuole Assembly Intermediate Filament-based Process Actin-mediated Cell Contraction Microtubule-based Process	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Response To Copper Ion Mitotic Nuclear Envelope Disassembly Mitotic Cell Cycle Process Histone Phosphorylation Response To Wounding Nuclear Envelope Disassembly Peptidyl-threonine Phosphorylation Mitotic Cell Cycle Nuclear Envelope Organization Pronuclear Fusion Fetal Process Involved In Parturition Blood Coagulation Cell Cycle Process Hemostasis Nucleobase-containing Compound Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Skeletal Muscle Cell Proliferation Histone H3-T6 Phosphorylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleus Organization Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Body Fluid Levels Macromolecule Biosynthetic Process Cell Cycle Wound Healing Chromatin Modification DNA Damage Checkpoint G1/S Transition Of Mitotic Cell Cycle Nitrogen Compound Metabolic Process Response To Toxic Substance Response To Cortisol Thymidine Metabolic Process Chromatin Organization Regulation Of Schwann Cell Differentiation Deoxyribonucleoside Monophosphate Biosynthetic Process Positive Regulation Of B Cell Receptor Signaling Pathway Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Protein Localization To Kinetochore Cell Cycle Checkpoint Protein Localization To Chromosome, Centromeric Region Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Import Into Nucleus, Translocation Proteasomal Protein Catabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cellular Component Assembly
Tagcloud ?		accumulates bundles crosslink cytoskeleton dimeric enable enabling fibers harbors inherent kinesin kinetochore loads localizes microtubules mt mts nonmotor onto recognize recognizes repressed rigorously slide speculated spindle subsets tpx2 unfolding	analyze associations bax bcl2 birc5 bladder carcinogenesis ccnd1 ccne1 demonstrates egfr heterozygosity indices intron loh methylation methylscreen papillary polymerase positively reveal reverse suppressor technology transduction tumorigenesis urothelial vegf wwox
Tagcloud (Difference) ?		accumulates bundles crosslink cytoskeleton dimeric enable enabling fibers harbors inherent kinesin kinetochore loads localizes microtubules mt mts nonmotor onto recognize recognizes repressed rigorously slide speculated spindle subsets tpx2 unfolding	analyze associations bax bcl2 birc5 bladder carcinogenesis ccnd1 ccne1 demonstrates egfr heterozygosity indices intron loh methylation methylscreen papillary polymerase positively reveal reverse suppressor technology transduction tumorigenesis urothelial vegf wwox
Tagcloud (Intersection) ?