| Name |
major histocompatibility complex, class II, DP beta 1 |
major histocompatibility complex, class II, DQ alpha 1 |
| Structure |
|
|
| GO Annotations |
Cellular Component |
|
|
| Molecular Function |
|
|
| Biological Process |
|
|
| Pathways |
|
|
| Diseases |
|
|
| GWAS |
- Acute graft versus host disease in bone marrow transplantation (recipient effect) ( 27595289
)
- Alanine aminotransferase levels ( 34315874
)
- Anti-rubella virus IgG levels ( 30053915
)
- Antineutrophil cytoplasmic antibody-associated vasculitis ( 28029757
)
- Aspartate aminotransferase levels ( 34315874
)
- Aspirin exacerbated respiratory disease in asthmatics ( 23180272
)
- Asthma ( 31619474
)
- Autism spectrum disorder or schizophrenia ( 28540026
)
- Chronic hepatitis B infection ( 24940741
25802187
)
- Dermatomyositis ( 27153935
)
- EGFR mutation-positive lung adenocarcinoma ( 27501781
)
- Eosinophil percentage of granulocytes ( 27863252
)
- Eosinophil percentage of white cells ( 27863252
)
- Extranodal natural killer T-cell lymphoma (nasal type) ( 27470079
)
- Gait speed in old age ( 28077804
)
- Hepatitis B ( 33736632
21750111
19349983
)
- Hepatitis B (viral clearance) ( 22737229
)
- Hepatitis B vaccine response ( 21764829
)
- Hip circumference adjusted for BMI ( 34021172
)
- IgA nephropathy ( 25305756
)
- Monocyte count ( 32888494
27863252
)
- Myositis ( 26291516
)
- Nephropathy ( 21399633
)
- Neutrophil count ( 32888494
)
- Nodular sclerosis Hodgkin lymphoma ( 29196614
)
- Persistent hepatitis B virus infection ( 33736632
27244555
)
- Plantar warts ( 28928442
)
- Primary biliary cholangitis ( 28425483
)
- Pulmonary arterial hypertension ( 30527956
)
- Response to hepatitis B vaccine ( 29534301
31243853
)
- Rosacea symptom severity ( 29771307
)
- Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848
)
- Severe aplastic anemia ( 32004448
)
- Sjögren's syndrome ( 28076899
24097066
)
- Systemic sclerosis ( 21779181
)
- Thyrotoxic hypokalemic periodic paralysis and Graves disease ( 31050781
)
- Wegener's granulomatosis ( 23740775
)
- White blood cell count ( 32888494
)
- White coat effect (clinic diastolic blood pressure minus ambulatory diastolic blood pressure) ( 31044621
)
|
|
| Novel Interactors |
1 novel interactors:
HLA-DQA1
|
6 novel interactors:
BRD2
HLA-DPB1
HLA-DQA2
KLHDC3
NXF1
TAL2
|
| Interacting Genes |
8 interacting genes:
CD74
COPB1
HLA-DPA1
LZTS2
MEOX2
ROBO2
RTN4
TRIP6
|
9 interacting genes:
APLP1
CD74
CDK7
HLA-DQB1
IKBKG
LRIF1
SH3GL2
TLE1
UNC119
|
| Entrez ID |
3115 |
3117 |
| HPRD ID |
00832
|
06765
|
| Ensembl ID |
ENSG00000223865
|
ENSG00000196735
|
| Uniprot IDs |
H0Y7G7
I4EC15
P04440
|
A0A173ADG5
A0A346FLH4
A0A649ZVH5
L8E864
P01909
Q5Y7C6
Q5Y7H0
Q8MH44
|
| PDB IDs |
3LQZ
4P4K
4P4R
4P57
4P5K
4P5M
7T2A
7T2B
7T2C
7T2D
|
1JK8
1S9V
1UVQ
2NNA
3PL6
4D8P
4GG6
4OZF
4OZG
4OZH
4OZI
5KS9
5KSA
5KSB
5KSU
5KSV
6MFF
6MFG
6U3M
6U3N
6XP6
7SG0
7SG1
7SG2
8VSP
8W83
8W84
8W85
8W86
|
| GO Terms Enriched among Interactors |
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