| Name |
major histocompatibility complex, class II, DP beta 1 |
roundabout guidance receptor 2 |
| Structure |
|
|
| GO Annotations |
Cellular Component |
|
|
| Molecular Function |
|
|
| Biological Process |
|
|
| Pathways |
|
|
| Diseases |
|
|
| GWAS |
- Acute graft versus host disease in bone marrow transplantation (recipient effect) ( 27595289
)
- Alanine aminotransferase levels ( 34315874
)
- Anti-rubella virus IgG levels ( 30053915
)
- Antineutrophil cytoplasmic antibody-associated vasculitis ( 28029757
)
- Aspartate aminotransferase levels ( 34315874
)
- Aspirin exacerbated respiratory disease in asthmatics ( 23180272
)
- Asthma ( 31619474
)
- Autism spectrum disorder or schizophrenia ( 28540026
)
- Chronic hepatitis B infection ( 24940741
25802187
)
- Dermatomyositis ( 27153935
)
- EGFR mutation-positive lung adenocarcinoma ( 27501781
)
- Eosinophil percentage of granulocytes ( 27863252
)
- Eosinophil percentage of white cells ( 27863252
)
- Extranodal natural killer T-cell lymphoma (nasal type) ( 27470079
)
- Gait speed in old age ( 28077804
)
- Hepatitis B ( 33736632
21750111
19349983
)
- Hepatitis B (viral clearance) ( 22737229
)
- Hepatitis B vaccine response ( 21764829
)
- Hip circumference adjusted for BMI ( 34021172
)
- IgA nephropathy ( 25305756
)
- Monocyte count ( 32888494
27863252
)
- Myositis ( 26291516
)
- Nephropathy ( 21399633
)
- Neutrophil count ( 32888494
)
- Nodular sclerosis Hodgkin lymphoma ( 29196614
)
- Persistent hepatitis B virus infection ( 33736632
27244555
)
- Plantar warts ( 28928442
)
- Primary biliary cholangitis ( 28425483
)
- Pulmonary arterial hypertension ( 30527956
)
- Response to hepatitis B vaccine ( 29534301
31243853
)
- Rosacea symptom severity ( 29771307
)
- Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848
)
- Severe aplastic anemia ( 32004448
)
- Sjögren's syndrome ( 28076899
24097066
)
- Systemic sclerosis ( 21779181
)
- Thyrotoxic hypokalemic periodic paralysis and Graves disease ( 31050781
)
- Wegener's granulomatosis ( 23740775
)
- White blood cell count ( 32888494
)
- White coat effect (clinic diastolic blood pressure minus ambulatory diastolic blood pressure) ( 31044621
)
|
- Bell's palsy ( 33602968
)
- Bitter taste perception (6-n-propylthiouracil) in obesity with metabolic syndrome ( 31005965
)
- Body size at age 10 ( 32376654
)
- Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) ( 19023125
)
- Brain morphology (min-P) ( 32665545
)
- Brain morphology (MOSTest) ( 32665545
)
- Chronotype ( 30696823
)
- Cortical surface area (MOSTest) ( 32665545
)
- Expressive vocabulary in infants ( 25226531
)
- Familial lung adenocarcinoma ( 29924316
)
- Gut microbiota alpha diversity (Chao1 index) ( 33208821
)
- Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821
)
- Hand grip strength ( 29691431
)
- Hip circumference ( 28552196
)
- LDL cholesterol levels in HIV infection ( 33109212
)
- Left-handedness ( 32989287
)
- Metabolite levels ( 23823483
)
- Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000
)
- Morning person ( 30696823
)
- Periodontitis (PAL4Q3) ( 24024966
)
- Post bronchodilator FEV1 ( 26634245
)
- Post bronchodilator FEV1/FVC ratio ( 26634245
)
- Response to ketamine in bipolar disorder or major depression (dissociation effects) ( 30552317
)
- Subcortical volume (min-P) ( 32665545
)
- Subcortical volume (MOSTest) ( 32665545
)
- Type 2 diabetes ( 30297969
)
|
| Novel Interactors |
1 novel interactors:
HLA-DQA1
|
None recorded
|
| Interacting Genes |
8 interacting genes:
CD74
COPB1
HLA-DPA1
LZTS2
MEOX2
ROBO2
RTN4
TRIP6
|
18 interacting genes:
BNIP3L
CENPU
CPE
GPR152
HLA-DPB1
NR1H2
NR4A1
OLFM2
PPP1R1B
RDH11
ROBO1
RPS6KA5
SLIT2
SLIT3
SSRP1
TMEM237
TRIM13
UBQLN4
|
| Entrez ID |
3115 |
6092 |
| HPRD ID |
00832
|
11895
|
| Ensembl ID |
ENSG00000223865
|
ENSG00000185008
|
| Uniprot IDs |
H0Y7G7
I4EC15
P04440
|
A0A8Q3SIU0
A0A8Q3SIW8
A0A8Q3WLE3
A0A994J7I9
F8W703
H7C4J7
H7C4U9
H7C4W9
Q9HCK4
|
| PDB IDs |
3LQZ
4P4K
4P4R
4P57
4P5K
4P5M
7T2A
7T2B
7T2C
7T2D
|
1UEM
1UJT
2EDJ
5NOI
6I9S
6IAA
|
| GO Terms Enriched among Interactors |
|
|