NCK2 and IRS1

  • Number of citations of the paper that reports this interaction (PMID 9843575)
  • 40

NCK2

IRS1

Gene Name NCK adaptor protein 2 insulin receptor substrate 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 80 interactors: ABI1 ABI2 ABI3 ARHGAP32 ATN1 AXIN1 AXL BCL11A CBLB CCDC33 CD3E CHN1 CPSF6 CPSF7 DDR1 DNM1 DOCK1 DOK1 DRAP1 DVL1 EEF1G EFHC2 EFNB1 EFNB2 EGFR EIF3H ERBB2 ERBB3 FAM53C FASLG FCRL2 FGFR1 FXR2 HNRNPK HOMEZ HOXC4 ILK IRS1 KHDRBS1 KIAA1217 LCP2 LIMS1 LNX1 LRRIQ3 LZTS2 MAGEA6 MASP1 MEOX2 NCKIPSD NPHS1 NR5A1 NTRK2 PAK1 PDGFRB PKN2 PRR20A PSMD10 PTK2 RASSF7 RBM26 REL SF3B4 SORBS2 SOS1 SPRY2 SRPK1 SRPK2 SYNPO TCF4 TNR TRIM27 TRIM41 TRIP6 VARS2 VPS37B WAS WASL WBP11 WIPF2 ZBTB7B 73 interactors: AKT1 ALK AP3S1 APP ATP2A1 ATP2A2 ATP2A3 BCL2L1 BCR CAV1 CDH1 CHUK CRK CSNK2A1 CSNK2B EGFR ERBB2 FBXO25 FBXW8 FER FES FYN GHR GRB10 GRB14 GRB2 IGF1R IKBKB IL4R INSR JAK1 JAK2 JAK3 MAPK1 MAPK8 MAPK9 MTOR NCK2 NEDD4 NPM1 NTRK1 PDPK1 PHIP PIK3R1 PIK3R2 PIK3R3 PLCG2 PRKCD PRKCG PRKCQ PRKCZ PTK2 PTPN1 PTPN11 PTPRC PTPRF PTPRU RAD51 ROCK1 RPS6KB1 RPTOR SH2B1 SHC1 SIK2 SOCS1 SOCS3 TUB TYK2 UBTF YWHAB YWHAE YWHAG YWHAZ
Entrez ID 8440 3667
HPRD ID 05378 00943
Ensembl ID ENSG00000071051 ENSG00000169047
Uniprot IDs E7ERP6 O43639 P35568
PDB IDs 1U5S 1WX6 1Z3K 2B86 2CIA 2FRW 2FRY 2JXB 4E6R 1IRS 1K3A 1QQG 2Z8C
Enriched GO Terms of Interacting Partners?
Tagcloud ?
accumulates  adapter  atr  becoming  cleavage  coordination  cytoskeletal  depleted  depletion  discrete  hela  hyperactive  increasingly  interconnectedness  interconnectivity  irradiation  monitored  mostly  nck1  parp  phenocopies  redundant  shortly  socs7  strikingly  translocation  undergo  uv 
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
Tagcloud (Difference) ?
accumulates  adapter  atr  becoming  cleavage  coordination  cytoskeletal  depleted  depletion  discrete  hela  hyperactive  increasingly  interconnectedness  interconnectivity  irradiation  monitored  mostly  nck1  parp  phenocopies  redundant  shortly  socs7  strikingly  translocation  undergo  uv 
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
Tagcloud (Intersection) ?