EEA1 and USO1

Number of citations of the paper that reports this interaction (PMID 10903204)
122

Data Source:
HPRD (in vivo)

		EEA1	USO1
Gene Name		early endosome antigen 1	USO1 vesicle transport factor
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Early Endosome Cytosol Serine-pyruvate Aminotransferase Complex Membrane Extrinsic Component Of Plasma Membrane Cytoplasmic Vesicle Early Endosome Membrane Axonal Spine Recycling Endosome Extracellular Vesicular Exosome	Golgi Membrane Nucleolus Endoplasmic Reticulum Golgi Apparatus Golgi Stack Cytosol ER To Golgi Transport Vesicle Membrane Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Calmodulin Binding 1-phosphatidylinositol Binding Zinc Ion Binding GTP-dependent Protein Binding Protein Homodimerization Activity	Protein Transporter Activity Poly(A) RNA Binding
	Biological Process	Endocytosis Vesicle Fusion Synaptic Vesicle To Endosome Fusion Early Endosome To Late Endosome Transport	Mitotic Cell Cycle Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Transcytosis Golgi Vesicle Docking Vesicle Fusion With Golgi Apparatus Membrane Fusion
Pathways		Toll-Like Receptors Cascades Toll Like Receptor 9 (TLR9) Cascade Innate Immune System	Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase
Drugs		Inositol 1,3-Bisphosphate
Diseases
GWAS
Protein-Protein Interactions		11 interactors: IGF1R MAPK14 RAB22A RAB5A RAB5B RAB5C STX12 STX6 TOM1 USO1 ZFYVE16	24 interactors: AKAP9 BET1L C1orf94 CASP3 CASP8 CSNK2B DUSP12 EEA1 GABPB1 GAK GBF1 GOLGA2 GOLGB1 GOSR1 GOSR2 NSF PHYKPL PLCG1 RAB1A SCFD1 STX5 STXBP1 XPO7 YKT6
Entrez ID		8411	8615
HPRD ID		05460	09135
Ensembl ID		ENSG00000102189	ENSG00000138768
Uniprot IDs		Q15075	O60763
PDB IDs		1HYI 1HYJ 1JOC 3MJH	2W3C
Enriched GO Terms of Interacting Partners?		Intracellular Protein Transport Endosomal Transport Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Establishment Of Localization In Cell Rab Protein Signal Transduction Vesicle-mediated Transport Ras Protein Signal Transduction Cellular Localization Endosome Organization Regulation Of Endocytosis Vesicle Fusion Vesicle Organization Plasma Membrane To Endosome Transport Small GTPase Mediated Signal Transduction Organelle Fusion Cytoplasmic Transport Regulation Of Vesicle-mediated Transport Membrane Fusion Transport Intracellular Signal Transduction Regulation Of Cellular Component Organization Organelle Organization P38MAPK Cascade Inactivation Of MAPKK Activity Vesicle Docking Membrane Docking Endomembrane System Organization Regulation Of Vesicle Size Golgi Vesicle Docking Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Endosome Size Positive Regulation Of Brown Fat Cell Differentiation Myoblast Differentiation Involved In Skeletal Muscle Regeneration Regulation Of Brown Fat Cell Differentiation Endocytosis Golgi Ribbon Formation Signal Transduction Positive Regulation Of Steroid Hormone Biosynthetic Process Exocrine Pancreas Development Vesicle Fusion With Golgi Apparatus Positive Regulation Of Hormone Biosynthetic Process 3'-UTR-mediated MRNA Stabilization Stress-induced Premature Senescence Signaling Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Protein Targeting To Lysosome	Membrane Fusion Golgi Vesicle Transport Vesicle-mediated Transport Vesicle Organization Membrane Organization Retrograde Transport, Endosome To Golgi Vesicle Docking Membrane Docking ER To Golgi Vesicle-mediated Transport Endosomal Transport Intracellular Transport Establishment Of Localization In Cell Cytoplasmic Transport Vesicle Fusion Protein Transport Establishment Of Protein Localization Cellular Localization Organelle Fusion Golgi Organization Establishment Of Vesicle Localization Post-Golgi Vesicle-mediated Transport Vesicle Localization Endomembrane System Organization Protein Localization Transport Organelle Organization Positive Regulation Of Protein Metabolic Process Establishment Of Organelle Localization Vesicle Docking Involved In Exocytosis Positive Regulation Of Metabolic Process Intra-Golgi Vesicle-mediated Transport Endocytosis Vesicle Fusion With Golgi Apparatus Organelle Localization Positive Regulation Of Cellular Metabolic Process Secretion By Cell Exocytosis Secretion Regulation Of Cellular Localization Cell Morphogenesis Regulation Of Vesicle-mediated Transport Positive Regulation Of Cellular Protein Metabolic Process Cell Morphogenesis Involved In Differentiation Retrograde Vesicle-mediated Transport, Golgi To ER Synaptic Vesicle Endocytosis Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Synaptic Vesicle Recycling Regulation Of Protein Metabolic Process Regulation Of Intracellular Transport Regulation Of Kinase Activity
Tagcloud ?		appl1 characterised colocalisation colocalises compartments employ endocytic endosome endosomes engages entered escrt gradually intermediates intralumenal labelled localise localises move snx15 solely sorts subpixel suite transit transporting ubiquitinated vacuolar whilst	absorbed altogether autophagosomes biogenesis coat compartment copi copii cups endosomal enter exit export golgi grh1 pik1 relocates relocation return sec7 secrete sed5 snare sort starvation tethering unconventional vacuole vps34
Tagcloud (Difference) ?		appl1 characterised colocalisation colocalises compartments employ endocytic endosome endosomes engages entered escrt gradually intermediates intralumenal labelled localise localises move snx15 solely sorts subpixel suite transit transporting ubiquitinated vacuolar whilst	absorbed altogether autophagosomes biogenesis coat compartment copi copii cups endosomal enter exit export golgi grh1 pik1 relocates relocation return sec7 secrete sed5 snare sort starvation tethering unconventional vacuole vps34
Tagcloud (Intersection) ?